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16 Cards in this Set
- Front
- Back
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CD19
CD21 |
B cell co-stimulators
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CD21
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binds C3b (when CR2 binds C3b, brings CD21 to B cell)
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CD3
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marker of T cells (entire T cell count)
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CD45
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marker for leukocytes
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BCR binds
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soluble free antigens
has Ig-alpha and Ig-Beta subunits |
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TCR binds
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protein peptide fragments
CD3 and zeta subunits for signaling |
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CD1d
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Natural Killer T cells (NKT cells)
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IL-4
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IgE class switching
inhibits macrophage activity (w/ IL-10) |
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IFN-gamma
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IgG class switching
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TGF-beta
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IgA class switching
inhibits T cells |
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IL-2
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T cell growth factor and proliferation
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VLA-4 (on T cell)
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binds VCAM-1(on APC)
adhesion molecules |
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LFA-1 (on T cell)
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binds ICAM-1 (on infected cell)
adhesion molecules |
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CTLA-4
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binds B7
inhibits stimulatory signal |
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CD28 (on T cell)
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binds B7 (on APC)
increases sensitivity and lowers threshold needed for effective response |
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CD40 (on B cell)
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binds CD40 L (on T cell)
this interaction is thought to determine if B cell becomes memory or plasma cell |
