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15 Cards in this Set
- Front
- Back
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Signal required for naive t cells |
TCR and co receptor binding+co stimulatory+IL-2 |
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Effector t cell signal |
TCR and co receptor binding |
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L selection function |
Prevents return to L node |
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Function of LFA 1 & CD2 |
better binding to targets |
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Function of VLA 4 |
recruits cell to infection |
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Function of CD45RO |
TCR sensitivity |
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Binds MHC 2 on B cell |
Th2 and tfh |
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Binds MHC1 on virus infected cell |
T cell |
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Bind MHC 2 on macrophages |
Th1 |
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Binds MHC2 on APC also bound to CD4 t cell |
T reg |
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CTL killing methods |
Lyric granules and CTL polarization |
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CTL polarization |
CTL lytic granules align towards cell |
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Cell death by CTLs |
Chromatin is cleaved by nucleases, nucleus condenses and membrane is intact until late stages |
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1st CTL apoptosis pathway |
Initiated by granules, apoptosis cascade, professes make pores and deliver pores to cytoplasm |
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2nd CTL apoptosis pathway |
Initiated by binding of FAS |
