Immunology Chapter 2 - Organs Of The Immune System

Front 1

thymus and bone marrow

Back 1

primary lymphoid organs

Front 2

lymph nodes, the spleen, and various mucosa-associated lymphoid tissues (MALT) such as gut-associated lymphoid tissue (GALT)

Back 2

secondary lymphoid organs

Front 3

capable of mounting an immune response

Back 3

immunocompetent

Front 4

this outer compartment is densely packed w/ immature T cells, called thymocytes

Back 4

thymus cortex

Front 5

inner compartment sparsely populated w/ thymocytes

Back 5

thymus medulla

Front 6

congenital birth defect in which the thymus fails to develop, and there is an absence of circulating T cells and of cell-mediated immunity and an increase in infectious disease

Back 6

DiGeorge's syndrome (humans)
nude mice (mice)

Front 7

patch of tissue embedded in the wall of the intestine called the ileal ____ _____, which contains a large number of B cells as well as T cells
during gestation

Back 7

Peyer's patch

Front 8

the largest lymphatic vessel

Back 8

thoracic duct

Front 9

until activated by antigen, a lymphoid follicle is called this
comprises a network of follicular dendritic cells and small resting B cells

Back 9

primary follicle

Front 10

after antigenic challenge, a primary follicle becomes a larger ____ ____ --- a ring of concentrically packed B lymphocytes surrounding a center (GERMINAL CENTER) in which one finds a focus of proliferating B lymphocytes and an area that contains nondividing B cells and some helper T cells interspersed w/ macrophages and follicular dendritic cells

Back 10

secondary follicle

Front 11

outermost layer, contains lymphocytes (mostly B cells), macrophages, and follicular dendritic cells arranged in primary follicles

Back 11

lymph node cortex

Front 12

beneath the cortex
populated largely by T lymphocytes and also contains dendritic cells that migrated from tissues to the node

Back 12

lymph node paracortex

Front 13

more sparsely populated w/ lymphoid lineage cells, and of those present, many are plasma cells actively secreting antibody molecules

Back 13

medulla

Front 14

in spleen
consists of a network of sinusoids populated by macrophages, numerous RBCs, and few lymphocytes
site where old and defective RBCs are destroyed and removed

Back 14

red pulp

Front 15

in spleen
surrounds the branches of the splenic artery, forming a periarteriolar lymphoid sheath (PALS) populated mainly by T lymphocytes.
primary lymphoid follicles and attached to the PALS
these follicles are rich in B cells and some of them contain germinal centers

Back 15

white pulp

Front 16

peripheral to the periarteriolar lymphoid sheath (PALS)
populated by lymphocytes and macrophages
antigen is trapped by dendritic cells, which carry it the PALS

Back 16

marginal zone

Front 17

blood-borne bacterial infections

Back 17

bacteremia

Front 18

MALT
group of organized lymphoid tissues that defend vulnerable membrane surfaces of the body

Back 18

mucosa-associated lymphoid tissue

Front 19

BALT
secondary lymphoid tissue associated w/ the respiratory epithelium

Back 19

bronchus-associated lymphoid tissue

Front 20

GALT
secondary lymphoid tissue associated w/ the digestive tract

Back 20

gut-associated lymphoid tissue

Front 21

flattened epithelial cells lacked the microvilli that characterize the rest of the mucous epithelium
carries out antigen transport of small samples of foreign antigen from the lumina of the respiratory, digestive, and urogenital tracts to the underlying mucosa-associated lymphoid tissue

Back 21

M cells