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4 Cards in this Set
- Front
- Back
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Infective Endocarditis |
Diagnosed by Modified Duke Criteria which includes an echocardiogram, allowing for visualization Most common organisms IE are staph., strept., and enterococcus |
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Empiric treatment |
Vancomycin and ceftriaxone 4-6 weeks of IV antibiotic treatment is required |
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Gentamicin |
Gentamicin is added to primary antimicrobial therapy for synergy when feasible for more difficult infections to eradicate such as prosthetic valve infections Duration of gentamicin varies based on the presence of prosthetic valve (2 weeks) or pathogen (4-6 weeks) When gentamicin is used for synergy, target peak levels of 3-4 mcg/mL and trough levels<1mcg/mL. Extended interval dosing is not used for AMG when treating endocarditis Rifampin - used in cases of staph prosthetic valve endocarditis due to its ability to treat organisms in a biofilm |
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IE Dental Prophylaxis |
PROPHYLAXIS!! Given as a single dose 30-60 min dental procedure oral: --Amoxicillin 2 grams If allergic to penicillins: --Cephalexin or cefadroxil 2 grams --Clindamycin 600 mg --Azithromycin or clarithromycin 500mg |
