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31 Cards in this Set

  • Front
  • Back
Structure is diverse (sequence)
Replicated faithfully
Mostly stable but mutable
contains information for biological structures.
Properties of DNA that make it hereditary material
In a heterozygote, when linked genes have the recessive mutant alleles on one chromosome and the wild-type alleles on the homologous chromosome, the recessive mutant alleles are said to be in
CIS conformation
Reverse genetic analysis goes from
genotype to phenotype
Forward genetic analys goes from
phenotype to genotype
These are used in genetic analysis because they produce in large numbers of progeny in a short time, studies on these help us understand featurs of inheritance, and studies on these help us understand development in general
Model Organisms
Each pea plant has a pair of each hereditary factor, each factor appears in two forms, members of each gene separate equally into pollen and eggs during reproduction, and gametes fuse randomly.
Assumptions of Mendel's model
Produced by DNA replication and are separate during mitosis
Chromatids
Results from cross pollination, produces heterozygous plants that are not pure breeding
hybrid vigor
display a range of variation, and result from 2 or more single-gene mutations
Polygenic traits
Used to determine if the deviation between observed and expected values is significant, and to determine if one should reject an hypothesis.
X^2 test
In humans, males are __________ for X-linked traits (only on one allele or chromosome)
Hemizygous
A dominant allele
Maybe dominant to wildtype
Holds bivalents together, holds homologous pairs together, holds tetrads together, forms during meiosis 1
synaptonemal complex
Mitosis growth, meiosis, and syngamy describes the relationship between mitosis and meiosis in the life cycle of
mice
Mitosis has _____ parent cells
somatic
Meiosis has parent_______
meiocytes
Contain 2 crosses between alleles of outside genes, are the smallest, don't show crossover between the alleles of the outside genes, and hsould be counted twice in determining the distance between outside markers
Double crossover classes in trihybrid mapping.
We can see the effects of crossing over when it occurs between
Nonsister chromatids
Compare the number of observed double cross overs to the expected number of cross overs.
The coefficient of coincidence.
Genotype of the tester is homozygous recessive at all three loci, the ratio of phenotypic classes in progeny deviates from expected 1:1:1:1:1:1:1:1, there are more single recombinants than double recombinants, most of the progeny display parental phenotypes
Trihybrid mapping crosses
Number of DNA double helices found in a diploid mitotic metaphase cell if n=4
16
Is Mendel's first law and is only true for alleles on the same chromosome pair
Equal segregation of alleles
G1+S+G2
Interphase
Mitosis and Meiosis always differ in regard to the presence of
bivalents
Heterozygous for two genes under study
dihybrid
typical genotype of monohybrid selfcross
1:2:1
Occurs if genes are located on different chromosome pairs
Independent assortment
homogametic
Female sex chromosomes
A linkcage map can be more than 50 cM
True
Interference is more likely to be noticable between two closely linked genes than between two distantly linked genes
true
meiotic chromosomes cannot be seen after staining nuclei from rapidly dividing skin cells.
True