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30 Cards in this Set
- Front
- Back
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fixes complement on C1 & C3
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IgM
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monomer on B cell surface
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IgM
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pentamer in blood stream
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IgM
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5 Fab
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IgM
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5 Fc
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IgM (when its in blood, not when its bound to mature B cell)
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2 j chains
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IgM (when its a pentamer)
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too much IgM
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Waldenstroms Macroglobulinemia
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cold agglutin
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IgM
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can we make IgM to Rh antigens?
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no
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can we make IgM to ABO antigens?
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yes
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Has only 1 function
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IgD
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function of IgD:
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marker for mature B cell (with IgM, CD 19, CD 20)
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monomer always
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IgG, IgE
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allergies
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IgE
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parasites
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IgE
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does NOT bind complement?
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IgE, IgG4, IgD
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is nonfxnal in blood, but fxnal in secretions
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IgA
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IgA's nonfxnal form
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monomer (1 Fab, 1 Fc)
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IgA's fxnal form
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dimer (2 Fab, 2Fc, 1 j-chain)
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where does IgA get its Fab portion from?
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plasma cell
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Where does IgA get its Fc portion from?
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mucosal cells
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which IL controls IgA
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IL-5
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presentation of pt with Selective IgA deficiency
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bad rxn to transfusion
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binds to complement on C1
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IgA
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uses alternative pathway for complement
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IgA
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binds to complement on C2
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IgG
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most antigen in body
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IgG
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crosses placenta
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IgG1
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# 1 opsonin
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IgG2
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has memory response
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IgG
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