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10 Cards in this Set
- Front
- Back
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histoplasma capsulatum
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ascomycete
dimorphic h and e stain, PAS stain, methenamine silver stain macro/microconidia mississippi avian bat feces can reside in M phage enlargement of reticuloendothelial organs with young elderly immunocompromised skin test 2-5 wks not good for endogenous people look for yeast within mphage amphotecerin b itraconazole |
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coccidoides immitis
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valley fever- flu like meningeal involvement, skin lesions
cxr: eggshell skin test 1-2 wks precipitation and complement fixing AB apheres and endospheres/ rupture to release dimorphic airborne arthroconidia dustclouds, earthquakes |
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blastomyces dermatitis
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broad based budding yeast
dimorphic rural of SE and Central lobar pneumonia--> disseminates SKIN LESIONS papular ulcerated |
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paracoccidoides brasiliensis
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parent cell with peripheral buds
dimorphic south american warm wet, lobar pneumonia that disseminates |
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aspergillus
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opportunistic
ascomyocete filamentous fungus septate hyphae 45 branching secretes protinases whcih inhibit mucociliary sustem phagocytosis causes: 1: acute asthma rxn alergic bronchopulmonary aspergillosis type 1-3 arthus fungus ball pulmonary invasive aspergillosis risk fxs CF TB sarcoidosis cavitary CA neutropenia corticosteroid and itraconazole |
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zygomycetes
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opportunistic nonseptate hyphae 90 branch
=mucormycosis preferential to CNS entry through nose, eyes palate risk fxs DKA increased FE burn pts immuno def |
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Mycobacterium tuberculosis
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rod shaped obligate anaerobe
heat sensitive produce niacin acid fast stain facultive intracellular parasite sulfatides: inhibit phagosome lysosome fusion. inhabits mphage LAM: decreases mphage active resp. droplet nuclei insidious onset, fever weight loss, blood tinged sputum culture on lowenstein jensem, middlebrook or liquid broth mantoux test anergy with HIV INH rifampin,pyrazinimide, ethambutol etc. BCG vaccination, not in US |
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MAC
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only treated with rifabutine
and cipro NOT P2P in water and soil dissemination common |
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m kansasii
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NOT P2P water and soil
ppd x reactivity |
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nocardia
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beady gram positive
aerobe patially acid fast filamentous found in soil lung abscesses and BRAIN ABSCESSES sulfonimides |
