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50 Cards in this Set

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Stomach purpose

Digests food and prepares nutrients for absorption.

Acts as a reservoir

Stomach parts

Cardia, fundus, body, & antrum

Lesser and greater curvatures

Pylorus

Portion near Duodenum

Pyloric sphincter

Omentum

Coverall peritoneum covers the exterior of the stomach.

Greater & Lesser omentum

Rugae

Wrinkled ridges of the interior stomach.

Allow for expansion

Arterial blood supply to stomach

Celiac axis

Vagus nerve

Parasympathetic innervation is via the vagus nerve.

Dual purpose of vagus nerve

Fundus & body promotes stimulates acid secretion

Antrum stimulates motility

Cardiac glands

Secrete mucus and pepsinogens

HCl acid converts to pepsin

Oxyntic gland areas 4 types

Chief cells- zymogen


Parietal cells-

G cells

Gastrin secretion

Enterochromaffin cells

Secrete serotonin

Somatostatin & glucagon production


Produced by nine different endocrine cells by the mucosa

ie, Cardiac, oxyntic, & pyloric mucosa

Chyme

Good bolus mixes with digestive juices

Creates a semi liquid

Gastric emptying rate

Controlled by neural impulses, composition of the chyme and by hormones is the small intestine

Ulcers

Gastric inflammation

Mechanical, chemical, infectious, or ischemic nature

Helicobacter pylori

Infection, risk factor

Gastric ulcer risk factors

H. Pylori


Salicylates, NSAIDS


Family history


Cigarette smoking


Peptic ulcer complications

Hemorrhage 15%


Perforation. 7%


Obstruction

S/s upper abd pain, guarding, rebound tenderness, absent bs.

Penetration and perforation

Pathologically similar.


S/s back pain, night distress, epigastric pain.

Surgical intervention.


Obstruction of gastric outlet r/t scaring at GE jct.

Gastric obstruction s/s

Abdominal distension


Tympany succussion splash


Vomiting


Early satiety


Vague abd pain

Tx NG tube decompression


Fluid, electrolyte rebalance


H2 blockers


Surgery

Bacteria H. Pylori inveftion less to gastritis, gastric & Duodenum ulcers.

Has adapted to and avoids the acidic nature of the stomach by burrowing beneath the mucosa and Duodenum.

Transmission via fecal/oral route

Culture is gold standard

H. Pylori dx

Eradication, combo of drugs. Compliance, effectiveness, and economic considerations

Gastric cancer

Hereditary, blood type A, lower socioeconomic status. Black> white, North USA, men>women.

Certain foods, ulcers, surgery, achlorhydria, pernicious anemia, intestinal metaplasia, adenomatous polyps,

Gastric ca s/s

Epigastric discomfort, vomiting, occult blood. Weight loss, early satiety, anorexia, anemia, mass, outlet obstruction, acities, lymph nodes.

Mets: direct to omentum, liver, pancreas, spleen, transverse colon.

Mets: 4 routes

1 Direct extension


2 Lymphatic to nodes


3 Hematogenous to liver, lungs, bone or cns.


4 peritoneal to pelvis

May see hypoalbuminemia

5 yr. Survival rate gastric ca

95% if limited to mucosa or sub mucosa.

Early detection best. Linitis plastica is worst

Polyp

Any circumscribed, discrete stomach tumor

Polyp types

1. Hyperplastic


2. Adenomas


3. Leiomyoma


4. Adenomyomas

1. Most common, always benign


2. -


3. Smooth muscle


4. Hamartomas, benign mixtures

Superficial gastritis

Path change limited to upper 1/3

Atrophic gastritis

Full thickness of mucosa, producing atrophy of gastric glands. Loss of chief and parietal cells.

Gastric atrophy

Marked or total gland loss but little inflammation, and the mucosa is thinned.

NNG

Non-erosive, non-specific gastritis

Common with aging, gastric ulcers, pernicious anemia, cancer, or h. Pylori

Pernicious anemia

Tx vit B12

Curling's Ulcer

Significant burn injuries pt.

Cushing's Ulcer

Intracranial trauma, head injuries, craniotomy

Stress ulcers

Serve trauma, ongoing sepsis, serious illness

Chronic drug ingestion ulcer

NSAIDS, alcohol

Gastric varicies

Occurs in 2/3 of eso varicies. Higher mortality. 90% reoccurrence.

Portal htn and collateral circ pressure

Varicies objectives

1. Hemodynamic stability


2. Stop bleeding


3. Reduce portal pressure via shunt. Or TIPS

Transjugular intrahepatic portosystemic shunt

Hiatal hernia

Stomach protrudes through diaphragm into thoracic cavity

Sliding, weakened LES & GERD

Infantile hypertrophic pyloric stenosis

Age 6 wks. Boys. Familial. projectile vomiting.


Dx ultrasound. Tx pyloromyotomy

Dehydration, electrolyte imbalances, metabolic alkalosis, hypokalemia.

Atresias

Blind ends or occlusions

Microgastria or hypoplasia

Stomach never differentiates into true fundus, body and pylorus

Gastric duplication

Mass lesion with all stomach layers

Occurs in stomach

Neonatal perforations

Assoc with prematurity, peptic ulcers, distal sm intestine obst

Dumping syndrome

Rapid emptying w/ group symptoms. Anxiety, weakness, dizziness, tachycardia, diaphoresis, flushing, cramps, and diarrhea.

Symptoms can result from hypoglycemia. LOC may occur

Gastric outlet obstruction

Obst of pyloric sphincter.


Tx restore fluid & electrolyte balance, decompression of stomach, correct nutrition deficiency. Dilatation of pylorus.

Caustic injury

Alkaline agent causes liquefactive necrosis. Acids primate coagulation necrosis.

Mouth& ESO. Gastric perforation leads to mediastinitis, peritonitis, shock

Bezoars

Concretions of foreign material found in stomach

Result in anorexia, vomiting, ulceration, bleeding, perforation, obstruction