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27 Cards in this Set

  • Front
  • Back
CD1
Glycolipids, not MHC-encoded
CR4
Also alphaX, beta2, CD11c/Cd18
On DC, macrophage, neutrophils
Artemis
NHEJ factor, hairpin coding end defect
Src family
SH2, SH3
STAT
N-term, coiled coil, DNA binding domain, SH2, TAD (transcriptional activation domain)
IL-10
Jak1, Tyk2, Stat3
IL-2
Jak1, Jak3, Stat5
IFN-gamma
Jak1, Jak2, Stat1
IL-3
Jak2, Stat5
Qa-1, HLA-E
Self-Class I signal peptides
Major ligand for CD94/NKG2A
LFA-1
Also alphaL, beta2, CDlla/CD18
On T cells, macrophages, neutrophils, DC
Syk KO
Embryonic lethal
Tec family
PH, TH, SH2, SH3
IL-12
Jak2, Tyk2, Stat4
IL-6
Jak1, Stat3
IL-4
Jak1, Jak3, Stat6
IL-13
Jak2, Tyk2
M3
Mouse, N-formylated peptides
HFE
Transferrin receptor
Mac-1
Also alphaM, beta2, CD11a/CD18
On neutrophils, monocytes, macrophage
Tonegawa
1976, somatic rearrangement
B-1 B cells
CD5 on surface, make IgM natural antibodies, from fetal liver, small repertoire as they use the V closest to D, don't need T cell help, no somatic hypermutuation, no TdT
JAK
FERM, SH2, pseudokinase, kinase
Type 1 IFNs
Tyk2, Jak1, Stat1, Stat2
IL-15
Jak1, Jak3, Stat5
IL-5
Jak2, Stat5
IL-7
Jak1, Jak3, Stat5