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130 Cards in this Set
- Front
- Back
All or None Law
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neuron either generates an action potential or it does not
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myelinization
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axon that has schwann cells
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saltatory conduction
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increases rate that impulse travels
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rate of conduction is influenced by:
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myelinated over non myelinated and diamater (the thicker the axon the faster the rate)
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multipe sclerosis
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auto immune disease that destroys myelin
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polaraization
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there is a seperation of electrical charges
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depolarization
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membrane potential is reduced, moves to a more positive inside
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repolarization
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membrane returns to the RMP after depolarization
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hyperpolarization
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becomes less than -70
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graded potential
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short lived local changed in the membrane that can either be depolarizing or hyperpolarizing
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action potential
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cells with excitable membranes
ex: neurons and muscle cells |
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normal neural pathway
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receptor, afferent neuron, interneuron, efferent neuron, effector
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decremental
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decreases in magnitude as it moves down
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What happens during membrane potential?
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changes membrane permiability ions to move through in or out
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What happens at rest during membrane potential?
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sodium ion channels close, potassium ion channels open
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Why does this happen during membrane potential?
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voltage gated channels, some protein channels are chemically gated, and mechanically gated channels respond to stretch
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temporal summation
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summation over time
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spatial summation
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summation over space
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convergence
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comes together, nerve impulses converge on post synaptic axon hillock
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divergence
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influences many other cells, one nerve sends to many others
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AchE
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acetylcholinesterase
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muscarinic and nicotinic
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bind to acetylcholine
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serotinin
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regulator of mood and behavior
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ligand operated channel
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nictonic receptor, 5 polypeptide structure opens by binding 2 ACH
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G protein operated channel
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muscarinic receptons: Alpha, beta, gamma complex, one protein is receptor trigger
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schwann cells
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form myelin sheath around axons
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satellite cells
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around cell bodies, take care of unipolar neurons
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oligodendrocytes
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makes myelin (increase rate of conduction)
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microglia
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carry on phagocytes
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ependymal
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line brain ventricles and spinal cord
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astrocytes
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largest neurooglial cell, star shaped
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function of astrocytes
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nurse cells, pick up neurotransmitters, blood brain barrier, control ion concentration with in extracellular fluid
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organization of the nervous system
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one fully integrated system with divisions based on differences in structure, location, and function
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CNS
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brain and spinal cord
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brain
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high demand of food and oxygen
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brain protection
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bone, glial cells, meninges, CSF, BBB
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meninges
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Dura mater
arachnoid mater subarachnoid mater pia mater |
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CSF- circulatory system
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circulatory
cushion buoyancy |
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BBB
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no pores b/w cells, nonpolares move in and out, polars have carriers
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plasticity
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ability to re model
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sulci
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grooves
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gyri
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ridges
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corpus callosum
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connection b/w 2 hemispheres
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occipital lobe
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posterior, sight
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temporal lobe
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side, sound and memory storage of auditory and visual info
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parietal lobe
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somatoesthetic sensation (hot, cold)
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post central gyrus
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map of body regions
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wernicke's area
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lauguage comprehension
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frontal lobe
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voluntary motor, gives ability to speak, elaborate thinking, personality
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precentral gyrus
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motor areas
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broca's area
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speaking ability
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insula
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deep behind temporal lobe at posterior end of lateral sulcus, memory
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left hemipshere
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good at verbal tasks, math, language, logical thinking
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right hemisphere
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artisitic and musical
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basal nuclei
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gray matter located deep with in cerebral white matter
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EEG-electroencephalogram
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clincical tool, distinguish different stages of sleep, legal tool
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short term memory
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only for seconds, limited storage, no permenant structural changes in brain
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long term memory
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gets infro from short term, unlimited storage, permenant structural changes in brain
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diencephalon
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brain tissue found underneath cerebrum
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thalamus
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relay station, gathers info and sends it to where it needs to go
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hypothalamus
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the tie between the nervous system and the endocrine system
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hypothalamus functions
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controls body temp, controls thirst and urine output, controls hungar, controls pituitary secretions, indirect control of cardiac output, play a role in emotional and behavioral patterns
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pons
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respiratory control
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cerebellum
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contributes to maintenance of balance, enhances muscle tone, coordinated skilled voluntary movement
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brainstem functions
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acending and descending nerve tracts, direct control of cardiovascular and respiratory system, reflexes, sleep center, cranial nerves
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NREM
