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18 Cards in this Set

  • Front
  • Back
most common benign liver tumor, is a proliferation of vascular tissue that appears as a spongy mass, but is asymptomatic
Hemangioma
this is a benign liver tumor, often seen in young women and is related to the use of oral contraceptive use.

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Hepatic adenoma (liver cell adenoma)

Micro: resembles normal liver except for the lack of portal tracts

Subcapsular adenomas may rupture, causing an intraperitoneal hemorrhage
this is the most common primary malignant tumor of the liver, is more commonly seen in Asian people. What is it and the likely etiological causes?
Hepatocellular carcinoma (HCC)

Etiology: cirrhosis, hepatitis B and C virus, alcohol, aflatoxin B1
What is the tumor marker for Hepatocellular carcinoma?
alpha-fetoprotein (AFP)
young person with hepatocellular carcinoma shows up with no alcohol use...what do they have?
Fibrolamellar variant: younger age, fibrous bands, and better prognosis
world wide, what is the most common cause of hepatocellular carcinoma? US?
world: Hepatitis

US: booze
Thorotrast (contrast media used by radiologists) and clonorchis sinesis (liver fluke) are risk factors for this uncommon malignant liver tumor
Cholangiocarcinoma

Micro: adenocarcinoma arising from bile duct epithelium
this is a rare maligant vascular neoplasm.... what are some of the things that can lead to them?
Angiosarcoma

Chemical carcinogens: vinyl chloride, thorotrast, and arsenic
Aggressive tumors with a poor prognosis
Female gender
Obesity
Pregnancy
Oral contraceptives and hormone replacement therapy (HRT)
Incidence increases with age
Genetics (Native American Pima and Navajo Indians)

are risk factors for what?
Cholesterol stones (in the gallbladder)
people with chronic hemolytic anemias, cirrhosis, bacteria, parasites, are more likely to get what kind of gallstones?
Pigmented bilirubinate stones
the findings of this tumor would be a greenish yellow hue, with satellite nodules
Hepatocellular carcinoma (HCC)
person is colicky, has right upper quadrant tenderness on palpation, nausea and vomiting with low grade fever. What is going on
Acute cholecystitis
micro findings of chronic inflammation and Rokitansky-Aschoff sinuses are associated with?
Chronic cholecystitis

Late complication: calcification of the gallbladder (“porcelain gallbladder”)
Gross: yellow speckling of the red-tan mucosa (“strawberry gallbladder”)
Micro: collections of lipid-laden macrophages within the lamina propria
Cholesterolosis
chronic obstruction of the cystic duct leads to the resorption of the normal gallbladder contents and enlargement of the gallbladder by the production of large amounts of clear fluid or mucous secretions
Hydrops of the gallbladder (mucocele)
what are the symptoms of gallbladder cancer?
there really aren't any until late in the course

Cholecystitis
Enlarged palpable gallbladder
Biliary tract obstruction (uncommon)
Primary liver cancer...what is it?

cause?

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Hepatocellular carcinoma

Asia and Japan > US
Etiology: cirrhosis, hepatitis B and C virus, alcohol, aflatoxin B1
common sites for metastatic tumor lesions to travel to? 3

**
colon

breast

lung

Tend to occur as multiple well circumscribed masses