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29 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
NRTI's class effect

(ZELDAS T)
BBW: lactic acidosis, heptamegaly, peripheral nueropathy, pancreatis, lipoatrophy, myopathy, anemia

HLpA

Hepatotoxic/hepatic steatosis
Lactic Acidosis/ lipo-atrophy/ lipohypertrophy
pAncreatisis
Abacavir coments
HLA B*5701 alle

next slide= SIDE EFFECTS
RASH, cardio vascular
DIDANOSINE comments
take on empty stomach

next slide= side efftecs
BBW
pancreatitis

S/E

eye exam
Emtricitabine comments

Brand?

Strorage?
brand = emtriva

comments may keep solution at RT for 3 months
BBW
may exacerbate hep B

S/E
hyperpigmentation
Lamuvidine
Brand?
brand= epivir

S/E next page
BBW
dont use Epivir HBV for HIV
Stavudine storage

S/E ?
store in fridge for up to 30 days
side effects?
insulin resistance
Zidovudine

Brand ?
brand = retrovir

Side effects/ warnings next page
BBW
hematologic toxicites

insulin resistance
TENOFOVIR
BRAND?
brand= viread

BBW / side effects next page
BBW
Hep B exacerbation

nephrotoxocity
Atripla administration

Individual agents?
administer on empty stomach at HS

agents of atripla?
Emtricitabine (emtriva)
tenofovir (viread)
efavirenz (sustiva)
trizvir components
abacavir (ziagen)
lamuvidine (epivir)
ziduvidine (retrovir)
truvada agents?
tenofovir (viread)
emtricitabine (emtriva)
epzicom and combivir agents
Epzicom
abacavir (ziagen)
lamuvadine (epivir)
combivir
lamuvadine( epivir)
zidovidine( retrovir)
NRTI's renal adjustments?
yes
all execept
Ziagen
NNRTI's

Class effects
(NEED)
nevaripine
etravarine
efavirenz (sustiva)
dalaviridine

Effects
RASH
Hepatotoxic
Efavirinez S/E
vivid dreams
tetrogenic

TAKE ON EMPTY STOMACH AT HS
Protease Inhibitors

CYP enzyme?
all end with avir exept tenofovir and abacavir


3A4 Inhibitors
PI class effect

HGC
HGC
hyperlipidemia
G/I
cardio/ cerebro vascular
PI's that need boost
Less STD's

lopinovir/ritinovir (kaletra)
Saquinavir
tipranivir
darunavir(prezista)

also reyataz( atazanavir)
entry inhibitor

route of admin
efuvirtide (fusion)

SC admin
ritonavir storage/ comments
store in refridgerator
may keep at RT for 30 days


take with food
Kaletra coments
take with food
may store at RT
CCR5 Antag
maraviroc (selzentry)
Intergrase inhibitor
Raltegravir (isentress)
prefered regimens
2 NRTI's
1 NNRTI

(atripla)

alternatives
2 NRTI's (truvada)+ PI (reyataz or darunavir)
or
2 NRTI's(truvada) + Integrase inhibitors
pregnant preffered regimen
Kaletra + truvada

kaletra dosed BID
PCP tx
Bactrim DS
1 tab QD
Toxoplasmasa
Bactim DS
1 tab QD
Mycobacterium avium complex
MAC
Azithromycin
1200 mg qwk
mycobacterium TB
INH 300mg + b6 50mg QD for 9 months