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17 Cards in this Set
- Front
- Back
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First line of defense cells |
Myeloid cells provide non specific immunity |
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Neutrophils |
1st to arrive and kill invaders marines of phagocytic cells |
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Eosinophils |
Associated with allergies and parasites neutralize basophils and mast cells |
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Basophil |
Short life hypersensitivity reactions granules contain histamine and heparin IgE binds to cell wall |
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Mast cells |
Long life hypersensitivity reactions found in connective tissue binds IgE/anaphylatoxins |
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Monocytes |
Migrates to tissues to differentiate into macrophages |
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Macrophage |
Clear debris presents antigens to T cells (APC) phagocytosis secretion of pro-inflammatory cytokines |
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Dendritic cell |
Efficient activating and directing T cell activation and development most potent phagocytic cell in tissue phagocytize Ag and presents to T cells |
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Natural killer cells |
Kills microbe infected cells secretes cytokines to activate macrophages distinct from B and T cells |
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Antigen presenting cells (APC) |
Macrophages, B cells, dendritic cells acquired immunity depends on APC APC interact with Th cells have MHC |
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T cells function |
Immunoregulation and cell mediated immunity |
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B cells function |
Antibody production and humoral immunity only cell to produce a memory response |
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T cell receptor (TCR) |
TCR unique for epitope on mature T cells recognize Ag when presented with MHC |
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Major histocompatbility complex (MHC) |
Special molecules on APC required when presenting antigens to T cells |
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T helper (Th) |
Interacts with APC activates to become effector cell |
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T cytoxic (Tc) |
Recognizes altered self cells and cells infected with microbes/tumor cells influenced by Th cells activated Th cells differentiate into Tc cells |
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Toll like receptors |
receptors on WBC cell surfaces that recognize BROAD structures (primitive) and trigger pathways that promote inflammation |
