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59 Cards in this Set
- Front
- Back
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[...] are a type of immunosuppressant that inhibits NF-kB, thereby decreasing the transcription of many cytokines. |
"Glucocorticoids are a type of immunosuppressant that inhibits NF-kB, thereby decreasing the transcription of many cytokines.
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[...] is an immunosuppressant that is converted into 6-MP and inhibits PRPP Amidotransferase.
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"Azathioprine is an immunosuppressant that is converted into 6-MP and inhibits PRPP Amidotransferase.
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[...] are a type of immunosuppressant that is associated with central obesity and hyperglycemia.
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"Glucocorticoids are a type of immunosuppressant that is associated with central obesity and hyperglycemia.
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[...] are a type of immunosuppressant that are associated with osteoporosis and muscle breakdown.
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Glucocorticoids are a type of immunosuppressant that are associated with osteoporosis and muscle breakdown.
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[...] are a type of immunosuppressant that are associated with acne and cataracts.
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Glucocorticoids are a type of immunosuppressant that are associated with acne and cataracts.
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[...] are a type of immunosuppressant that are associated with peptic ulcers.
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Glucocorticoids are a type of immunosuppressant that are associated with peptic ulcers.
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[...] are a type of immunosuppressant that are known to cause iatrogenic Cushing Syndrome.
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Glucocorticoids are a type of immunosuppressant that are known to cause iatrogenic Cushing Syndrome.
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[...] is a recombinant cytokine that functions as Erythropoietin and is used to treat anaemia, especially in renal failure.
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Epoetin alfa is a recombinant cytokine that functions as Erythropoietin and is used to treat anaemia, especially in renal failure.
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[...] and Oprelvekin are recombinant cytokines that are used to treat thrombocytopenia.
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Thrombopoietin and Oprelvekin are recombinant cytokines that are used to treat thrombocytopenia.
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Thrombopoietin and [...] are recombinant cytokines that are used to treat thrombocytopenia.
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Thrombopoietin and Oprelvekin are recombinant cytokines that are used to treat thrombocytopenia.
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[...] is a recombinant cytokine that functions as IL-11 and hence is used to treat Thrombocytopenia.
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Oprelvekin is a recombinant cytokine that functions as IL-11 and hence is used to treat Thrombocytopenia.
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[...] is a recombinant cytokine that functions as a granulocyte colony-stimulating factor (G-CSF) to induce bone marrow recovery.
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Filgrastim is a recombinant cytokine that functions as a granulocyte colony-stimulating factor (G-CSF) to induce bone marrow recovery.
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[...] is a recombinant cytokine that functions as a granulocyte-macrophage colony-stimulating factor (GM-CSF) and is used to induce bone marrow recovery.
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Sargramostim is a recombinant cytokine that functions as a granulocyte-macrophage colony-stimulating factor (GM-CSF) and is used to induce bone marrow recovery.
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[...] is a recombinant cytokine that function as IL-2 and is used in renal cell carcinoma and metastatic melanoma.
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Aldesleukin is a recombinant cytokine that function as IL-2 and is used in renal cell carcinoma and metastatic melanoma.
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Which interferon is used to treat chronic HBV and HCV?
[...] |
Which interferon is used to treat chronic HBV and HCV?
IFN-alpha |
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Which interferon is used to treat Kaposi Sarcoma?
[...] |
Which interferon is used to treat Kaposi Sarcoma?
IFN-alpha |
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Which interferon is used to treat Hairy Cell Leukemia?
[...] |
Which interferon is used to treat Hairy Cell Leukemia?
IFN-alpha |
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Which interferon is used to treat Condyloma Acuminatum?
[...] |
Which interferon is used to treat Condyloma Acuminatum?
IFN-alpha |
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Which interferon is used to treat Renal Cell Carcinoma?
[...] |
Which interferon is used to treat Renal Cell Carcinoma?
IFN-alpha |
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Which interferon is used to treat Malignant Melanoma?
[...] |
Which interferon is used to treat Malignant Melanoma?
IFN-alpha |
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Which interferon is used to treat Multiple Sclerosis?
[...] |
Which interferon is used to treat Multiple Sclerosis?
