Histology: Unit 8

Front 1

Identify the tissue/organ and the structures indicated

Back 1

Infundibulum (of oviduct). The right arrows indicate the fimbriae and left arrows indicate the mucosal folds (near ampulla region).

Front 2

Describe the composition of the fimbriae?

Back 2

Loose connective tissue core, some smooth muscle, lined by mucosal epithelium.

Front 3

Identify the tissue/structure? What kind of epithelium is present? Identify the cells indicated with arrows?

Back 3

Mucosal folds in the oviduct; Mucosal epithelium is simple columnar. Central lamina propria. Left arrows indicate secretory (aka peg) cells; Right arrows indicate ciliated cells (note they rest on basal bodies).

Front 4

What effect does estrogen have on the ciliated and secretory (peg) cells?

Back 4

Estrogen stimulates both cell types to hypertrophy. It stimulates elongation of the cilia, and promotes increased secretion. Loss of estrogen reverses these effects.

Front 5

Back 5

Front 6

Back 6

Front 7

Back 7

Front 8

Back 8

Front 9

Back 9

Front 10

Back 10

Front 11

Back 11

What cell layer is not found in thin skin? Stratum lucidum

Front 12

Identify the tissue and structures denoted by thin arrows. What pathological structure is indicated by the thick arrow?

Back 12

Breast-Inactive mammary gland; Main features: parenchyma is mainly duct elements. Stroma (in lobule) is loose CT. Interlobular stroma is DICT. Top arrow-intralobular stroma; Bottom arrow-interlobular stroma (aka extralobular stroma); Pathology: macrocyst;

Front 13

Identify the structures indicated in this section of mammary tissue? Is it active or inactive? What type of epithelium is characteristic of this glandular epithelium?

Back 13

Myoepithelial cell (triangle shaped nuclei); Duct epithelial cell; This tissue is inactive. Simple cuboidal to low columnar epithelial cells characterize this tissue.

Front 14

True or false: in the inactive mammary gland, alveoli are present?

Back 14

False. There are no alveoli in the inactive mammary gland.

Front 15

Describe the changes in the mammary gland during the first half of pregnancy. What hormones are responsible for these changes?

Back 15

-Proliferation of intralobular ducts; Mammary tissue darker (basophilic) and looks more "crowded" with duct elements.
-Formation of end buds that hollow out to form alveoli.
-You will also see some mitotic figures
-Estrogen is main hormone required for duct and alveolar growth.

Front 16

Describe the changes in the mammary gland during the second half of pregnancy. What hormones are responsible for these changes?

Back 16

The alveoli differentiates and fat and protein droplets appear in alveolar cells. In some alveoli you may see a characteristic "apocrine snout." You will also see fat accumulation in the apical cytoplasm. Overall appearance is really crowded lobules that have an almost "squished" appearance. The intralobular stroma is highly vascularized the epithelium is often tall columnar. Progresterone is the main hormone needed for alveolar differentiation.

Front 17

Back 17

What features are present that are NOT typical of a human lactating mammary gland? Adipose tissue among the lobules.

Front 18

Back 18

Front 19

Describe the parenchyma and stroma of the inactive breast.

Back 19

Parenchyma is mostly duct elements whereas the stroma is loose connective tissue.

Front 20

What is the medical importance of the terminal duct lobular unit?

Back 20

It is the site from which most breast cancer arises.

Front 21

What is the difference breast secretion of mil proteins and milk lipids?

Back 21

Milk protein is secreted by merocrine secretion. Milk lipids are secreted by apocrine secretion.

Front 22

What is the primary function of colostrum?

Back 22

It provides the baby with passive immunity--it has a high concentration of antibodies and proteins.

Front 23

Identify the organ and structures indicated by the arrows.

Back 23

Ovary; Ovarian follicles

Front 24

Identify the organ and round structures in the foreground.

Back 24

Ovary; these are primordial follicles.

Front 25

Identify the structures indicated. What features help you make this identification.

Back 25

Two unilaminar primary follices; one developing multilaminar primary follicle.

Front 26

What follicle type is this? Describe features that help make this ID?

Back 26

Multilaminar primary follicle; stratified cuboidal epithelium (aka granulosa); NO fluid filled antrum; zona pellucida

Front 27

What follicle type is this? Describe features that help make this ID?

Back 27

Secondary follicle; stratified cuboidal epithelium (aka granulosa), fluid filled antrum; zona pellucida;