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150 Cards in this Set

  • Front
  • Back

changes in appearance from shrinkage noted after

fifth decade

loss of water in intervetrebal discs

lose 1 cm q 10 years after age 40

hyphosis

hunchack

sarcopenia

natural loss of muscle tissue from aging

lower extremity atrophy

earlier than upper, issues with falls

what lines joints

hyaline cartilage

main joint of hyaline wear and tear

knee

amount of collagen does not change but becomes

stiffer

metabolic bone disease

osteoporosis

joint disease

osteoarthritis, rheaumatoid arthritis, gout

OA is

noninflammatory

RA and gout are

inflammatory

noninflammatory distinguished by 3 sns

lack of synovial inflammation, absensce of systemic manifestations, normal synovial fuid

inflammatory distinguished by 3 sns

synovial inflammation, systemic manifestations, abn synovial fluid

most common metabolic disease

osteoporsis

osteoporiss in women

50%

long term coritco does what to bones

weakens

osteoporosis more common in

whites, asians

2 drugs that increase risk of osteoporosis

anticonvulsant, thyroidhormoone

4 modifiable risk factors for osteoporosis

low Ca intake, prolonged immobility, excessive caffeine/alcohol, smoking

osteoporosis primary type 1

bone destroyed more rapidly than made

osteoporosis primary type 1 increased incidence of

vertebral fractures

osteoporosis primary type 1 occurs when

postmenopausal, related to estrogen levels

osteoporosis primary type 2

senescent bone loss

osteoporosis primary type 2 causes decrease in

actual amount of bone formed during remodeling

osteoporosis primary type 2 increased risk of

hip fractures

osteoporosis secondary commonly from (2)

steroids, vit d defecient

osteoporosis sns

usually absent

osteoporosis referred to as

silent killer

first sign of osteoporosis is usually

fractures

loss of height is called

dowager's hump

BMD

bone mineral density

gold standard for measuring bmd

DEXA

DEXA

dual energy xray absorptiometry

DEXA is very

$$$

Calcium slows

the rate that bone is lost

what Ca is better

citrate is better than carbonate

tums is Ca

carbonate

to prevent osteoporosis avoid beverages containing

phosphorous because is inversely r/t Ca

2 things bad for osteoporosis

tobacco smoking, alcohol

high Ca foods (10)

dairy, dried figs, fish c bones, fortified OJ, beans, spinach, turnips greens, chocolate, nuts, liver

3 foods enhancing Ca excretion

caffeine, excess fiber, meat phosphorous

antiresorptive drugs do what

preserve or inc BD and dec rate of bone resorption

3 antiresorptive drugs

bisphophonates, estrogen, calcitonin

estrogen use

is controversial

bisphosphonate main drug

fosamax

bisphosphonate actonel

daily or weekly

bisphosphonate fosamax

daily or weekly

bisphosphonate boniva

monthly

most serious side effects of bisphosphonates

esophagitis

bisphosphonates can also cause

osteonecrosis of jaw

esophagitis

prolonged drug exposure

bisphosphonates - difficulty swallowing

causes heartburn

most important thing about bisphosphonate (bis) therapy

TEACH TEACH TEACH

bis TEACH - to prevent

esophageal irritation

bis TEACH - take atleast 1 hr before

any meds or food

bis TEACH - take with what fluid

water and nothing else

bis TEACH - do what for 30-60 min post drug admin

sit upright

bis TEACH - do not do what for 30 min post admin

drink anything

bis TEACH - do not take what med at same time

Ca

bis TEACH - Ca may interfere with

bis drug absorption

estrogen supp ie

evista

FDA and estrogen supps

no longer approved

estrogen supps for

osteoporosis

estrogen supps inc risk for (5)

breast ca, blood clots, MI, CVA, endometrial ca

estrogen supps now for

short term use for menopause sns

estrogen supps research

still in progress

calcitonin tx for osteoporosis

safe but less effective

>95% of oa hip fractures caused

by falls

leading cause of accidental death in age 65+

falls

intracapsular fx located

within joint

intracapsular fx causes

impaired blood to femoral head

extracapsular fx located

trochanter, below trochanter

extracapsular fx causes

acute blood loss from vascular cancellous bone surfaces

extracapsular fx rarely cause

avascular necrosis

what can cause hip fx

neoplasms

hip fx can cause (3)