IFN-beta |
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Which interferon is used to treat Chronic Granulomatous Disease?
[...] |
Which interferon is used to treat Chronic Granulomatous Disease?
IFN-gamma |
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What is the target of the monoclonal antibody Alemtuzumab?
[...] |
What is the target of the monoclonal antibody Alemtuzumab?
CD52 in Chronic Lymphocytic Leukemia |
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What is the target of the monoclonal antibody Bevacizumab?
[...] |
What is the target of the monoclonal antibody Bevacizumab?
VEGF in colorectal cancer, renal cell carcinoma |
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What is the target of the monoclonal antibody Cetuximab?
[...] |
What is the target of the monoclonal antibody Cetuximab?
Epidermal growth factor receptor (EGFR) in stage IV colorectal cancer, head and neck cancer |
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What is the target of the monoclonal antibody Rituximab?
[...] |
What is the target of the monoclonal antibody Rituximab?
CD20 in B-cell non-Hodgkin lymphoma, Rheumaoid Arthritis and Idiopathic Thrombocytopenic Purpura |
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What is the target of the monoclonal antibody Trastuzumab?
[...] |
"What is the target of the monoclonal antibody Trastuzumab?
HER2/neu in breast cancer and some gastric cancer ""Tras-2-zumab targets HER2""" |
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What is the target of the monoclonal antibody Infliximab?
[...] |
What is the target of the monoclonal antibody Infliximab?
TNF-alpha in IBD, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriasis |
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What is the target of the monoclonal antibody Adalimumab?
[...] |
What is the target of the monoclonal antibody Adalimumab?
TNF-alpha in IBD, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriasis |
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What is the target of the monoclonal antibody Natalizumab?
[...] |
What is the target of the monoclonal antibody Natalizumab?
alpha4-integrin in MS and Crohn Disease Alpha4-integrin is an integrin protein involved with leukocyte adhesion. |
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[...] is a possible neurological complication of Natalizumab use in patients with JC virus infection.
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Progressive Multifocal Leukoencephalopathy (PML) is a possible neurological complication of Natalizumab use in patients with JC virus infection.
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What is the target of the monoclonal antibody Abciximab?
[...] |
What is the target of the monoclonal antibody Abciximab?
GpIIb/IIIa in patients that need anti-platelet action i.e. for the prevention of ischemic complications in patients undergoing percutaneous coronary intervention |
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What is the target of the monoclonal antibody Denosumab?
[...] |
What is the target of the monoclonal antibody Denosumab?
RANKL in osteoporosis; Blocking of RANKL inhibits osteoclast maturation |
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What is the target of the monoclonal antibody Digoxin Immune Fab?
[...] |
What is the target of the monoclonal antibody Digoxin Immune Fab?
Digoxin; acts as an antidote for Digoxin toxicity |
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What is the target of the monoclonal antibody Omalizumab?
[...] |
What is the target of the monoclonal antibody Omalizumab?
IgE; used to prevent allergic asthma and prevents IgE binding to FcERI |
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What is the target of the monoclonal antibody Pavilizumab?
[...] |
What is the target of the monoclonal antibody Pavilizumab?
RSV F protein Remember, F proteins on RSV allow is to make syncytia. Hence, Respiratory Syncytial Virus (RSV). |
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What is the clinical use of the monoclonal antibody Alemtuzumab?
[...] |
What is the clinical use of the monoclonal antibody Alemtuzumab?
Chronic Lymphocytic Leukemia (CLL) via CD52 |
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What is the clinical use of the monoclonal antibody Bevacizumab?
[...] |
What is the clinical use of the monoclonal antibody Bevacizumab?
Colorectal cancer; Renal cell carcinoma; via VEGF |
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What is the clinical use of the monoclonal antibody Cetuximab?
[...] |
What is the clinical use of the monoclonal antibody Cetuximab?
Stage IV colorectal cancer; Head and neck cancer; via EGFR |
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What is the clinical use of the monoclonal antibody Rituximab?
[...] |
What is the clinical use of the monoclonal antibody Rituximab?
