Histology - Renal And Respiratory Clinical Lectures

Front 1

Glomerular Injury

Back 1

Will have hypercellularity due to increased leukocytes due to inflammation.
Will have thickening of the BM, due to hyalnosis, which is deposit of hyaline, distance of filtration to occur becomes increased.
Sclerosis - fibrotic tissue deposits

Front 2

Acute Proliferative (Poststreptoccocal Post infectious) GN

Back 2

Inflammatory reaction to infection or injury at capillary wall. Inflammation of the wall, with deposits in the membrane, this would permit escape of blood, proteins from capillary to urinary space.
Will cause nephritic syndrome.

Front 3

Nephrotic Syndrome

Back 3

Hematuria- blood in the urine
Oliguria - small volumes of volume being produced
Hypertension - high blood volume
Proteinuria - protein in urine
Edema

Front 4

Characteristics of what can pass through basement membrane in nephron

Back 4

1) Size - large particles cannot pass
2) Charge - heparin sulfate (is negative), other negatively charged particles cannot pass
3) Shape

Front 5

Antigen-Antibody Deposits

Back 5

Occur from poststreptococcal infection. Deposits can occur either under your endothelial cells (subendothelial deposits), within the basement membrane (membranous - linear (rest granular), the mesangium (mesangial cells) or under the podocytes (sub epithelial deposits)

Front 6

Inflammation of Glomerulus

Back 6

Renal corpuscle with edema and increased in cellularity due to inflammation.