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10 Cards in this Set
- Front
- Back
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Glyceryl trinitrate |
· Vasodilator · Decreases preload by increasing venous capacity, pooling venous blood in the peripheral veins, reducing ventricular filling pressure and decreasing arterial blood pressure (after load) · Causes vasodilation in coronary arteries that are in spasms and may assist the redistribution of blood flow along the collateral channels in the heart |
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Metabolism |
Absorbed and metabolised by the liver |
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Indications |
· Suspected ACS (with pain) · Acute cardiogenic pulmonary oedema · Autonomic dysreflexia (with SBP > 160mmHg) · Irukandji syndrome (with SBP > 160mmHg) |
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Contraindications |
· KSAR or hypersensitivity · HR < 50 or > 150 · BP < 100mmHg · Acute CVA · Head trauma · Phosphodiesterase inhibitor medication administration (e.g. viagra or levitra) in the previous 24 hours |
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Precautions |
· Suspected inferior AMI · Cerebral vascular disease · Risk of hypotension and/or syncope · Intoxication (GTN effects are enhanced) · Phosphodiesterase inhibitor medications administration in previous 4 days |
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Side effects |
· Dizziness · Hypotension · Syncope · Reflex tachycardia · Vascular headaches |
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Presentation |
· Spray (sublingual), 400mcg/dose, 200 doses · Ampoule, 50mg/10mL |
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Onset |
< 2 minutes |
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Duration |
20 - 30 minutes |
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Dosage |
SUBLING - 400mcg, repeated at 5 minutes, no max dose |
