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76 Cards in this Set

  • Front
  • Back
Simple Squamous Epithelium
Stratified Squamous
Simple Cubodial
Stratified Cubodial
Simple Columnar
Stratified Columnar
Ciliated Pseudostratified Columnar
Transitional epithelium
secretory product is released in apical portion of cell surrounded by a thin layer of cytoplasm and plasma membrane
Aprocrine gland
secretory product accumulates within maturing cell, and is released into lumen of the gland when the cell undergoes apotosis.
holocrine gland
layer of variable thickness next to the basal surface
basement membrane
anchors the cell to extracellular matrix
Cell-to-extracellular matrix junctions
increase surface area & facilitates morphologic interations between adjacent cells
Plasma membrane inflodings
Ectoderm derivatives
- Epidermis
- Cornea & Lens
Enamel
Components of Inner Ear
Anterior Lobe of Pituitary
Mesodermal derivatives
Epithelium of Kidney & Gonads
Mesothelium (epithelium lining the pericardial, pleural, and peritoneal cavites)
Endothelium (epithelium lining the cardiovascular and lymphatic vessels)
Adrenal Cortex
Seminiferous & Genital duct epithelium
Endodermal derivatives
Respiratory System Epithelium
Alimentary Canal Epithelium
Extramural Digestive Gland Epithelium
Epithelium of tympanic cavity & auditory tubes
Types of anchoring junctions
zona adherens and macula adherens
Communicating junctions
Direct communication by diffusion of small molecules (gap junctions)
Occluding junctions
Impermeable (tight junctions)
specialized site that joins epithelial cells & acts as a barrier to the diffusion of substances
Junctional Complex
Long, immotile microvilli
Most found in organ of corti
stereocilia
Domain with special Structural Surface Modifications
Apical Domain
White Adipose Tissue
How would you characterize adipose tissue structure?
Isolated adipocytes are spherical but appear polyhedral or oval in the tissue
Functions of white adipose tissue
Storage of excess carbohydrates and triglycerides
Insulation
Cushioning of internal organs
Synthesis and production of leptin
What does adipose tissue originate from and how does it develop?
Derived from mesoderm mesenchyme

Mesenchymal cells differentiate into lipoblasts and form lipid droplets in cytoplasm
What regulates white adipose tissue?
Leptin gene controls amount of leptin produced by mature adipocytes
What is metabolism in terms of adipose tissue regulation?
Break down of triglycerides so they can be transported in the bloodstream
What is disposition in terms of adipose tissue regulation?
Uptake of glycerol and fatty acids to form triglycerides for storage
What protein causes the brown adipose tissue to be brown?
Cytochrome oxidase from mitochondria
What is the function of brown adipose tissue?
Thermogenesis,
Where in adults is brown adipose tissue found?
Adrenal glands
Aorta
Neck
Explain the pathophysiology of cellulite
Adipose cell chambers swollen --> Restriction of circulation --> Reduces oxygen supply --> decreased metabolism --> trapped water and solutes as a result of softer connective tissue bands --> pinching tiny nerve fibers --> pain
What is hyaline cartilage made up of?
Type II cartilage fibers, proteoglycans, hyaluronic acid
What is elastic cartilage made up of?
Type II cartilage fibers, proteoglycans, hyaluronic acid, elastic fibers, and elastic lamellae
What is fibrocartilage made up of?
Type I & II cartilage fibers, proteoglycans, and hyaluronic acid
What does the matrix of hyaline cartilage consist of?
Collagen, proteoglycans, glycoproteins, and noncollagenous proteins

Contains chondrocytes
Function of hyaline cartilage
Reducing friction
Lubricating joints
Distributing forces applied to bone
Type II collagen
Forms the bulk of the fibril
Type X collagen
organized collagen fibrils into 3-D Lattice
Type IX collagen
facilitates fibril size and interacts with the matrix proteoglycans
Type XI collagen
Regulates fibril size
Type V collagen
Located in the periphery of the chondrocyte, it attaches the collagen types to the framework
3 glycosaminoglycans present in proteoglycans
Hyaluronic acid, chondroitin sulfate, keratan sulfate
Noncollagenous proteins
Regulatory and structural proteins that influence the interactions between chondrocytes and the matrix
Hyaline cartilage
isogenous groups
interterritorial matrix
Elastic Cartilage
Dense connective tissue that surrounds most hyaline cartilage
Perichondrium
Where is hyaline cartilage present?
Trachea, larynx, bronchi, nose, e
Where is elastic cartilage present?
External ears, walls of external acoustic meatus, Eustachian tube, epiglottis
Appositional growth for cartilage
Forms new cartilage at the surface of existing cartilage (near perichondrium) via chondroblasts.
Interstitial growth for cartilage
Division of chondrocytes within lacunae
Why can't cartilage heal itself when it is damaged?
No blood vessels, No mobility for chondrocytes, and limited proliferativity for mature chondrocytes
Pathophys of Osteoarthritis
Thinning of cartilage --> bones rub together --> loss of movement of joints

aging, obese, previous injured patients effected
DDH - developmental dysplasia of the hip pathophysiology
Hip joint not formed properly

Allows femoral head to slip in & out of pocket
Chondrosarcoma
pleomorphic condrocytes piled together in a haphazard arrangement
Chondrosarcoma
Loose connective tissue
Simple Columnar
Dense connective tissue (Collagen)
Cardiac muscle tissue
Nervous tissue
Bone
Red Bone Marrow
Yellow Bone Marrow
What does yellow bone marrow contain?
Fat, connective tissue, some white blood cells
What occurs during endochronal ossification
Perichondrial cells --> osteoblasts (periosteum cells)

Bone cuff is formed

Chondrocytes become hypertrophic and cease production of collagen and secrete alkaline phosphatase (for mineral deposition)

Matrix is calcified.

Periosteal bud invades cavity left by chondrocytes

Blood vessels invade proximal epiphyseal cartilage
perimysium
Smooth muscle tissue
Blood vessel
Muscle fiber attacked by lymphocytes
Necrotic cardiac tissue with a hemorrhage in the interstitum
these cells are derived from mesenchymal stem cells and give rise to osteoblasts.
Osteoprogenitor cells
secrete extracellular matrix and are responsible for new bone formation. Once the osteoblast is finished filling in a cavity the cell becomes flattened and line the surface of the cell. They are now called lining cells
Osteoblasts
bone-resorbing cells that are responsible for “dissolving” the bone when the bone is being removed, reorganized, or where the bone is damaged. These cells are the result of more than one cell fusing, and therefore, usually have more than one nucleus
Osteoclasts
these cells are derived from osteoblasts. When new bone is being formed some of the osteoblasts are surrounded with its secreted matrix and form osteocytes. These cells develop long branches in order to avoid isolation.
Osteocytes