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6 Cards in this Set

  • Front
  • Back

Ideal suicidal poison

Cheap


Easily available


Highly toxic


Tasteless or pleasant in taste


Mix with food , drinks


Capable of causing painless death

Chronic lead poisoning

Symptoms:--


Facial pallor


Anemia:- basophilic stippling, eosinophilia


Lead line: burtonian line


Wrist and foot drop. ( lead palsy)


Encephalopathy


Black foot syndrome


Colic and constipation


Pure motor neuropathy



Rx:- succimer


Ca EDTA + Bal


Arsenic poisoning

Fulminant :--- direct action on heart


Acute:- 1) Gastroenteric form


Sym:- throat pain, vomiting , purging


2) narcotic form


Chronic :-- 1) hair:- golden hair-- alopecia


2) skin :- hyperkeratosis-- Bowen's disease--- BCC


3) Nail: Aldrich meds line


4) bones:- pancytopenia , burnt bones




Dx:-- gastric lavage with hydrated ferric oxide


Postmortem :- stomach :- red velvetty


Heart :- sub endocardial he.

Posionous compounds of arsenic and MOA

Arsenious oxide/ar senic trioxide/white arsenic


Copper arsenite (scheele's green), arsenic acid, sod and k arsenate, arsenic sulphide


Arseniuretted hydrogen



MOA:-- it interferes with cellular respiration by combining with the sh group of mitochondrial enzymes.


Causes it's toxicity by uncoupling Mito. Oxidative posphorylation


Target tissue:- vascular endothelium

chroinic Poisoning of mercury

Danbury temors


hatter's shake or glass blower's shake


Concussion mercurialis


Mercuric erethism :- mirror firms


Mercurilentis :- brown deposit in eyes


Acrodynia or pink disease :- generalized body rash

Emetics contraindications

Severe heart and lungs disease


Advanced pregnancy


After ingestion of CNS stimulant


Same as for stomach wash