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40 Cards in this Set

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What is the standard deferral period between whole blood donations?

8 weeks (56 days)

The units of blood can be:

(blood/anticoagulant and preservative)




450 mL/63 mL or 500 mL/70 mL

What is the most commonly used anticoagulant/preservative?

CPDA-1

When do units preserved with CPDA-1 expire?

5 weeks (25 days)

When do units with additive solutions (AS) expire?

6 weeks (42 days)

What temperature are RBCs stored at?

1-6 degrees Celsius

What temperature are platelets stored at?

Room temperature (20-24 degrees Celsius) with continuous agitation.

For how long are platelets viable after collection?

5 days

An individual comes into the blood bank to donate blood. The nurse finds that he has a body temperature of 100.0 degrees Fahrenheit. Can he donate blood today?

No; the individual must have a body temperature less than or equal to 99.5 degrees Fahrenheit (37.5 degrees Celsius).

An individual comes into the blood bank to donate blood. The nurse finds that the potential donor has a systolic b.p. of 178 mm Hg and a diastolic b.p. of 98 mm Hg. Can he donate blood today?

Yes; the systolic b.p. must be less than or equal to 180 mm Hg and the diastolic b.p. less than 100 mm Hg.

An individual comes into the blood bank to donate blood. The nurse finds that he has a hematocrit level of 34%. Can he donate blood today?

No; the hematocrit must be greater than 38% if not an autologous donation.

An individual comes into the blood bank to donate blood. The nurse finds that he has a hemoglobin level of 13.5 g/dL. Can he donate blood today?

Yes; the Hgb must be greater than or equal to 12.5 g/dL.

An individual comes into the blood bank to make an autologous blood donation. The nurse finds that he has a hematocrit level of 36% and a hemoglobin level of 12 g/dL. Can he donate blood today?

Yes; for autologous donations, the Hgb must be at least 11 g/dL and Hct must be at least 33%.

What are some of the requirements for a male making a double red donation?

Height: at least 5'1"


Weight: at least 130 lbs


Hgb: at least 40%

What are some of the requirements for a female making a double red donation?

Height: at least 5'5"


Weight: at least 150 lbs


Hgb: at least 40%

How long is the deferment period after a double red donation?

16 weeks

A patient would like to donate blood, but she weights 105 lbs. Therefore the amount of blood collected and the amount of anticoagulant must be adjusted. What volume of blood could you collect and what volume of anticoagulant would you use?

Volume of blood to collect = (donor's weight in kg/50) x 450 = (48 kg/50) x 450 = 432




Reduced volume of anticoagulant = (volume to collect/450) x 63 mL = (432 mL/450) x 63 = 60.48mL




Amount of solution to be removed = 63mL - above calculated volume = 63 - 60.48 = 2.52 mL



What is the maximum volume of blood that can be collected from a 110 lb donor, including samples for processing?

525 mL

When RBCs are stored, there is a shift to the left. What does this mean?

Hemoglobin oxygen affinity increases, owing to a decrease in 2,3-DPG.

The majority of platelets transfused in the United States are:

apheresis platelets

Which anticoagulant preservatives provides a storage time of 35 days at 1-6 degrees Celsius for units of whole blood and prepared RBCs if an additive solution is not added?

CPDA-1

What is the minimum number of platelets required in a platelet concentrate prepared from whole blood by centrifugation?

5.5 x 10^10

For how long can RBCs be frozen?

10 years

What is the minimum number of platelets required in an apheresis component?

3 x 10^11

One criterion used by the FDA for approval of new preservation solutions and storage containers is an average 24-hour post transfusion RBC survival of more than:

75%

What is the lowest allowable pH for a platelet component at outdate?

6.2

Frozen and thawed RBCs processed in an open system can be stored for how many days/hours?

24 hours

What is the hemoglobin source for hemoglobin-based oxygen carriers in advanced clinical testing?

Both bovine and human hemoglobins

What happens to the pH level during the storage of RBCs?

The pH decreases

Nucleic acid amplification testing is used to test donor blood for which infectious disease(s)?

Hepatitis C, HIV, and West Nile Virus.




As of 2011, samples from donors of each unit of donated blood are tested by 10 screening tests for infectious disease markers.

What are some FDA approved tests for quality control of platelets?

BacT/ALERT, eBDS and PGD test.

Prestorage pooled platelets can be stored for how long?

5 days

What is the most common cause of bacterial contamination of platelet products?

Entry of skin plugs into collection bag

What generates the ATP needed by RBCs?

Glycolysis (90%), pentose phosphate pathway (10%)

When do units preserved with ACD, CPD, or CP2D expire?

3 weeks (21 days)

RBCs have been traditionally glycerolized and frozen within ____ days of whole blood collection in CPD or CPDA-1 and can be stored ____ years from the date of freezing.

6 days; 10 years

What is the FDA approved rejuvenation solution used in some blood banks to regenerate ATP and 2,3-DPG levels before RBC freezing?

Rejuvesol

Rejuvenation is used primarily to salvage ___-type and rare RBC units that are outdate or with specific anticoagulant-preservative solutions up to ___days past outdate.

O-type; 3 days

When platelet concentrates are pooled using an open system, the storage time changes to ____ hours. A new method of pooling that uses a closed system allows the pool to be stored for ___ days from the date of collection.

4 hours; 5 days

If a platelet bag is broken or opened, the platelets must be transfused within ____ hours.

4 hours.