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non rapid eye movement, slow wave sleep
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REM
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rapid eye movement, paradoxial sleep
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narcolepsy
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fall asleep randomly
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insomnia
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decreased quantity and quality of sleep
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limbic system
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a ring of forebrain structures that surround the brain stem, center from emotional drives
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RAS- reticular activating system
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alert, awake, sleep, coma, dead
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dorsal root
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afferent, incoming info
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ventral root
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efferent, outgoing info
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spinal nerve
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both dorsal and ventral root fibers (afferent and efferent)
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dorsal root ganglion
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contain cells bodies of afferent neurons
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reflexes
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unconcious motor response to a sensory stimulus
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simple reflex
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happens automatically
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acquired reflex
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learned something
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reflex arc
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receptor, afferent pathway, integrating center, efferent pathway, effector
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sympathetic
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thoracolumbar, fight or flight
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parasympathetic
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cranial sacral division
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dual innervation
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input coming from parasypathetic and sympathetic
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antagonistic effects
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oppostie
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complimentary effects
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both produce similar effects
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cooperative
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both systems work together to promote a single action
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adrenergic
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epinepheron and norepinepheron
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cholinergic
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acetylcholine, can be excitatory or inhibitory
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tonic
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slow or no adapting
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phasic
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quickly adapting
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afferent input
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sensory info
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perception
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consious interpretation of external worls as created by the brain from a pattern of nerve impluses
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adequate stimuli
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usual specialized stimulus a receptor uses
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alternative stimuli
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mechanical stimulation
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types of receptors
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thermoreceptors (heat), photoreceptors (light), mechanorecptors (sound), nocireceptors (pain)
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phantom pain
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amputated people have pathways from their foot even if they don't have one
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receptive field
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scribed area for which it is responsible for. more receptors in a region- smaller the field size
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skeletal muscle
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voluntary, striated, multi nucleated, contract and relax rapidly
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smooth muscle
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involuntary, non striated, one nucleus, contracts and relaxes slowly
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cardiac muscle
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involuntary, striated, one nucles (2), intercallated discs
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motor unit
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one motor neuron plus all the muscle fibers it innervates
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motor unit recruitment
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greater strength or force of contraction
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temporal summation
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TTT- time, temporal, tetenus
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optimal length
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the maximum tension that can be developed when a contraction occurs
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origin
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attachment to the most stationary part of the skeleton
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insertion
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attachment to the most moveable part of skeleton
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isotonic contraction
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sane tension, muscle changes
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isometric contraction
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same length, muscle is prevented from shortening
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ATP is required for:
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power stroke of cross bridge, detach myosin from actin, pump calcium ions back into sarcoplasmic reticulum
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glycolysis
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high intensity, short duration
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creatine phosphate
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donate phosphate to make a new one
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oxidative phosphorylation
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gets everything back to original state
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regular aerobic exercise:
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increase number and size of mitochondria, ATP production, myoglobin content, fat burning, number of circulatory pathways, and decrease of lactic acid production
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hypertrophy
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increase in muscle size
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atrophy
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muscle decreases in size
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red slow twitch fibers (oxidative)
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large quantities of myoglobin, a lot of O2 and mitochondria, aerobic respiration, doesnt tire quickly, contracts and relaxes slowly
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white fast twitch fibers (glycolytic)
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no myoglobin, no O2 and not a lot of mitochondria, anaerboic respiration, contracts and tires rapidly
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red fast twitch (intermediate)
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myoglobin, O2 and mitochondria, aerobic, contracts rapidly
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What muscle fibers would be in you arm?
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white fast twitch
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What muscle fibers would be in your lower back?
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red slow twitch
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What muscle fibers would be in your legs?
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red fast twitch
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Similarities to skeletal muscle:
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all have actin and myosin, all contract in response to calcium, all use ATP for crossbridges
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Differences of skeletal muscle:
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structure and organization of fibers, mechanisims of excitation, excitation/contraction coupling
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smooth muscle
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no sarcomere units, troponin, or tropomyosin
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Calcium ion
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does not cause a physical change, causes a chemical reaction, that causes phosphorylation of myosin, so myosin can bind to actin and work
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muli-unit smooth muscle
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neurogenic, functions like skeletal muscle but innervated by autonomic neurons
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single-unit smooth muscle
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functional syncytium, cells which work as a unit mechanically and electrically
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pineal gland
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part of epithalamus, make melatonin hormone
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choroid plexus
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part of epithalamus, produces cerebral spinal fluid
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ADH
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anti diretic hormone, decrease urine production
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oxytocin
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uterine contraction during child birth
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