Giwk4- 3-23 Path- Coloncancer

Front 1

adenoma type with nucleoli plus branching, L shaped dilated glands, mutated BRAF, dysplasia

large firm polyps with trunk, freckles on lips, palms, genitals

Back 1

sessile serrated adenoma

Peutz-Jegher's hamartomas

Front 2

benign but dysplastic cells- arranged as crypts:

arranged as villi:

shape of nuclei?

where are they most common?

Back 2

tubular adenoma

villous adenoma

cigar-shaped

rectosigmoid area

Front 3

Defect in the APC locus, thousands of tubular/villous adenomas develop in colon:

Polyposis coli with minor birth defects also:

Colon polyps and brain tumors:

Back 3

Familial polyposis coli syndrome

Gardner's syndrome

Turcot's syndrome

Front 4

Colon cancer is usually what type of cancer?

Tumors in the cecum are likely to produce ______________.

Eruption of multiple seborrheic keratoses is the "_________" sign and warns of a ____________ cancer.

Back 4

adenocarcinoma

iron deficiency anemia

Leser-Trelat
occult blood

Front 5

Lakes of mucin containing signet ring cells:

Back 5

mucinous carcinoma

Front 6

Scarring of the liver, disrupts the liver's vascular architecture, fibrous bands dividing liver into nodules:

single-cell apoptosis of a hepatocyte, attacked by T-cell

Back 6

cirrhosis

councilman body

Front 7

distinctive hepatocytes seen in chronic Hep B infection:

hemolysis, elevated liver enzymes, low platelets, serious complication of pregnancy:

Back 7

ground glass hepatocytes

HELLP syndrome

Front 8

rope-like masses of altered cytokeratin and cell stress proteins (ubiquitin, etc)

Gilbert's and Crigler-Najjar result from a mutation in which gene?

Back 8

Mallory's hyaline

glucuronyl transferase

Front 9

Why does a liver patient develop ascites?

What is the first clotting factor to go?

cirrhosis with nodules smaller than 0.3 cm, fibrous-scar bands thin:

Back 9

increased serum albumin

VII

micronodular

Front 10

Micronodular cirrhosis affects the liver evenly or unevenly?

One common cause?

Nodules >0.3 cm, fibrous bands thin:

common causes?

Back 10

evenly

alcoholism

macronodular

Wilson's disease, galactosemia, a-1-antitrypsin deficiency

Front 11

Eponym for hepatic vein thrombosis?

most common causes?

Councilman bodies are common with what disease?

Back 11

Budd-Chiari

polycythemia vera, hypercoagulable state, hepatic carcinoma

Viral hepatitis

Front 12

transmitted fecal-oral, poor sanitation, endemic on Indian reservations:

world's most serious DNA-virus related problem, 300 million carriers, ROI transfusion, shared needles:

Back 12

Hep A

Hep B

Front 13

autoimmune disease caused by Ab's against pyruvate dehydrogenase:

A common drug especially hard on the liver:

"The death angel" mushroom:

Back 13

primary biliary cirrhosis

Acetomeniphen

amanita phalloides

Front 14

suppuration involving the bile ducts, underlying cause is almost always obstruction, neutrophils in bile ducts:

"anchovy paste" necrosis without inflammation, hyatid cysts:

Back 14

bacterial cholangitis

amebid abscesses

Front 15

Fatty change to the Ito cells, stellate cell lipidosis:

giant mitochondria in alcoholic hepatitis:

increased total body iron from any cause:

Back 15

Vitamin A overdose

Yokoo bodies

hemosideriosis

Front 16

hemosideriosis that damages liver parenchyma:

Classic triad of hemochromatosis:

autosomal-recessive problem, too much copper in blood:

Back 16

hemochromatosis

liver trouble, DM, skin color change

Wilson's disease