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26 Cards in this Set
- Front
- Back
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risk factors in pancreatic
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cigarette smoking
diet obesity diabetes occupational familial ***NOT AGE |
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tumor marker for pancreatic
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CA 19-9, not specific for pancreatic
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Whipple procedure (pancreaticduodenectomy) can be performed when tumor
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is in head of pancreas
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surgery + radiation in pancreatic
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rad post-surgery. Rad alone doesn't improve survival
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neoadjuvant 5FU + rad
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improves resectability rate but not survival
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intraoperative radiotherapy w/pancreatic
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no survival benefit
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most successful agents in pancreatic
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5FU + gemcitabine
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patients who have resectable pancreatic cancer should receive
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postoperative chemoradiation (w/5FU) + gemcitabine or chemotherapy alone
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patients with unresectable (locally advanced) pancreatic cancer
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no evidence that gemcitabine is better than 5FU tx
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fixed dose rate for gemcitabine infusion
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10mg/m2/min
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reason for fixed dose rate gemcitabone infusion
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theoretically allows for higher concentration of active form which may = improved cytotoxicity and effectiveness
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Creon-10: what does the 10 refer to?
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dose of lipase (10,000 units)
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dosing pancreatic enzymes
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titratue up if stools greasy, malodorous or float and reduce if constipation
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nutrition supplementation w/ pancreatic end-stage
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parenteral nutrition not indicated. Try enteral feeding or appetite stimulants
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most gastric cancers begin in the...
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mucosa (innermost layer) and invade lymph nodes
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H Pylori in gastric cancer
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increases risk
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type A blood in gastric cancer
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increases risk
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number of lymph nodes that must be sampled to assign N status to gastric tumor
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15
Stage IV has > 15 nodes |
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treatment of choice in gastric
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surgery when it can be palliative or curative
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After curative resection,
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adjuvant rad alone or chemo/rad used. Neoadjuvant rad is not standard
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treatment gastric cancer-
stage I |
surgical resection w/ lymph node disection only for Ia. Observation or 5FU based chemorad or ECF
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treatment gastric cancer-
stage II-III |
surgical resection w/ lymph node disection or pre-op chemo (ECF) or pre-op chemorad then resection. Adjuvant 5FU chemorad recommended if ECF pre-op Observation or 5FU based chemorad or ECF
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treatment gastric cancer-
unresectable |
5FU based chemorad or chemo
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treatment gastric cancer-
stage IV |
palliative chemo
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liver cancer risk factors
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*****Hep B
Hep C cirrhosis anabolic steroids hereditary hemochromatosis |
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standard for HCC
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resectable: surgery
unresectable: sorafenib 400mg PO BID |
