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8 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Type I Hypersensitivity
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Ig-E mediated
pollens, drugs, foods, insect venom, animal dander |
allergic rhinitis (hay fever), eczema, hives, allergic gastroenteropathy, asthma
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Type II Hypersensitivity
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antibody-mediated cytotoxicity
blood antigens, Rh antigens, drugs that change host tissue, infectious agents, molecular mimicry, autoimmunity |
transfusion, erythroblastosis fetalis, rheumatic fever, drug reactions, Goodpasture's syndrome, Drug-induced lupus, SLE
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Type III Hypersensitivity
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immune complex deposition
drugs, vaccines, inhaled antigens (fungus) |
arthus reaction, serum sickness, post-streptococcal glomerulonephritis, RA, SLE
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Type IV Hypersensitivity
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cell-mediated
delayed type: poison ivy, poison oak, soaps, transplanted tissue T-cell mediated cytotoxicity: transplanted or virus-infected cells and tissues |
delayed type: dermatitis, acute graft rejections, PPD skin test
T-cell mediated cytotoxicity: acute graft rejection, viral infections, neoplasia |
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Hyperacute rejections
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preformed antibodies bind to antigen on tissue
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Type II
minutes to hours |
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Acute rejection
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memory T cells recognize antigen; CD8s destroy graft
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Type IV (T cell mediated cytotoxicity)
days to months |
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chronic rejection
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antibodies develop over time, and damage graft vasculature
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Type II, III
months to years |
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Graft vs. Host
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T cells in transplanted tissue attack host
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Type IV (T cell mediated cytotoxicity)
days to weeks |
