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31 Cards in this Set
- Front
- Back
Structure is diverse (sequence)
Replicated faithfully Mostly stable but mutable contains information for biological structures. |
Properties of DNA that make it hereditary material
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In a heterozygote, when linked genes have the recessive mutant alleles on one chromosome and the wild-type alleles on the homologous chromosome, the recessive mutant alleles are said to be in
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CIS conformation
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Reverse genetic analysis goes from
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genotype to phenotype
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Forward genetic analys goes from
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phenotype to genotype
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These are used in genetic analysis because they produce in large numbers of progeny in a short time, studies on these help us understand featurs of inheritance, and studies on these help us understand development in general
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Model Organisms
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Each pea plant has a pair of each hereditary factor, each factor appears in two forms, members of each gene separate equally into pollen and eggs during reproduction, and gametes fuse randomly.
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Assumptions of Mendel's model
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Produced by DNA replication and are separate during mitosis
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Chromatids
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Results from cross pollination, produces heterozygous plants that are not pure breeding
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hybrid vigor
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display a range of variation, and result from 2 or more single-gene mutations
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Polygenic traits
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Used to determine if the deviation between observed and expected values is significant, and to determine if one should reject an hypothesis.
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X^2 test
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In humans, males are __________ for X-linked traits (only on one allele or chromosome)
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Hemizygous
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A dominant allele
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Maybe dominant to wildtype
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Holds bivalents together, holds homologous pairs together, holds tetrads together, forms during meiosis 1
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synaptonemal complex
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Mitosis growth, meiosis, and syngamy describes the relationship between mitosis and meiosis in the life cycle of
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mice
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Mitosis has _____ parent cells
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somatic
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Meiosis has parent_______
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meiocytes
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Contain 2 crosses between alleles of outside genes, are the smallest, don't show crossover between the alleles of the outside genes, and hsould be counted twice in determining the distance between outside markers
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Double crossover classes in trihybrid mapping.
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We can see the effects of crossing over when it occurs between
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Nonsister chromatids
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Compare the number of observed double cross overs to the expected number of cross overs.
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The coefficient of coincidence.
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Genotype of the tester is homozygous recessive at all three loci, the ratio of phenotypic classes in progeny deviates from expected 1:1:1:1:1:1:1:1, there are more single recombinants than double recombinants, most of the progeny display parental phenotypes
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Trihybrid mapping crosses
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Number of DNA double helices found in a diploid mitotic metaphase cell if n=4
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16
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Is Mendel's first law and is only true for alleles on the same chromosome pair
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Equal segregation of alleles
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G1+S+G2
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Interphase
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Mitosis and Meiosis always differ in regard to the presence of
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bivalents
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Heterozygous for two genes under study
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dihybrid
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typical genotype of monohybrid selfcross
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1:2:1
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Occurs if genes are located on different chromosome pairs
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Independent assortment
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homogametic
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Female sex chromosomes
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A linkcage map can be more than 50 cM
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True
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Interference is more likely to be noticable between two closely linked genes than between two distantly linked genes
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true
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meiotic chromosomes cannot be seen after staining nuclei from rapidly dividing skin cells.
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True
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