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8 Cards in this Set
- Front
- Back
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What does the drug acylcloguanosine do? |
It is a deoxyguanosine analogue Competes with GTP leading to chain termination Used for herpes virus Is thymidine kinase or DNA polymerase mutates then it will be ineffective. Lacks 3' hydroxyl |
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Maraviroc |
Used in HIV therapy Inhibits attachment Blocks Co-receptor binding (CCR5) |
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Efurvitide |
HIV inhibition of fusion of envelope with cell membrane Peptide inhibitor binds to gp41 subunit of hiv envelope glycoprotein |
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Azidothymidine |
HIV inhibition of reverse transcriptase Nucleoside analogue inhibitor |
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Nevaripine |
Non nucleoside HIV RT inhibitor Bind to RT near to polymerase active site which becomes distorted |
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Saquinavir |
Inhibits enzyme that cleaves polyprotein to produce viral structural proteins - HIV |
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Amantadine |
Blocks M2 receptors on influenza virus |
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Ribavirin |
Nucleoside analogue used to treat Hep C |
