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17 Cards in this Set

  • Front
  • Back

Human Growth Hormone (hGH)- Hyposecretion

Pituitary dwarfism- low hGH during childhood, epiphyseal plates close before normal height is reached

Human Growth Hormone (hGH)- Hypersecretion

Giantism- high hGH during childhood is acromegaly


High hGH during adulthood: hands+feet enlarged, skin gets coarse, thickened lips, tongue, nose+ear, drooping lower jaw, furrowed brow

Prolactin (PRL)

Hypersecretion causes galactorrhea and amenorrhea

Sheehan's Syndrome

Postpartum hypoptuitarism


Loss of blood during childbirth, ischemic necrosis, and hypovolumic shock

Antidiuretic hormone (ADH)- Neurogenic Diabetes Insipidous

Head trauma, damage to posterior pituitary/hypothalamus, brain tumor, inability to secrete antidiuretic hormone

Antidiuretic hormone (ADH)- Nephrogenic Diabetes Insipidus

Damage to kidneys, ADH receptors

Thyroid Hormone- Goiter

Enlarged thyroid gland


Endemic goiter- nutritional deficiency of iodine, hypersecretion of TSH

Thyroid hormone- cretinism

Hypothyroidism during fetal life+infancy


Normal at birth


Stunted growth


Severe mental retardation

Thyroid hormone- Myxedema

Hypothyroidism in adulthood


Puffy face


Baggy eyelids


Swollen hands+feet


Constipation


Weight gain


Low body temp


Slow heart rate


Memory loss


Seen more women

Thyroid hormone- hypermetabolic state

Hyperthyroidism


Intolerant to heat


Weight loss


Tachycardia


Palpitation


Hypertension


Warm moist skin


Profuse sweating

Thyroid gland- Graves disease

Enlarged thyroid


Exophthalamus: edema behind eyes


Higher on monozygotic twins


Emotional influences


More among women

Cortisol-Hypersecretion: Cushing's syndrome

Spindly limbs- buffalo hump


Rounded flush moon face


Pendulous abdomen


Hypertension


Mood swings


Infections

Cortisol+Aldosterone- Hyposecretion: Addison's disease

Nausea, vomitting


Hypoglycemia


Weight loss


Anorexia


High K+, Low Na+


Low BP


Bronzing of skin

Cortisol blocked: Virilism

High ACTH due to lack of negative feedback


Masculization of females


Premature puberty


Adult women w/enlarged clitoris


Atrophied breast, male physique


Adult men get gynecomastia-feminized adenoma

Adrenal Medulla: Pheochromocytoma

Tumor of chromaffin cells


Episodes of fight or flight response

Pancreas: Type I Diabetes

Previously known as insulin dependent diabetes mellitus


Immune system destroys pancreatic beta cells


Must have insulin injections


Frequent in children and young adults

Pancreas: Type II Diabetes

Non-insulin dependent diabetes mellitus


Much more common than type I


Begins as insulin resistance


Pancreas loses ability to produce insulin