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138 Cards in this Set

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What are the 3 tissue types of Muscle Tissue?
•Skeletal Muscle
•Cardiac Muscle
•Smooth Muscle
Skeletal Muscle
Attached to skeletal system (bone)
Functions of Skeletal System:
•Maintain body temperature
•Stores nutrient reserves
•Protection
Skeletal Muscle Structures are ?
•Muscle Tissue
•Connective Tissue
•Nerves
•Blood Vessels
Muscle Tissue is also referred to as?
Muscle Cells or Muscle Fibers
3 layers of the connective tissue in the skeletal system are:
•Epimysium
•Perimysium
•Endomysium
Epimysium
Exterior collagen later that separates muscle from surrounding tissues
Perimysium
Surrounds muscle fiber bundles
(Fascicles)
Endomysium
Surrounds individual muscle cells
(Muscle Fibers)
When does Endomysium, Perimysium, and Epimysium come together ?
At ends of muscles to form connective tissue attachment to bone matrix
-Tendon (bundle)
-Aponeurosis (sheet)
Muscle Fascicle
Bundle of muscle fibers (muscle cells)
Sarcolemma
Cell membrane of muscle fiber
Sarcoplasm
Cytoplasm of muscle fiber
Skeletal Muscle Fiber
Skeleton muscle cell
Transverse Tubules (T-tubules)
•Filled with extracellular fluid
•Transmit action potential through the cell
Myofibrils
Encircled with T-tubules & Compose the bundles of protein filaments (myofilaments)
Sarcoplasmic Reticulum
Surrounds each myofobril, and is similar to Smooth Er
What does Sarcoplasmic Reticulum form?
Terminal Cisternae
Triad
Formed by 1 T-tubule and 2 terminal cisternae
What are Myofilaments responsible for?
Muscle Contraction
Thin Filaments
Actin
Thick Filaments
Myosin
Sarcomeres
The repeating functional units myofilaments are organized into
Sarcomere Organization:
•Think/Thin Filament
•Stabilizing proteins
•Proteins that regulate the interaction between thick and thin filament
There are 4
A band
The length of thick filament
dArk band
M line
Center of a band; midline
H zone
In a resting muscle contains no thin filaments
Zone of overlap
Thin & thick filaments
I band
Contains only thin filament
light band
Z lines
The centers of the "I" bands
Titin
Strands of proteins
Muscle Striations
A striped or striated pattern within myofibrils
Muscular Dystrophy
Condition that causes progressive muscular weakness and deterioration
Fiche be Muscular Dystrophy
Muscles damage repeated contract and relax with use; Muscle fibers weaken and die
What are the 4 types of thin filament proteins?
•F-actin (filamentous actin)
•Nebulin
•Tropomyosin
•Troponin
Filamentous Actin
Two rows of twisted globular G-actin that contains active sites that bind to myosin (thick filament)
Nebulin
Holds F-actin together
Tropomyosin
Double stranded protein, that cover the active sites and prevents actin-myosin interaction
Troponin contains 3 globular subunits, which are?
•1 binds to Tropomyosin
•1 binds to G-actin
•1 binds to Ca+2
Myosin
Interacts with actin filaments, forming cross-bridges
Axon Terminal
Contains vesicles filled with acetylcholine (ACh)
Neurotra
Chemical released by a neuron to change the membrane properties of another cell
Synaptic Cleft
Narrow space separates the axonterminal of the neuron from sarcolemma
Junctional folds
Increased surface area
Motor End Plate contains:
•Juntional Folds
•ACh receptors
There are 2
Acetylcholinesterase AChE
Enzyme breaks down AChE, within synaptic cleft
Steps of the Contraction Cycle:
1) Exposure of active sites
2) Attachment of cross-bridges
3) Power stroke
4) Detachment of the cross-bridges
5) Recovery stroke
There are 5
Rigor Mortis
Body becomes stiff, no circulation or oxygen to the muscles
Death || Oxygen is needed for ATP
The all-or-none principle
A muscle fiber is either contracted or relaxed
Tension of a single muscle fiber depends on?
•The # of pivoting cross-bridges
•The fiber's resting length at the time of stimulation
•The frequency of stimulation
There are 3
Tension of a single Muscle Fiber - Length ?
Tension relationship
Number of pivoting cross-bridges depends on:
Amount of overlap between thick and thin fibers
Optimum overlap produced greatest amount of tension:
The maximum number of cross-bridges can form
Highest tension
Twitch
Single stimulus-concentration-relaxation sequence in a muscular fiber
3 phases of twitching are?
