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6 Cards in this Set

  • Front
  • Back
What causes heart failure?
IHD
Cardiomyopathy
Hypertension
Valve disease
Congenital heart disease
Alcohol and drugs
Hyperdynamic circulation
Arrhythmias
Pericardial disease
Infections
What are the features of heart failure?
Ventricular dilatation
Myocyte hypertrophy or apoptosis
Increased collagen synthesis
Altered myosin gene expression
Altered sarcoplasmic Ca ATPase density
Increased ANP secretion
Salt and water retention
Sympathetic stimulation
Peripheral vasoconstriction
Venous return decreased
What are the symptoms of heart failure?
Exertional dyspnoea
Orthopnoea
Paroxysmal nocturnal dyspnoea
Fatigue
What are the signs of heart failure?
Cardiomegaly
HS3
HS4
Elevated JVP
Tachycardia
Hypertension
Bi-basal crackles
Pleural effusion
Ankle Oedema
Ascites
Tender hepatomegaly
What investigations are carried out for heart failure?
Bloods - FBC, LFTS, U and Es, troponins, TFTs
CXR
ECG
ECHO
Nuclear cardiology
Cardiac MRI
Cardiac catheterisation
Cardiac biopsy
Cardiopulmonary exercise testing
24 hour ECG monitoring
What is the treatment of heart failure?
Aim to reduce symptoms and improve QOL
Lifestyle changes - exercise, weight loss, reduce salt and alcohol, stop smoking
Monitoring
Diuretics - beta-blockers, ACE inhibitors, Angiotension II receptor agonist, aldossterone agonist
Cardiac glycosides - digoxin
Vasodilator and nitrates
Transplant, pacemaker or revascularsation