B-cell non-Hodgkin lymphoma; Rheumatoid Arthritis; Idiopathic Thrombocytopenia Purpura; via CD20 |
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What is the clinical use of the monoclonal antibody Trastuzumab?
[...] |
What is the clinical use of the monoclonal antibody Trastuzumab?
Breast cancer; Gastric cancer; via HER2/neu |
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What is the clinical use of the monoclonal antibody Infliximab?
[...] |
What is the clinical use of the monoclonal antibody Infliximab?
IBD; Rheumatoid Arthritis; Ankylosing Spondylitis; Psoriasis; via TNF-alpha |
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What is the clinical use of the monoclonal antibody Adalimumab?
[...] |
What is the clinical use of the monoclonal antibody Adalimumab?
IBD; Rheumatoid Arthritis; Ankylosing Spondylitis; Psoriasis; via TNF-alpha |
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What is the clinical use of the monoclonal antibody Natalizumab?
[...] |
What is the clinical use of the monoclonal antibody Natalizumab?
Multiple Sclerosis; Crohn Disease; via alpha4-integrin Remember, alpha4-integrin is involved with leukocyte adhesion. |
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What is the clinical use of the monoclonal antibody Abciximab?
[...] |
What is the clinical use of the monoclonal antibody Abciximab?
Prevention of ischemic complications in patients undergoing percutaneous coronary intervention i.e. it's an antiplatelet, brah! |
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What is the clinical use of the monoclonal antibody Denosumab?
[...] |
What is the clinical use of the monoclonal antibody Denosumab?
Osteoporosis; inhibits osteoclast maturation via RANKL |
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What is the clinical use of the monoclonal antibody Digoxin Immune Fab?
[...] |
What is the clinical use of the monoclonal antibody Digoxin Immune Fab?
Antidote for Digitoxin toxicity |
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What is the clinical use of the monoclonal antibody Omalizumab?
[...] |
What is the clinical use of the monoclonal antibody Omalizumab?
Allergic asthma; prevents IgE binding to FcERI |
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What is the clinical use of the monoclonal antibody Palivizumab?
[...] |
What is the clinical use of the monoclonal antibody Palivizumab?
Prophylaxis in RSV high-risk infants; via RSV F protein |
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Which monoclonal antibody can be used to treat Chronic Lymphocytic Leukemia (CLL)?
[...] |
Which monoclonal antibody can be used to treat Chronic Lymphocytic Leukemia (CLL)?
Alemtuzumab (via CD52) |
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Which monoclonal antibody can be used to treat Idiopathic Thrombocytopenic Purpura (ITP)?
[...] |
Which monoclonal antibody can be used to treat Idiopathic Thrombocytopenic Purpura (ITP)?
Rituximab |
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Which monoclonal antibody can be used to treat Breast Cancer?
[...] |
Which monoclonal antibody can be used to treat Breast Cancer?
Trastuzumab (via HER2/neu) |
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Which monoclonal antibody can be used to treat Multiple Sclerosis?
[...] |
Which monoclonal antibody can be used to treat Multiple Sclerosis?
Natalizumab |
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Which monoclonal antibody can be used to treat Crohn Disease?
[...] |
Which monoclonal antibody can be used to treat Crohn Disease?
Natalizumab |
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Which monoclonal antibody can be used to treat Ankylosing Spondylitis?
[...] |
Which monoclonal antibody can be used to treat Ankylosing Spondylitis?
Infliximab; Adalimumab; both via TNF-alpha |
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Which monoclonal antibody can be used to treat Osteoporosis?
[...] |
Which monoclonal antibody can be used to treat Osteoporosis?
Denosumab (via RANKL) |
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Which monoclonal antibody can be used to treat Digoxin toxicity?
[...] |
Which monoclonal antibody can be used to treat Digoxin toxicity?
Digoxin Immune Fab |
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Which monoclonal antibody can be used to treat Allergic Asthma?
[...] |
Which monoclonal antibody can be used to treat Allergic Asthma?
Omalizumab |
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Which monoclonal antibody can be used as an RSV-prophylaxis for high-risk infants?
[...] |
Which monoclonal antibody can be used as an RSV-prophylaxis for high-risk infants?
Palivizumab
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