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17 Cards in this Set
- Front
- Back
Human Growth Hormone (hGH)- Hyposecretion |
Pituitary dwarfism- low hGH during childhood, epiphyseal plates close before normal height is reached |
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Human Growth Hormone (hGH)- Hypersecretion |
Giantism- high hGH during childhood is acromegaly High hGH during adulthood: hands+feet enlarged, skin gets coarse, thickened lips, tongue, nose+ear, drooping lower jaw, furrowed brow |
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Prolactin (PRL) |
Hypersecretion causes galactorrhea and amenorrhea |
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Sheehan's Syndrome |
Postpartum hypoptuitarism Loss of blood during childbirth, ischemic necrosis, and hypovolumic shock |
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Antidiuretic hormone (ADH)- Neurogenic Diabetes Insipidous |
Head trauma, damage to posterior pituitary/hypothalamus, brain tumor, inability to secrete antidiuretic hormone |
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Antidiuretic hormone (ADH)- Nephrogenic Diabetes Insipidus |
Damage to kidneys, ADH receptors |
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Thyroid Hormone- Goiter |
Enlarged thyroid gland Endemic goiter- nutritional deficiency of iodine, hypersecretion of TSH |
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Thyroid hormone- cretinism |
Hypothyroidism during fetal life+infancy Normal at birth Stunted growth Severe mental retardation |
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Thyroid hormone- Myxedema |
Hypothyroidism in adulthood Puffy face Baggy eyelids Swollen hands+feet Constipation Weight gain Low body temp Slow heart rate Memory loss Seen more women |
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Thyroid hormone- hypermetabolic state |
Hyperthyroidism Intolerant to heat Weight loss Tachycardia Palpitation Hypertension Warm moist skin Profuse sweating |
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Thyroid gland- Graves disease |
Enlarged thyroid Exophthalamus: edema behind eyes Higher on monozygotic twins Emotional influences More among women |
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Cortisol-Hypersecretion: Cushing's syndrome |
Spindly limbs- buffalo hump Rounded flush moon face Pendulous abdomen Hypertension Mood swings Infections |
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Cortisol+Aldosterone- Hyposecretion: Addison's disease |
Nausea, vomitting Hypoglycemia Weight loss Anorexia High K+, Low Na+ Low BP Bronzing of skin |
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Cortisol blocked: Virilism |
High ACTH due to lack of negative feedback Masculization of females Premature puberty Adult women w/enlarged clitoris Atrophied breast, male physique Adult men get gynecomastia-feminized adenoma |
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Adrenal Medulla: Pheochromocytoma |
Tumor of chromaffin cells Episodes of fight or flight response |
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Pancreas: Type I Diabetes |
Previously known as insulin dependent diabetes mellitus Immune system destroys pancreatic beta cells Must have insulin injections Frequent in children and young adults |
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Pancreas: Type II Diabetes |
Non-insulin dependent diabetes mellitus Much more common than type I Begins as insulin resistance Pancreas loses ability to produce insulin |