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36 Cards in this Set
- Front
- Back
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An ABO type on a patient gives the following reactions: Cells: 4+ anti-A; 4+ anti-B Serum: Neg A1 cells; Neg B cells What is the patient's blood type? |
AB |
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The major immunoglobulin class of anti-B in a group A individual is: |
IgM |
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What are the possible ABO phenotypes of the offspring from the mating of a group A to a group B individual? |
O, A, B, AB
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What is the immunodominant sugar responsible for blood group A specificity? |
N-acetyl-D-galactosamine |
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What ABH substances would be found in the saliva of a group B secretor? |
H and B |
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An ABO type on a patient gives the following reactions: Cells: 4+ anti-A, 4+ anti-B, Neg anti-A1 Serum: 2+ A1 cells; Neg B cells These reactions may be seen in a patient who is: |
A2B with anti A1 |
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Which of the following ABO groups contains the least amount of H substance? A1B, A2, B, O |
A1B |
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You are working on a specimen in the laboratory that you believe to be a Bombay phenotype. What reactions would you expect to see? |
Patient's cells + Ulex europaeus = no agglutination |
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Name an example of a technical error that can result in an ABO discrepancy. |
Cell suspension too heavy |
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An ABO type on a patient gives the following reactions: Cells: 4+ anti-A, Neg anti-B Serum: 2+ A1 cells; 4+ B cells; 2+ O cells; Neg autocontrol These results are most likely due to: |
Non-ABO alloantibody |
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ABO frequencies: Group O: ____% Group A: ____% Group B: ____% Group AB: ____% |
Group O: 45% Group A: 40% Group B: 11% Group AB: 4% |
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ABO blood group system has naturally occurring antibodies that are primarily __________. |
IgM |
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ABO genes, like those of most other blood groups, are inherited in a __________________ manner |
codominant |
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ABH-soluble antigens are secreted by tissue cells and are found in all body secretions. The antigens secreted depend on: |
the person's ABO group |
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ABO reverse grouping is omitted from cord blood testing on newborns because: |
their titer levels are generally too low for detection |
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ABO RBC antigens can be glycolipids, glycoproteins, or glycosphingolipids; ABO-secreted substances are _______________. |
glycoproteins |
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_______________ is the most immunodominant sugar responsible for H-specificity. |
L-fructose |
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_______________ is the most immunodominant sugar responsible for A-specificity. |
N-acetylgalactosamine |
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_______________ is the most immunodominant sugar responsible for B-specificity. |
D-galactose |
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The hh genotype is known as the __________ phenotype, or Oh, and lacks normal expression of the ABH antigens. |
Bombay |
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Group _____ persons have the greatest amount of H substance and group __________ persons have the least amount of H substance. |
O; A1B |
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Approximately ____% of the individuals inherit the A gene phenotype as A1; the remaining inherit it as A2 or weaker subgroups. |
80% |
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Approximately 1% - 8% of A2 persons produce ________ in their serum. |
anti-A1 |
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Glycoproteins in secretions are formed on type ___ precursor chains. |
type 1 |
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The ABH antigens on RBCs are formed on type ___ precursor chains. |
type 2 |
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Forward and reverse grouping normally yield _______ reactions |
strong (3+ to 4+) |
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Group A persons have _________ in their serum |
anti-B |
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Group B persons have _________ in their serum |
anti-A |
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Group O persons have _________ in their serum |
both anti-A and anti-B |
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Group AD persons have _________ in their serum |
no anti-A or anti-B |
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Approximately 78% of random population inherit the _____ gene and are termed secreters; the remaining 22% inherit the ______ gene and are termed nonsecreters. |
Se; se |
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The _______ gene codes for the production of L-fucosyltransferase. |
Se |
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Name the blood type: Cells: 4+ anti-A; Neg anti-B; + anti-D Serum: Neg A1 cells; 4+ B cells |
A+ |
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Name the blood type: Cells: Neg anti-A; 4+ anti-B; Neg anti-D Serum: 3+ A1 cells; Neg B cells |
B- |
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Name the blood type: Cells: 4+ anti-A; 4+ anti-B; + anti-D Serum: Neg A1 cells; Neg B cells |
AB+ |
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Name the blood type: Cells: Neg anti-A; Neg anti-B Serum: 4+ A1 cells; 4+ B cells |
O |