•Latent Period
•Contraction Phase
•Relaxation
Latent Period
Before concentration, & Ca+2 is released (Lag Phase)
Concentration Phase
Calcium ions binds, tension builds to peak
Relaxation
Ca+2 levels fall, active sites are covered and tension falls to a resting
Wave Summation
Repeated stimulation's before the end of relaxation phase that causes increasing tension
Incomplete Tetanus
Stimulation continues and the muscle is never allowed to relax completely
Complete Tetanus
Increasing stimulation rate until the relaxation phase is eliminated. Ca+2 cannot be reclaimed
Treppe
Repeated stimulation immediately after relaxation phase that causes a series of concentration with increasing tension
Stair-Step
2 types of skeletal muscle tension:
-Isotonic Contraction
-Isometric Cntraction
Isotonic Contraction
Contraction in movement takes place
2 types of Isotonic Contraction:
•Concentric Contractions
•Eccentric Contractions
Concentric Contractions
Muscle decreases in length against an opposing load
Eccentric Contractions
The muscle increases in length as it resist a load
Isometric Contraction
Contraction in which no movement takes place
Creatine Phosphate (CP)
The storage molecule for excess ATP energy and resting molecule
ATP can be produced by ?
•Aerobic Metabolism
•Anaerobic Glycolysis
There are 2 ways
Aerobic Metabolism
Fatty acids in the mitochondria
Anaerobic Glycolysis
In the cytoplasm
What type of connective tissue surrounds individual muscle fibers?
Endomysium
What type of connective tissue surrounds individual muscle fibers?
Endomysium
What is the plasma membrane of a muscle fiber called ?
Sarcolemma
What type of connective tissue surrounds individual muscle fibers?
Endomysium
What is the plasma membrane of a muscle fiber called ?
Sarcolemma
The thin myofilament is also known as the _______ myofilament.
Actin
What type of connective tissue surrounds individual muscle fibers?
Endomysium
What is the plasma membrane of a muscle fiber called ?
Sarcolemma
The thin myofilament is also known as the _______ myofilament.
Actin
Which molecule covers the active site on actin?
Troponin
What type of connective tissue surrounds individual muscle fibers?
Endomysium
What is the plasma membrane of a muscle fiber called ?
Sarcolemma
The thin myofilament is also known as the _______ myofilament.
Actin
Which molecule covers the active site on actin?
Troponin
The A band is made up of
Actin and myosin
What type of connective tissue surrounds individual muscle fibers?
Endomysium
What is the plasma membrane of a muscle fiber called ?
Sarcolemma
The thin myofilament is also known as the _______ myofilament.
Actin
Which molecule covers the active site on actin?
Troponin
The A band is made up of
Actin and myosin
The structural and fictional unit of skeletal muscle is the ...
Sarcomere
What type of connective tissue surrounds individual muscle fibers?
Endomysium
What is the plasma membrane of a muscle fiber called ?
Sarcolemma
The thin myofilament is also known as the _______ myofilament.
Actin
Which molecule covers the active site on actin?
Troponin
The A band is made up of
Actin and myosin
The structural and fictional unit of skeletal muscle is the ...
Sarcomere
The special movement of the thumb that enables it to grasp and hold an object is:
Opposition
What type of connective tissue surrounds individual muscle fibers?
Endomysium
What is the plasma membrane of a muscle fiber called ?
Sarcolemma
The thin myofilament is also known as the _______ myofilament.
Actin
Which molecule covers the active site on actin?
Troponin
The A band is made up of
Actin and myosin
The structural and fictional unit of skeletal muscle is the ...
Sarcomere
The special movement of the thumb that enables it to grasp and hold an object is:
Opposition
Which functional joint is freely movable?
Diarthrosis
What type of connective tissue surrounds individual muscle fibers?
Endomysium
What is the plasma membrane of a muscle fiber called ?
Sarcolemma
The thin myofilament is also known as the _______ myofilament.
Actin
Which molecule covers the active site on actin?
Troponin
The A band is made up of
Actin and myosin
The structural and fictional unit of skeletal muscle is the ...
Sarcomere
The special movement of the thumb that enables it to grasp and hold an object is:
Opposition
Which functional joint is freely movable?
Diarthrosis
What structures are found in the knee joint that help absorb shock in the joint?
Menisci
What type of connective tissue surrounds individual muscle fibers?
Endomysium
What is the plasma membrane of a muscle fiber called ?
Sarcolemma
The thin myofilament is also known as the _______ myofilament.
Actin
Which molecule covers the active site on actin?
Troponin
The A band is made up of
Actin and myosin
The structural and fictional unit of skeletal muscle is the ...
Sarcomere
The special movement of the thumb that enables it to grasp and hold an object is:
Opposition
Which functional joint is freely movable?
Diarthrosis
What structures are found in the knee joint that help absorb shock in the joint?
Menisci
Type of movement that results when the forearm rotates so that the palm faces anteriorly
Supination
What type of connective tissue surrounds individual muscle fibers?
Endomysium
Which type of joint is found between the root of a tooth and the mandible/maxillae
Gomphosis
What is the plasma membrane of a muscle fiber called ?
Sarcolemma
The thin myofilament is also known as the _______ myofilament.
Actin
Which molecule covers the active site on actin?
Troponin
The A band is made up of
Actin and myosin
The structural and fictional unit of skeletal muscle is the ...
Sarcomere
The special movement of the thumb that enables it to grasp and hold an object is:
Opposition
Which functional joint is freely movable?
Diarthrosis
What structures are found in the knee joint that help absorb shock in the joint?
Menisci
Type of movement that results when the forearm rotates so that the palm faces anteriorly
Supination