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12 Cards in this Set

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What is a PHENOTYPE determined by?

The proteins that are produced as a result of GENE EXPRESSION.

What do INTRA and EXTRA cellular factors control?

They control what genes are expressed by controlling transcription and translation

What is RNA?

It's like DNA but...


-RNA is single stranded


-URACIL replaces THYMINE


- Has RIBOSE sugar instead of DEOXYRIBOSE sugar

What is mRNA?

-mRNA is MESSENGER RNA


-It carries a copy of the Dna code from the nucleus to the ribosome with each triplet of bases called a codon.

What are ribosomes made of?

rRNA and proteins

Describe TRANSCRIPTION

Transcription is the first part of the process of making a protein. It takes place inside the cell nucleus. Transcription involves copying the DNA and the stages are:

1. The DNA in a gene unzips so that both strands are separate – one strand is used as a template


2. Complementary bases attach to the strand being copied – C joins to G and so on


3. Thymine (Base T) is not present and a different base, U, joins with A in the way that T would have done


4. This forms a strand of messenger RNA (mRNA)Messenger RNA is small enough to move out of the nucleus and so it travels to the ribosomes in the cytoplasm.

The removal of INTRONS...

The coding regions of a gene are called exons and the intervening non-coding regions are called introns.

When these genes are to be expressed by a cell they need to be copied and the non-coding parts edited out before they can be turned into protein. This process is called RNA splicing.

What are EXONS?

Exons are coding regions which are joined together to form a mature transcript by the process of RNA Splicing.

TRANSLATION is...

The formation of a polypeptide from mRNA at a ribosome.

tRNA

- tRNA has a cloverleaf shape.

- It is made from a single strand of RNA which folds due to base pairing to form this unusual shape.


- It has a triplet anti-codon site and an attachment site for a specific amino acid.

Start and Stop codons

- Start and Stop Codons. The start codon marks the site at which translation into protein sequence begins

- The stop codon marks the site at which translation ends.

How are polypeptides formed?

AMINO ACIDS are joined by PEPTIDE BONDS to form a POLYPEPTIDE which exits the RIBOSOME