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20 Cards in this Set
- Front
- Back
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Three most common GUDs
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Genital Herpes, Syphilis, Chancroid
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Chancroid Ulcer Description
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very deep, locally desctructive lesion, painful, pus filled, bleeds easily
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Genital Herpes Ulcer Description
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chronic, recurring, very shallow small clusters of ulcers, begin as vesicles or blisters, become painful
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Syphilis Ulcer Description
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single, relatively painless, firm to touch, mid size
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Bug causing syphilis
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Treponema pallidum
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Presentation of Primary Syphilis
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ulcer, single painless indurated with clear base (no blister/pus), hard sores
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Presentation of Secondary Syphilis
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wks-mos after primary infxn, fever, headache, muscle/joint pain, loss of appetite, skin rash (variable, can involve palms/soles), adenopathy, hepatitis, nephritis, aseptic meningitis
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Presentation of Tertiary Syphilis
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Benign Late Syphilis (gumma), CV syphilis, Neurosyphilis
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Describe Gumma
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benign late syphilis, gumma nodules, generally benign, can form in organs and be fatal, DTH response to organism
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Describe Cardiovascular Syphilis
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spirochetes infect small vessels in aortic wall --> aneurysms and aortic valve insufficiency
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Describe Neurosyphilis
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General Paresis: direct invasion of cerebrum by t. pallidum; Tabes Dorsalis: infection of small arteries of spinal cord
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Clinical Presentation of neurosyphilitic general paresis
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chronic meningitis, cerebral atrophy, perivascular infiltrates, psychiatric and neurologic condition
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Stages of Latent Syphilis
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Early: first year, most likely transmission; Late: after 1 year
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Describe Early Congenital Syphilis
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snuffles to sanguinous nasal discharge, variable skin rash, condyloma lata, skeletal involvement, hematological abnormalities, CNS involvement
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Describe Late Congenital Syphilis
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skeletal malformations, dental abnormalities, inflammatory lesions (interstitial keratitis), deafness, knee inflammation, neurosyphilis, paroxysmal cold hemoglobinuria
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Hutchinson's Triad
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for late congenital syphilis: Dental Findings, Interstitial Keratitis, Neural Deafness
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Lab Diagnosis of Syphilis
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Darkfield microscopy, nontreponemal tests: ab against cardiolipin antigens released from damaged tissues; Treponemal tests: detect Ab against treponemal antigens (Captia/FTA-abs); MCB: PCR
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Syphilis Treatment
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IM Pen
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Chancroid caused by
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Haemophilus ducreyi
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Clinical Presentation of Chancroid
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Single or multiple relatively deep, tender ulcers, no induration, granular base, irregular border, bleed easily, purulent, development of bubo (abscessed LN)
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