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7 Cards in this Set
- Front
- Back
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What are the different names for macrophages found in the body? |
Blood: monocytes Liver: Kpuffer cells Skins: Langerhans CNS: microglial Lung: Alveolar macrophages |
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What is the function of complement cascade? |
Activation of inflammatory pathways, recruitment of phagocytosis, opsonisation, removal of immune complexes, lysis of certain pathogens |
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What is the membrane attack complex? |
Formed from complement proteins C5b to C9 and can directly punch a hole in membrane of pathogens |
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What is an immune complex? |
Antigen, antibody and complement |
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What is the result of a complement deficency? |
Increased susceptibility to neisserial infection |
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What is the result of factor H and I deficiency? |
Haemolytic uraemic syndrome |
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What is the result of C1 esterase inhibitor deficiency? |
Hereditary angioedema |
