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26 Cards in this Set
- Front
- Back
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What is an increase in neutrophils called? What does this suggest? |
Neutrophilia: suggests bacterial infection
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What is an increase in lymphocytes called? What does this suggest?
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Lymphocytosis: suggests viral infection
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What is an increase in eosinophils called? What does this suggest?
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Eosinophilia: suggests allergy or parasitic infection
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What change in WBC count would suggest a bacterial infection?
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Neutrophilia (increased number of neutrophils)
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What change in WBC count would suggest a viral infection?
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Lymphocytosis (increased number of lymphocytes)
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What change in WBC count would suggest a parasitic infection?
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Eosinophilia (increased number of eosinophils)
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What change in WBC count would suggest an allergic reaction?
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Eosinophilia (increased number of eosinophils)
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How do you determine the WBC count?
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Component of CBC, determined by a hematology analyzer through various methods
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What does a WBC differential give you?
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Percentages of each WBC type
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How do you perform a manual WBC differential?
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- Scan slide at 40x
- Tally number of each type of WBC until you reach 100 cells counted - Preferred method is bottom to top, L to R, top to bottom, R to L, etc |
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What is the mnemonic for remembering the relative abundance of WBCs from most to least?
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Never Let Monkeys Eat Bananas:
- Neutrophils (34-71%) - Lymphocytes (19-53%) - Monocytes (5-12%) - Eosinophils (0-7%) - Basophils (0-1%) - Band Neutrophils (0-3%) |
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How would you describe the core biopsy?
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Hypocellular marrow for age
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What are the expected CBC results?
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Cytopenias
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What are the clinical consequences of this marrow abnormality?
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- Shortness of breath
- Infections - Bleeding - Petechiae |
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What are the potential causes of this abnormality?
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- Radiation
- Chemotherapy - Lupus - Malignancy - Viral infection - Immunosuppressant agents or conditions |
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In attempts to treat this bone marrow abnormality, which cell type should be transplanted?
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Progenitor Cells
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How do you describe the core biopsy?
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Hypercellular marrow for age
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How do you describe the aspirate smear?
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Monotonous and without maturation
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What cell type is predominating, immature or mature cells?
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Immature cells
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What are the clinical consequences of this marrow abnormality?
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- Shortness of breath
- Infections - Bleeding - Petechiae |
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What are the expected CBC results?
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- Low WBC Count
- Low Platelet Count - Neutropenia - Low RBC Count - Myeloid Leukemia (high myeloid progenitor cells) |
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What is the predominant cell lineage in this aspirate smear?
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Erythroid
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What is the myeloid/erythroid (M/E) ratio compared to a normal M/E (1.5-4)?
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Lower than normal because more Erythroid cells
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What are the expected CBC results?
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Elevated MCV d/t increased reticulocytes
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What growth factor would cause this marrow finding?
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Erythropoietin
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What clinical scenarios may produce this marrow finding?
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- High altitude
- Anemia - Hemorrhage |
