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31 Cards in this Set
- Front
- Back
What are the 2 common phenotypes of Staphylococci?
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1.coagulase +
2. thermostable nuclease + (Staphylococcus Aureues) But not reliable, look for ENTEROTOXIN |
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Ingestion of Staphylococcal enterotoxin are intoxication or infection?
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intoxication >20ng
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How many enterotoxins are identified?
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13
A.B.C1.C.2.C3.D.E.G.H.I.J.K.L. NO F |
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Mode of action of Staphylococcal enterotoxin
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1. act as superantigen that mediates cross linkage between T cells receptor (CD4 T cells) and class II MHC (APC)
2.cross linkage stimulates massive inflammatory responses and releases cytokines such as IL2 |
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Staphylococcal enterotoxin are made out of heat resistant protein.....
Which heat resistrance come first |
SEC>SEB>SEA
CBA |
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Treament: Drink a lot of water to maitin fluid balance,rest
Which bacteria it refer to? |
Staphylococcal enterotoxin
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Gram + , spore forming and aerobic rods is which Bacteria
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Bacillus cereus
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What are the 2 type of illness for Bacillus cereus gastroenteritis?
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Diarrheal
and emetic |
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Emetic syndrome is similar to which type of bacteria ?
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Staphylococcal food poisoning
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Diarrhea syndrome is similar to which type of bacteria
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C. perfringens food poisoning
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what is the key virulence factor for Bacillus cereus enterotoxins?
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Hemolysin BL (HBL)
Hbl shows hemolysis, cytolysis, dermonecrosis, vascular permeability enterotoxic activity |
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What kind of toxin is called cereulide,
short peptide with ring structure, heat stable, cause vomiting, RICE |
EMETIC TOXIN
Bacillus cereus |
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What type of bacteria are gram positive ,spore forming and anaerobic rods
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Clostridium Perfringer
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What type of bacteria is highly fermentative and produce gases
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Clostridium Perfringer
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Which bacteria are classified into 5 groups based on toxins produced
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Clostridium Perfringer
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Describe Clostridium Perfringens enterotoxin (CPE) with 4 details
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1.key virulence factor of type A
2.Synthesized during sporulation 3.Heat sensitive 4.Resistant to trypsin and chymotrypsin |
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Mode of action of Clostridium Perfringer enterotoxin (CPE)
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Bind to host receptor---> form large complex--->change membrane permeability---->death of host cells.
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Which bacteria cell are sensitive to pH and are easily killed by the acidity in stomach
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Clostridium Perfringer
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Which bacteria is among the 3rd 4th foodborne disease in US
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Clostridium Perfringer
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All c.botulinum stairs produce........ which cause botulism
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botulinum neurotoxin
C.botulinum |
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Bacteria are classified based on their .......... and ............?
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1.Toxin type
2. Physiological characteristic C.botulinum |
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C.botulinum neurotoxin is the most toxic natural subtance know. It is also an ..... toxin?
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A-B toxin
a:activity domain(light chain) b. binding domain ( heavy chain) |
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which type of botulism in intoxication?
only 1 |
Food borne botulism
-consumption of toxin pre - formed in food |
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Which 3 types to botulism is infection?
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1.Infant botulism-growth of c.botu in GI
2.adult botulism-growth and production of toxin in adult intestine 3.wound botulism- grow and produce toxin in would like tetanus |
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Which bacteria are the most resistant spores?
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C.botulinum
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which type of bacteris is gram positive and non spore forming rods??
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Listeria monocytogenes
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which bacteria cause the most number of recalls and hospitalization?
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Listeria monocytogenes
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Listeria monocytogenes are monitored by which 2 agency
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Foodnet and pulse net
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which bacteria attack immuno suppressed individuals, newborn and pregnant
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Listeria monocytogenes
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What are the 3 virulence factors for Listeria monocytogenes
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1. internalin - binding and internalization
2.listeriolysin- has beta hemolytic activity and is a cytotoxin 3.ActA triggers host actin polymerization |
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HowListeria monocytogenes spreads from cell to cell
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1.L. mon triggers actin rearrangement in host cell
2. form a tail of actin polymers 3.The actin tails push the bacterial cells through host cells |