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14 Cards in this Set

  • Front
  • Back

What year did the Hepatitis A Vaccine become licensed

1995

Why are raw shellfish a frequent source of infection of Hepatitis A

it's a fecal/oral transmitted disease and raw shellfish can concentrate the virus in their tissues if they come from fecally contaminated waters

Can HepA be sexually transmitted?

yes

What is the incubation period for HAV

30 days

Is there an antivirus for HAV?

No

Explain HAV immunization

passive immunization gives short-term protection against the disease if administered within two weeks of exposure (immune globulin by injection after exposure)




An effective vaccine composed of inactivated HAV has been available since 1995




CDC recommends vaccination of children at 1 yo and high risk groups

explain inactivated vaccines

killed microorganisms or inactivated viruses. made by treating the pathogen with formalin or another chemical that does not significantly change the surface epitopes


The virus can not reproduce yet the body can still create antibodies to it

what kind of virus is hepatitis A?

naked

single stranded RNA


plus strand


picornavirus family



Transmission of HBV

contact with bodily fluids

What are the signs and symptoms of HAV

Acute illness


jaundice


fever


fatigue


clay colored feces


vomiting


after a period of 30 days

What are the signs and symptoms of HBV

acute


asymptomatic to sever



what is the incubation period of HBV

from 2-5 months


acute version is rarely fatal, clears virus within weeks to months of initial symptoms




chronic version (mostly infants and children)


can develop cirrhosis (scarring of liver)


liver failure


liver cancer


other chronic liver disease




Between 2,000-4,000 die from HBV-related diseases annually

What kind of virus is HBV

enveloped with mostly double stranded DNA genome (a portion is single stranded)


remarkably resistant to environmental conditions


Visions can still be infectious after a week outside the body


member of the hepadnavirous family (liver + DNA)

another name for HBV

Dane particle