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13 Cards in this Set
- Front
- Back
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4 Functions of the GI tract?
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Digestion
Absorption of Nutrients Barrier Mucosal Immunity |
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What two compounds did Paul Ehlrich work with in 1891?
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Ricin and Abrin
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How much surface area in GI tract?
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200-300 m^2
One cell thick |
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In addition to their normal immunological function, what additional function does IgA have in the gut?
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They can transport pathogens from the basolateral membrane back into the lumen.
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What type of response is prefered in the gut?
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Th2 response.
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Difference between Th1 and Th2 response?
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Th1 - Pro inflammatory
Th2 - Pro Antibody |
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What are the three types of cells that reside in Peyer's Patches, and at what rates?
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B cells (IgA) 50-70%
Naive T Cells (10-30%) Unique types of dendritic cells. |
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What is the function of the M cells in the Peyer's Patches?
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Sampling Center
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What do Peyer's Patches dendritic cells secrete in the resting states?
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IL-10
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What do dendritic cells express on their surface?
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CD103
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How many dendritic cells emigrate to the Mesenteric Lymph Node each day?
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5-10%
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How many Intraepithelial Lymphocytes are in the gut
What type of cells are they primarily? |
10-15 for every 100 epithelial cells.
CD8+ T cells, 90% |
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How do intestinal epithelial cells communicate with T cells?
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MHC class-II
NO OTHER STIMULATORY MOLECULES |