sepsis, bleeding, death

death from hip fx - #s

1/5 die within 1 year

leg of hip fx

shortened and externally rotated

most hip fx occur

in women who fall sideways on hip

hip fx Sx

is tx of choice

important post-op care for hip sx

keep extremity aligned

hip fx post-op ambulation

asap

pre and post op pt edu

prevent dislocation, encourage physical therapy, use assistive devices

prevent dislocation how

dont cross legs, use raised toilet, pillow b/t legs

most common form of arthritis in US

osteo

osteoarthritis is leading cause

of disability in ppl over 65

OA joints

hands, knee, hip, central joints of cervical and lumbar

OA characterized by

progressive erosion of articular cartilage with formation of bone in joint space

does OA have exacerbations and remissions

no

OA is asymmectric or symmectric

asymmetric

most signif cause of eldelry pain and disability

OA of hips and knees

OA not caused by

aging alone

OA called the (2)

wear and tear, or a mileage phenomenon

OA predisposing factors (2)

repetitive joint use (running), cold climate

OA predisposing factors (5)

inc age, obestiy, trauma, lifestyle, genetics

2 clinical manifestations of OA in hands

heberden's nodes, bouchard's nodes

OA pain

morning stiffness, usually resolves in 30 min, ? confirm that

OA will have what c movement

crepitus

OA physcial assess look for

erythema

OA heat to joints

dec pain

OA cold to joints

dec swelling

4 major complications of hip/knee replacement

thromboembolsim, infection, blood loss, joint dislocation

CPM device

continuous passive motion device

CPM device for

post knee replacemnet

OA topical analgesics most effective for

hands and knees

OA topical analgesics may cause

heat or burning

OA topical analgesics agent

capsaicin found in keyan pepper

OA systemic analgesics agent

acetaminophen

how much acetaminophen

4g/day

acetaminophen has what effect

ceiling effect

acetaminophen - tylenol

one of safest drugs

most common OA pain tx

NSAIDS

NSAIDS given post

tylenol

NSAIDS long term (4)

ulcers, bleeding, inc MI risk, inc CVA risk

3 NSAIDSie

aspirin, ibuprofen, naproxen

cox 2 inhibitors ie

celebrex

celebrex is anti

inflammatory

celebrex requires

rx

celebrex considered safe for

GI tract

celebrex inc risk for

CV SE

celebrex SE

renal impairment

intra articular agents are

analgesics, cortico

intra articular agents for what disease

OA

what is removed before intra articular agent injection

synovial effusion

max # of intra articular injections

4 per year in singular joint

OA - hyaluronic acid is normal component of

joint lubrication and nutrition

hyaluronic acid admin

3-5 injections

hyaluronic acid dec

pain for longer than other intra articular therapies

OA OTC

glucosamine, chondroitin sulfate

OA OTC do what and not what

dec pain, do not grow new cartilage

OA OTC doc reccommends

3 month trial period

RA affects more than just

joints

RA more common in

women, 3:1

RA is ___ disorder

autoimmune

RA inflamed synovium does what

invades and destroys bone and cartilage

RA characterized by

exacerbations and remissions

RA disabling morning joint stiffness

may last an hour or more

RA affects what first

fingers, hands, wrists

RA affects second

hips, knees

RA hand terms

boutonniere thumb, ulnar deviation, swan-neck fingers

rheumatoid factor

- early, + late

what determines if inflammatory process is present

ESR, CRP (erythrocyte sedimentation rate and c reactive protein)

RA cortico

prednisone 2.5-7.5mg daily

long term steroid use can cause

osteoporosis, cataracts, HTN, inc risk for infection

RA NSAID

cox 2 inhibitor (celebrex)

RA DMARDs

disease modifying antirheumatic drugs

begin DMARDs within

3 months of RA dx

DMARD ie

methotrexate

DMARD dec ___, reduce/prevent ___, preserve ___

decrease pain and inflammation, reduce/prevent joint damage, preserve structure and function of joints