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10 Cards in this Set
- Front
- Back
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Presentation of esophageal CA
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almost always dysphagia
sometimes weight loss less common->CP, GI bleeding, SOB occasionally w/ distant metastatic dz (no serosa) |
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Which CA is rapidly increasing?
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adenoCa rapidly inc, SCCa stagnant
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Mean age of onset of esophageal CA
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app. 70 yr
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SCCa risk factors
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AA
lower SES smoking, EtOH, toxic ingestion |
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AdenoCA risk factors
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more common in whites
assoc w/ reflux & development of Barrett's esophagus |
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DDx with esophageal CA
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esophageal strictures
extrinsic compression of esophagus (other CA, aneurysms) viral infection of esophagus benign esophageal growths erosive esophagitis |
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Testing for esophageal CA
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endoscopy
(can have barium esophagram) Endoscopic ultrasound (EUS), CT or MRI |
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Best therapy for esophageal cancer
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resection (high morbidity, 2-18% mortality)
Rads/chemo usually palliative or pre-op to shrink stents inside esophagus |
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1 yr & 5 yr survival rates
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1 yr= 18%
5 yr= 10% even those resectable are <50% for 5 yr |
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Where do benign esophageal tumors tend to grow?
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submucosally
(as opposed to more surface w/ malignant) |
