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23 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Hexokinase
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Glucose to Glucose 6 Phosphate
Consumes Energy |
Irreversible
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Phosphoglucose Isomerase
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Glucose-6-Phoshate to Fructose-6-phosphate
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Reversible
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6-phosphofructo-1-kinase
Phosphofructokinase(PFK) |
Fructose-6-phosphate to fructose 1-6 biphosphate
Consumes Energy |
Irreversible
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Fructose-biphosphate Aldolase
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Fructose 1-6 Biphosphate to
Dihydroxyacetone Phospate(DHAP) or Glyceraldehyde 3-phosphate(GAP) |
Reversible
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Triose Phosphate Isomerase
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DHAP to GAP
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Reversible
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GAP dehydrogenase
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GAP to 1,3 Biphosphoglycerate
produces NADH |
Reversible
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Phosphoglycerate Kinase
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1-3 Biphosphoglycerate to 3-phosphoglycerate(3-PGA)
Produces ATP |
REversible
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Phosphoglycerate Mutase
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3-PGA to 2-PGA
|
Reversible
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enolase
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2-PGA to Phosphoenolpyruvate(PEP)
Releases water |
reversible
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Pyruvate Kinase
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PEP to pyruvate
produces ATP |
Irreversible
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Lactate Dehydrogenase
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Pyruvate to L-Lactate
Produces NAD+ |
Reversible
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3 Places Glycolysis is Regulated
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Hexokinase, PFK, Pyruvate Kinase
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Hexokinase regulated by
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Allosteric Inhibition by Glucose-6-Phosphate
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PFK Regulated by
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Allosteric Activation: AMP, ADP, Pi, fructose-6-phosphate
Allosteric Inhibition: ATP, Citrate, Fatty Acids |
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Pyruvate Kinase regulated by
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Allosteric Activation:Fructose 1-6 Biphosphate
Allosteric Inhibition: ATP, alanine |
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Fructokinase
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Fructose to Fructose-1-phosphate
consumes energy |
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Fructose-1-Phosphate Aldolase
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Fructose-1-Phosphate to DHAP and GAP
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Galactokinase
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Galactose to Galactose-1-Phosphate
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Galactose-1-phosphate uridyl transferase
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Galactose-1-phosphate to UDP-Galactose, glucose-1-phosphate
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UDP Galactose 4-Epimerase
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UDP-Galactose to UDP-glucose
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Phosphoglucomutase
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Glucose-1-phosphate to Glucose-6-phosphate
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Deficiency of Pyruvate Kinase causes
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hemolytic anemia
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Deficiency of PFK causes
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hemolysis and myopathy
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