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11 Cards in this Set
- Front
- Back
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what are the advantages of amniocentesis
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widely avail
lower risk of miscarriage |
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which has higher risk of miscarriage? amnio or CVS?
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CVS
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when can you do amnio? When can you do CVS?
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CVS earlier 11-14 wks
amnio >16wks |
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are there more providers trained in amnio or CVS?
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amnio
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low sensitivity means high false ______
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neatives
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low specificity means high false _______
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positives
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what does PPV tell you
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if the test is positive, how likely is it true
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discuss a bayesian analysis
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considers prob of carrier, both parents carrier, both of them pass on disease, test probability, combining all for the hypothesis I carrier and hypothesis II not a carrier
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what is the difference between predictive and diagnostic testing
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predictive determines presence of a predisposition WITHOUT symptoms
diagnostic is done in context of history or physical exam |
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what are some potential adverse consequences of a low risk or negative results of a predictive test?
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survivor guilt
obligation to care for family members isolation from the family disease need to rebuild life limited avail resources |
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cancer is always genetic but rarely inherited... what does this mean
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cancer is multifactorial
only the predisposition can be inherited not the disease |
