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4 Cards in this Set
- Front
- Back
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Name apcs |
Sensitization phase: Dendritic cells Langerhans cells Elicitation phase: Monocytes Macrophages |
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Treg cells |
CD4+CD25+ Regulate immune response. Lack of them develops secere immune dysregulation |
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Proprietes d'un allergene |
Biochemical properties Stimulating factors of innate immunity Stability of allergen in tissues Dose and time of stay in lymphatic organs |
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Th1 vs Th2 |
Th2 secrete IL4, IL5, IL13 Favors IgE synthesis and eosinophilia Important effector molecules Infiltration in affected tissues Th1: a fraction of immune response in allergies Typically involved eradication of intracellular organisms Contributes to chronicity and effector phase IFNg, TNFa and FAS ligand--pathogenic event formation of lesions |
