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52 Cards in this Set
- Front
- Back
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Is donor occupation required information? |
No. |
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What are some possible causes for permanent deferral? |
History of hepatitis after age 11, positive hepatitis C test result, positive HTLV-1 antibody, positive anti-HBc test result |
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Immunization for rubella would result in a temporary deferral for how long? |
4 weeks |
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Which of the following tests is not required as part of the donor processing procedure for allogenic donations: ABO, Rh, STS, Anti-HTLV 1, or Anti-CMV? |
Anti-CMV |
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Each unit of cryoprecipitate prepared from whole blood should contain approximately how many units of AHF activity? |
80 IU |
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Platelet concentrates prepared by apheresis should contain how many platelets? |
3 x 10^11 |
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What is the required store temperature for frozen RBCs using a high glycerol method? |
-65 degrees Celsius |
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Once thawed, FFP must be transfused within _____ hours. |
24 hours. |
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QC for RBCs requires a maximum hematocrit level of ____%. |
80% |
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What are AHF concentrates used to treat?
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Hemophilia A
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Prothrombin complex concentrates are used to treat a deficiency in what? |
Factor IX |
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RBCs that have been leukoreduced must contain less than ________ WBCs and retain at least _______% of original RBCs.
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5 x 10^6; 85%
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Random-donor platelets that have been leukoreduced must contain less than _________ leukocytes. |
8.3 x 10^5 |
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A single unit of FFP or PF24 should contain _____mL of plasma.
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150-250 mL
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Cryoprecipitate that has been pooled must be transfused within _______ hours. |
4 hours. |
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An allogeneic blood donor should weigh at least ______ lbs. |
110 lbs (50 kg) |
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The pulse rate of a potential donor should be between ______ and ______ beats per minute. |
50 and 100 |
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The hemoglobin level of an allogeneic donor should be at least ______ g/dL. |
12.5g/dL |
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The hematocrit level of an allogeneic donor should be at least ______%. |
38% |
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The deferral period for individuals who have been treated for malaria is _____ years following therapy. |
3 years |
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Individuals who have had a blood transfusion are deferred for ______ months. |
12 months |
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A platelet pheresis donor should not take aspirin for _____ days before donation. |
3 days |
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A person with hemophilia A or B, von Willebrand disease, or severe thrombocytopenia must be permanently deferred. |
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Attenuated live viral vaccines such as German measles and chickenpox carry a ______ week deferral. |
4 week |
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Attenuated live viral vaccines (such as smallpox, measles, mumps, yellow fever and influenza) carry a ______ week deferral. |
2 week |
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A blood donor who has a positive serologic test for syphilis must be deferred for ______ months. |
12 months |
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Donors who have tested positive for the HIV antibody are deferred indefinitely. |
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Predeposit autologous donation refers to: |
blood for the donor-patient that is drawn before an anticipated transfusion and stored until use. |
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An autologous donor must have a hemoglobin of at least _____g/dL and a hematocrit level of at least _______%. |
11 g/dL; 33% |
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Intraoperative autologous transfusion refers to: |
blood collected during surgery and reinfused immediately |
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Acute normovolemic hemodilution takes place in the operating room when 1 to 3 units of whole blood are collected and the patient's volume is replaced with colloid or crystalloid. The blood is reinfused during the surgical procedure. |
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Postoperative salvage refers to: |
an autologous donation in which a drainage tube is placed in the surgical site and postoperative bleeding is salvaged, cleaned and reinfused. |
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Donor units must be tested for which biological markers? |
STS, anti-HIV-1/2, HIV-antigen, anti-HTLV I/II, HBsAg, anti-HBc and anti-HCV |
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RBCs must be prepared by a method that separates the RBCs from the plasma and results in a hematocrit level of less than or equal to ____%. |
80%. |
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Irradiated RBCs must be given a radiation dose of at least ____ Gy to the middle of the bag/canister, after which the expiration date of the product changes to _____days from the time or irradiation or the original outdate (whichever comes first).
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25 Gy; 28 days
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Leukocyte-reduced RBCs are products in which the absolute leukocyte count is less than _________. |
5 x 10^6 |
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Random-donor platelets must contain at least _____________ platelets while single-donor platelets must contain at least ______________ platelets. Each carries a shelf life of ______ days. |
5.5 x 10^10; 3 x 10^11; 5 days |
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FFP must be prepared within _____ hours of collection of CPD, CPDA-1 and CP2D. It is stored at ____________ degrees Celsius for _________ months. |
8 hours; -18 degrees; 12 months |
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Cryoprecipitate is prepared from _______ and contains at least _____ units of antihemophilic factor and ____________ mg of fibrinogen. This product is indicated for hemophilia A, factor XIII deficiency and hypofibrinogenemia. |
FFP; 80 units; 150-250 mg |
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RhIg is a solution of concentrated _____________, which is manufactured from pooled hyperimmunized donor plasma. It is used to prevent RhO (D) immunization of an unsensitized Rh-negative mother after an abortion, miscarriage, amniocentesis, or delivery of an Rh-positive and Rh-unknown infant. |
anti-RhO (D)
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One unit of random donor platelets typically increases the platelet count in a 70 kg-adult by ___________________/microliter. I unit of apheresis platelets should increase the platelet count in a 70-kg adult by ________________________/microliter. |
5,000 to 10,000/microliter; 30,000 to 60,000/microliter
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What is included in the physical examination at the donor center? |
General appearance; Weight: 10.5 mL/kg weight; if less than 100 lbs, blood and anticoagulant must be proportionally reduced; Temperature: less than or equal to 37.5 C or 9.5F; Pulse: 50-100 bpm; Blood pressure: systolic less than 180, diastolyic less than 100; Hemoglobin/hematocrit: 12.5/38%; Hemoglobin/hematocrit (autologous): 11/33%; Skin free of lesions |
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What are the disadvantages of using autologous blood? |
bacterial contamination, circulatory overload, cytokine mediated reactions and product/recipient misidentification |
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When does preoperative surgery collection take place? |
5-6 weeks prior |
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Describe acute normovolemic hemodilution |
concurrent collection and replacement with crystalloids to maintain normal blood volume |
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Directed donation |
same requirements as allogenic donors; unit directed toward a specific patient; if donor is a blood relative, unit must be irradiated to prevent GVHD |
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Irradiated RBCs |
expires 28 days after irradiation of original outdate (whichever is sooner); inhibits proliferation of T cells (GVHD); minimum gamma irradiation is 25 Gy to central part of bag |
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Platelet concentrates |
Random donor: 5.5 x 10^10 Apheresis: 3 x 10^11 |
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What is the minimum pH required for platelets? |
6.2 |
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What dose of RhIG would be appropriate for a D-negative woman who has had a miscarriage at 11 weeks gestation? |
50 ug |
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Which organism is responsible for transmitting Chagas disease? |
T. cruzi |
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FFP is the product of choice for patients with: |
TTP |
