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10 Cards in this Set
- Front
- Back
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What three things stimulate parietal cells?
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Gastrin, histamine, and ACh
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What occurs due to stomach distention?
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ACh is released to stimulate parietal cells directly, histamine is released to stimulate parietal cells, and GRP goes to the G cells to cause gastrin release
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True/False: The same things that stimulate secretion in the parietal cell stimulate the chief cells
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TRUE--gastrin, ACh, and histamine
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What do protein breakdown products in the stomach stimulate?
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Gastrin release from G cells and histamine release
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Fats stimulate the _____ in the duodenum and acid stimulates the _____ in the duodenum.
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Fats stimulate the I cells to release CCK and acid stimulates S cells to release secretin
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Classic gallstone pain is when?
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DURING a meal--contraction of gallbladder against that stone causes pain
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What happens when basal acid levels in the stomach drop below pH 3?
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This stimulates D cells to produce somatostatin inhibiting G cells from producing gastrin and also stimulates secretin to be released to control the low pH
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Stretch at the ileocecal valve induces what two reactions?
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Positive stimulation at the valve to contract and negative repression at in the ileum to suppress continued movements
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Stretch at the rectum induces what?
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Repression of inner sphincter contraction and induction of colon contractions to move the food along
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How do proton inhibitors work?
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By blocking the H/K ATPase--it doesn't matter what stimulates the parietal cell it won't be able to secrete-->you have to create new epithelial cells(turnover) to make more acid
The only cells that are blocked are the ones with active pumps and so you don't lose acid secretion all together |
