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8 Cards in this Set

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What is an antigen

A specific foreign protein found on the surface of a cell that stimulates an immune response

What is a pathogen?

A disease causing microorganism

What are the bodies 3 defences against pathogens?

Barriers (physical/chemical)


Phagocytes


Specific Response

Physical Barriers

Upper epidermis of dead skin cells prevents entry of pathogens



Ciliated epithelia waft trapped pathogens towards stomach to be destroyed



Mucus secreted by goblet cells traps pathogens which can be expelled

3 points

Chemical barriers

Stomach acid denatures pathogens



Lysozymes in eyes hydrolyse pathogens



Sebum secreted by sebaceous glands in skin have antiseptic properties

3 points

How do bacteria cause disease?

Producing toxins

How do viruses cause disease?

By taking over the hosts cells replicating inside them and causing cell death by bursting

Describe the specific response

Phagocyte performs phagocytosis and presents pathogenic antigens on surface


T cells bind to antigens and become stimulated


T cells divide mitotically to form 3 types of T cells helper killer and memory


T helper cells stimulate B cells


T killer cells destroy body cells infected by viruses


T memory cells provide long term immunity


B cells engulf and present antigens on their surface


T helper cells bind to this


B cells are stimulated to divide by mitosis making plasma cells and memory cells


Plasma cells make antibodies


Memory cells provide long term immunity