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18 Cards in this Set
- Front
- Back
most common benign liver tumor, is a proliferation of vascular tissue that appears as a spongy mass, but is asymptomatic
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Hemangioma
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this is a benign liver tumor, often seen in young women and is related to the use of oral contraceptive use.
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Hepatic adenoma (liver cell adenoma)
Micro: resembles normal liver except for the lack of portal tracts Subcapsular adenomas may rupture, causing an intraperitoneal hemorrhage |
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this is the most common primary malignant tumor of the liver, is more commonly seen in Asian people. What is it and the likely etiological causes?
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Hepatocellular carcinoma (HCC)
Etiology: cirrhosis, hepatitis B and C virus, alcohol, aflatoxin B1 |
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What is the tumor marker for Hepatocellular carcinoma?
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alpha-fetoprotein (AFP)
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young person with hepatocellular carcinoma shows up with no alcohol use...what do they have?
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Fibrolamellar variant: younger age, fibrous bands, and better prognosis
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world wide, what is the most common cause of hepatocellular carcinoma? US?
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world: Hepatitis
US: booze |
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Thorotrast (contrast media used by radiologists) and clonorchis sinesis (liver fluke) are risk factors for this uncommon malignant liver tumor
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Cholangiocarcinoma
Micro: adenocarcinoma arising from bile duct epithelium |
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this is a rare maligant vascular neoplasm.... what are some of the things that can lead to them?
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Angiosarcoma
Chemical carcinogens: vinyl chloride, thorotrast, and arsenic Aggressive tumors with a poor prognosis |
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Female gender
Obesity Pregnancy Oral contraceptives and hormone replacement therapy (HRT) Incidence increases with age Genetics (Native American Pima and Navajo Indians) are risk factors for what? |
Cholesterol stones (in the gallbladder)
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people with chronic hemolytic anemias, cirrhosis, bacteria, parasites, are more likely to get what kind of gallstones?
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Pigmented bilirubinate stones
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the findings of this tumor would be a greenish yellow hue, with satellite nodules
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Hepatocellular carcinoma (HCC)
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person is colicky, has right upper quadrant tenderness on palpation, nausea and vomiting with low grade fever. What is going on
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Acute cholecystitis
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micro findings of chronic inflammation and Rokitansky-Aschoff sinuses are associated with?
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Chronic cholecystitis
Late complication: calcification of the gallbladder (“porcelain gallbladder”) |
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Gross: yellow speckling of the red-tan mucosa (“strawberry gallbladder”)
Micro: collections of lipid-laden macrophages within the lamina propria |
Cholesterolosis
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chronic obstruction of the cystic duct leads to the resorption of the normal gallbladder contents and enlargement of the gallbladder by the production of large amounts of clear fluid or mucous secretions
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Hydrops of the gallbladder (mucocele)
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what are the symptoms of gallbladder cancer?
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there really aren't any until late in the course
Cholecystitis Enlarged palpable gallbladder Biliary tract obstruction (uncommon) |
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Primary liver cancer...what is it?
cause? *** |
Hepatocellular carcinoma
Asia and Japan > US Etiology: cirrhosis, hepatitis B and C virus, alcohol, aflatoxin B1 |
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common sites for metastatic tumor lesions to travel to? 3
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colon
breast lung Tend to occur as multiple well circumscribed masses |