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69 Cards in this Set
- Front
- Back
what are the functions of blood
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transport, regulate body temp, protect againt blood loss by mediating clotting, blood is a connective tissue
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what does blood transport
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oxygen from the lungs to the body, and CO2 from the body to the kidneys
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what is the fluid that remains after a clot is formed
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serum
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what percent of plasma is water and what does plasma contain
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92% water, contains ions, nutrients, wastes and hormones
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what are the 3 main plasma proteins that are formed in the liver
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albumin, globulin, fibrinogen
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albumin
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gives blood viscosity
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globulin
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transporters (hemoglobin) or antibodies (immunoglobins)
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fibrinogen
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element of coagulation (clotting)
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erythrocytes are what
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red blood cells (RBC)
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what is the purpose of erythrocytes
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to transport oxygen and CO2 throughout the body
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where does the exchange of gases occur in the body
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in the capillaries of the lungs and in the capillaries in the peripheral tissues
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hemotocrit
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RBC vol / total cell vol * 100%
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what are some characteristics of erythrocytes
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biconcave disc, no nucleus, lives only for 120 days, travels 700 miles during the 120 days
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erythropoiesis
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production of RBC which occurs in the red bone marrow, stimulated by the hormone erythropoietin (produced in the kidneys)
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is bone marrow found in all bones
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yes
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what are the two types of bone marrow
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red and yellow
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what is the function of red bone marrow
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to actively generate blood cells
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at birth is all bone marrow red
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yes
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what is the yellow color of yellow bone marrow from
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fat
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can yellow bone marrow become red bone marrow if needed
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yes
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in adults where is yellow bone marrow found
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in long bones (tibia, fibula, radius, ulna)
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where is red bone marrow found
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in the proximal ends of the proximal long bones (pelvis, vertebrae, sternum, ribs, skull, scapula)
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what percent of hemoglobin is in RBC's
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97%
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hemoglobin
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an oxygen carrying protein
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what give RBC's their red color
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oxidation of the iron in blood
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dead red blood cells are recycled by what and in where
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macrophages, in the spleen
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glycoproteins and glycolipids
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surface antigens on cell membranes of all cells
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what are the 3 important surface antigens
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A, B and D (Rh factor)
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if a blood transfusion is given w/ imcompatible blood, what occurs
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clumping can occur which causes the cells to hemolyze (rupture)
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type A blood
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40% population, has type B antibodies present in plasma, can receive type A and O RBC's
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type B blood
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10% population, has type A antibodies present in plasma, can receive type B and O RBC's
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type AB blood
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4% population, has no antibodies present in plasma, can receive type A, B and O RBC's, universal recipient
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type O blood
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46% population, has type A and B antibodies present in plasma, can receive type only type O RBC's, universal donor
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Rh positive
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has the D antigen present on the RBC, has no anti-D antibodies present in the plasma
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Rh negative
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does not have D antigen present on the RBC, produces anti-D antibodies in plasma when exposed to D antigens
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leukocytes
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white blood cells (WBC)
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are leukocytes complete cells w/ a nucleus and organelles
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yes
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where do WBC's function
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outside of the blood vessles in the connective tissue
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chemotaxis
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move toward a site by following chemical attractants
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diapedesis
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move into the tissues through small openings between the endothelial cells of capillaries and post capillary venules
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what does increase WBC's in a blood sample indicate
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an infection
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how are leukocytes classified as
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either granular or Agranular (no granules)
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neutrophils (granular leukocytes)
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nucleus contains 2-6 connected lobes, most abundant, defence against bacterial infection, first line of defense, think macrophage/scavenger or phagocyte of blood, granules are digestive enzymes to digest bacteria
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eosinophils (granular leukocytes)
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loves red, nucleus has two lobes connected, granules stain red, fight parasite infections, mediate allergic reactions, and phagocytosis of antigen/antibody complexes, granules contain digestive enzymes
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basophils (granular leukocytes)
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loves blue, nucleus has 2 lobes connected in a U or S shape, granules stain dark purple, release histamine during allergic reaction, function is similar to mast cells found in tissue
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monocytes (Agranular leukocytes)
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nucleus is dark and kidney, horse-shoe or U shaped, precursor to the macrophage but found in the circulatory system
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lymphocytes (Agranular leukocytes)
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nucleus is dark, round and large, major component of immune system, immune attach cells are the T and B lymphocytes
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where are lymphocytes produced
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in bone marrow
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where are B lymphocytes educated
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bone marrow
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where are T lymphocytes educated
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thymus
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B lymphocytes
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stimulated agains an antigen, become plasma cells and make antibodies against the antigen
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do antigen-antibody complexes get phagocytoed by macrophages
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yes
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T lymphocytes
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T helper cells and T cytotoxic cells
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T helper cells
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help to stimulate B lymphocytes and T cytotoxic lymphocytes
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T cytotoxics are what
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cell killers
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platelets (also called thrombocytes)
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not actual cells, are disc shaped fragments enclosed by a plasma membrane, derived from megakaryocytes
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embolism
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blockage
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thrombus
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narrowing of an artery
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mnemonic for remembering the blood cells from Most to Least frequent in circulating blood
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Remember Please, Never Let Monkeys Eat Bananas (RBC>Platelets>Neutrophils>Lymphocytes>Monocytes>Eosinophils>Basophils)
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anemic
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low hematocrit or RBC count
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bacterial infection
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high neutrophils
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parasite infection or allergies
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high eosinophils
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hematopoiesis
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blood cell formation, occurs in bone marrow, continuous throughout life
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all blood cells originate from what
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stem cells
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myeloid stem cells
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form all other blood cells
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lymphoid stem cells
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form lymphocytes
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reticulocyte
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immature RBC
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myeloid stem cells differentiate into what
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megakaryotes
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megakaryotes produce what
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platelets
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