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35 Cards in this Set
- Front
- Back
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b-cells
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mature in bone. use antibodies. third line of defense.
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T-cells
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mature in thymus. third line if defense.
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1st line of defense
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Barrier. anatomical and physiological structures and chemicals. epithelial layers
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2nd line of defense
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sentry and protective. recognition of foreign vs. self destruction of foreign substances. macrophages
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3rd line of defense
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B and T Cells. acquired. has a memory. developed in unique response to microbial PAMPS interaction with W.B.C.
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PAMPS
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Pathogen Associated Molecular Patterns
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connective tissues
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monitored by macrophages
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lymphatics
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lymph and drain off
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whole blood
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blood cells and plasma
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lysozymes
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tears and saliva
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Mucosal (MALT)
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coats and removes. cilia to move mucosal debris
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Difinions
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(cationic peptides) inhospitable ph
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opsonization
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stimulates macrophages
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T1
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cytotoxic killers (viruses)
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TH1
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stimulates B cells to opsonization
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TH2
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stimulates B-cells to neutralization.
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Mast Cells
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histamine
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adult pluripotent stem cells in the _____ ______ will generate either RBC WBC or platlets.
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bone marrow
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Granulocytes
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prominent granules and lobular nucleus.
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neutrophils
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55-90% of circulating- phagocytosis- geared to bacteria
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Eosinophils
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1-3% of circulating- specialized-geared to parasites
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Basophils
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.5% of circulating-release of histamine-geared towards allergies
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spleen
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filter for blood, removes old red blood cells and pathogens
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Thymus
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incubator for T cells. (thymoscytes) prominent after birth through puberty afterwards shrivels.
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rudor
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red inflammation
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calor
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heat
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tumor
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swollen
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dolar
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pain
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damaged cells release _______ and________
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chemicals and cytokines
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Serous fluid
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clear
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pus
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cell debris from phagocytosis
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first line of defense
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innate, non specific, physical barriers, chemical barriers, genetic barriers.
ia surface protection composed of anatomical and physiological barriers that keep microbes from penetrating sterile body compartments. |
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second line of defense
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innate, nonspecific. includes inflammatory response interferons phagocytosis and complement.
acellular and chemical system that comes immediately into play if infectious agents make it past the surface defenses. |
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third line of defense
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can either be naturally acquired or artificially acquired. it can be naturally acquired actively by infection or passively by maternal antibodies. It can be acquired artificially actively by vaccination or passively by immune serum.
include specific host defenses that must be developed uniquely for each microbe through the action of specialised white blood cells. This form of immunity is usually long term and has memory |
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cation
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positively charged
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