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19 Cards in this Set
- Front
- Back
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Prednisone |
Corticosteroid
Uses: Inhibit immune mediated disease responses
Ex. MMM |
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Azathioprine |
Immunosuppressive drug used in autoimmune disease
Side effect: Bone marrow suppression
Ex. MMM, IBD |
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Cisapride |
Gastroprokinetic agent: Increases motility in the upper GIT (increases gastric emptying, therefore decreasing amount of gastric acid in stomach and the amount that can reflux)
Ex. Gastroesophageal reflux w/ megaoesophagus |
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Omeprazole |
Proton Pump Inhibitor (PPI): Decrease the amount of gastric acid produced in the stomach by inhibition of the H +/K + ATPase pump found in gastric parietal cells.
Ex. Gastroesophageal reflux, promoting healing of oesophageal mucosa with oesophagitis, gastric ulcer |
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Metaclopramide |
Dopamine and Serotonin-receptor antagonist: Anti-emetic (antagonism of CRTZ, gastric prokinetic agent and increased LES tone
Ex. Oesophagitis, vomiting, increased gastric motility, gastroesophageal reflux |
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Sucralfate |
Cytoprotective agent: Binds to mucosa, creating a physical barrier that impairs diffusion of HCl- in the GIT, preventing degradation of mucus by acid & stimulates HCO3- output acting like an acid buffer
Ex. Gastroesophageal reflux, GIT ulcers, oesophagitis |
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Pilocarpine |
Parasympathomimetic: Miosis
Ex. Confirming dysautonomia |
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Bethanecol |
Parasymptahomimetic: Miosis, bladder detrusor m. contraction and expulsion of urine, increased GIT motility
Ex. Dysautonomias, urinary retention |
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Ranitidine |
H2-receptor antagonist: Inhibits stomach acid production
Ex. Ulcers, gastroesophageal reflux, esophagitis, gastritis, dysautonomias |
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Maropitant/Cerenia |
Neurokinin (NK1) receptor antagonist: Anti-emetic
Ex. Vomiting, GIT inflammation, motion sickness |
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Famotidine |
Histamine H2 receptor antagonist: Inhibits stomach acid production
Ex. Ulcers, GEreflux, idiopathic inflammatory gastritis |
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Misoprostol |
Synthetic prostaglandin analogue: Prevent gastric ulcers by inhibiting the secretion of gastric acid by GPCR-mediated inhibition of AC, which leads to decreased intracellular cAMP & decreased proton pump activity at the apical surface of the parietal cell.
Ex. Gastric ulcers/NSAID toxicity |
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Amoxicillan |
Aminopenicillin antibiotic: Mostly Gram + with some Gram - activity, oral admin
Ex. Helicobacter gastritis |
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Metronidazole |
Nitroimidazole antibiotic: Anaerobes and protozoa
Ex. Helicobacter gastritis |
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Pyrantel pamoate |
Depolarizing neuromuscular blocking agent: Causing contraction, followed by paralysis, helminths. Not absorbed in GIT so good for GIT parasites
Ex. Parasitic gastritis: Physaloptera in dogs |
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Fenbendazole |
Broad spectrum bezimidazole anthelmintic used against GIT parasites
Ex. Parasitic gastritis: Ollulanus in cats, giardia |
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Tylosin |
Macrolide bacteriostat feed additive: Gram + mainly by inhibition of protein synthesis by binding to the 50S subunit of the bacterial ribosome. Removes unwanted bacteria and restores normal GI flora.
Ex. Antibiotic responsive diarrheoa and IBD |
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Chlorambucil |
Alkylating agent/chemotherapeutic drug: Cause immunosuppression (can cause bone marrow suppression)
Ex. IBD (cats) and feline GI small cell lymphoma |
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Cyclosporine |
Immunosuppressant drug: Lowers the activity of T cells and their immune response
Ex. IBD (dogs) |
