Immunology Autoimmune Diseases And Tumor Markers

Front 1

Polio virus VP2 mimics what self-antigen?

Back 1

Acetylcholine

Front 2

Myelin Basic protein is mimicked by

Back 2

Measles Virus P3

Front 3

Insulin receptors are mimicked by

Back 3

Papilloma Virus VP2

Front 4

Antigen attacked in Addison's disease

Back 4

Microsomal proteins of adrenal cells

Front 5

Antigen attacked on acute disseminated encephalomyelitis

Back 5

Basic protein of myelin

Front 6

Thyroglobulin and microsomal antigens are attacked in what autoimmune disease?

Back 6

Hashimoto's Thyroiditis

Front 7

Antigen attacked on Type 1 DM

Back 7

Islet Cells

Front 8

Type 4 collagen membranes are attacked in what disease?

Back 8

Goodpastures Syndrome

Front 9

TSH receptors are attacked in what disease?

Back 9

Grave's Disease

Front 10

Acetylcholine receptors are attacked in what autoimmune disease?

Back 10

Myasthenia gravis

Front 11

Smooth muscles are attacked in what autoimmune disease?

Back 11

Autoimmune chronic active hepatitis

Front 12

Antigens attacked in Pernicious Anemia

Back 12

Gastric Parietal cell antigens, Intrinsic Factor

Front 13

Antigens attacked in Sjogren's Syndrome

Back 13

Salivary Gland nucleolar antigen

Front 14

Antigens attacked in Billiary Cirrhosis

Back 14

Mitochondria

Front 15

Striated Cardiac muscle antigens are attacked in what autoimmune disease?

Back 15

Autoimmune myocarditis

Front 16

Epidermal antigen are attacked in what disease?

Back 16

Pemphigus vulgaris

Front 17

Bullous Pemphigoid

Back 17

Attacks Epidermal Antigen

Front 18

Autoimmune rheumatic fever

Back 18

attacks heart and joint tissue organ

Front 19

In Antibiotic testing how long is the diameter of the plate and how deep is it?

Back 19

4mm depth and 6mm diameter

Front 20

Rosette uterus

Back 20

Diphylobothrium latum

Front 21

Rosette Microconidia

Back 21

Sporothrix schenkii

Front 22

Disease of Connective Tissue

Back 22

SLE

Front 23

most common manifestation of SLE

Back 23

arthritis

Front 24

Skin lesions found in SLE

Back 24

Butterfly rash or RED WOLF

Front 25

What antibody is present in SLE?

Back 25

Anti-Nuclear Antibodies

Front 26

True or False: ANA is a specific antibody for SLE

Back 26

False

Front 27

Specific antibodies detected in SLE

Back 27

Anti-smith antibody and anti-double stranded DNA

Front 28

Specific antibodies usually found in all SLE

Back 28

Anti-dsDNA

Front 29

Cell associated with SLE

Back 29

Le cell

Front 30

Le cell appearance

Back 30

PMN leukocyte with ingested LE body, often in rosette formation

Front 31

Serologic Tests for SLE

Back 31

Antinuclear Antibody Visible Method and Indirect Fluorescent Antibody Detection of ANA

Front 32

Most commonly used and well known serologic test for SLE

Back 32

Indirect Fluorescent Antibody detection of ANA

Front 33

Nucleolar fluorescent pattern is associated with what disease?

Back 33

Scleroderma

Front 34

Pattern of fluorescence for SLE

Back 34

Homogenous, Peripheral, or Speckled

Front 35

Discrete patterned fluorescence are seen in what diseases?

Back 35

Calcinosis

Reynauds

Esophageal dysmotility

Sclerodactyl

Telangietasia

Front 36

Speckle patterned fluorescence are associated with what diseases?

Back 36

SLE, RA, MCTD

Front 37

Peripheral patterned fluorescence are associated with what diseases?

Back 37

Active stage of SLE

Sjorgen's Syndrome

Front 38

Homogenous patterned fluorescence are associated with what diseases?

Back 38

Rheumatoid arthritis

SLE

Sjorgens Syndrome

MTCD

Front 39

Autoimmune disease causing chronic inflammation of the joints and periarticular tissue

Back 39

Rheumatoid Arthritis

Front 40

What is the nonspecific marker for rheumatoid arthritis?

Back 40

Rheumatoid Factor

Front 41

What is the specific marker for RA?

Back 41

anti-cyclic citrullinated peptide

Front 42

Sensitized Alligator Erythrocyte Test for RA was discovered by

Back 42

Cohen et al

Front 43

Rose-Waaler test for RA

Back 43

Sheep Cell Agglutination Test

Front 44

Latex Fixation Test for RA was discovered by

Back 44

Singer and Plotz

Front 45

Bentonite Flocculation Test was discovered by

Back 45

Bloch and Bunim

Front 46

Carcinoembryonic antigen

Back 46

GI cancer

Front 47

AFP

Back 47

hepatocellular cancer

Front 48

PSA

Back 48

prostate cancer

Front 49

Best and only specific tumor marker

Back 49

PSA

Front 50

Breast Cancer

Back 50

CA15-3

Front 51

pancreas, stomach, bile duct cancers

Back 51

CA 19-9

Front 52

Ovarian CA

Back 52

CA 125

Front 53

Gastric Cancer

Back 53

Ca 72-4

Front 54

Defined as the initial force of attraction between Fab and single epitope

Back 54

Affinity

Front 55

Definition of Avidity

Back 55

sum of all attractive forces between an antigen and an antibody

Front 56

Process wherein Thymocytes are presented with MHC molecules to make them single positive t cells

Back 56

Positive selection

Front 57

Process wherein T cells are selected through their lack of stimulation from self antigens in the medulla of the thymus

Back 57

Negative selection

Front 58

2 mechanisms of immune tolerance

Back 58

Clonal anergy and clonal deletion

Front 59

IgM attacking IgG disease

Back 59

Rheumatoid arthritis