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85 Cards in this Set

  • Front
  • Back

Solute

The substance dissolved in a given solution

Solvent

the liquid in which a solute is dissolved to form a solution

Diffusion

-Movements of solutes across a semipermable membrane down concentration gradients


-Membrane seperating two areas must be permeable to substance for diffusion to occur

Osmosis

-Movement of water between two compartments by a membrane permeable to water but not to solutes.


- Water moves from one area of lesser solute concentration to a greater solute concentration


- Major method of transporting fluids

Filtration

The passage of fluid thru permable membrane- fluids move from an area of high pressure to one of lower pressure

Tonicity

Measure of effective osmostic pressure of two solutions.

Hypotonic

Lesser concentration of particles than plasma- causes a cell to burst.

Isotonic

Has the same concentration of particles to plasma

Hypertonic

Has greater concentration of particles than plasma because water moves out of the cell- causes cell to shrink.

Osmolarity

Concentration of particles in a solution

Hydrostatic Pressure

-Major force that pushes water out of vascular system at capillary level.


-The "pushing" force

Osmotic Pressure (oncotic)

-The Pulling force


- Osmotic pressure exerted by colloids in solution


- Protein is major colloid in vascular system


Crystalloid

A substance that when dissolved, forms a true solution and is able to pass through a semipermable membrane.

Colloid

A large solute particle such as plasma proteins

Intracellular Fluid ICF

-Fluid within the cells


- 70% of body wt/40% of adults weight

Extracellular Fluid ECF

-Fluid is all the fluid outside the cells; 30% of total body wt/20% adult body wt


-2 major components- Intravascular & Interstitial fluid


-Transcellular

Intravascular Fluid

Plasma in the liquid compnent of blood

Interstitial Fluid

Surrounds tissue cells and lymph

Transcellular Fluid

small amount of fluid in: Cerebrospinal, pericardial, pericardial, synovial fluids, peritoneal spaces

Sources of Fluid for the body

- Ingested Fluids


- Food


- Products of metabolism

Permability

the state or quality of a material or membrane that causes it to allow liquids or gases to pass through it.

Semipermeable

allowing certain substances to pass through it but not others, especially allowing the passage of a solvent but not of certain solutes.

Active Transport

-Process in which molecule move against concentration gradient


- ATP is energy source

Edema is the result of.....

-Plasma (vascular space) to interstitial fluid shift


- Elevation of hydrostatis pressure


- decrease in plasma oncotic pressure


-Elevation of interstitial oncotic pressure

Hypovolemia

-Isotonic Fluid Loss


-Loss of both water and solutes in the same proportion from the ECF space

Interstitial Fuild to Plasma Fluid Shift

- Wearing compression stockings or hose is therapeutic action on this effect

Fluid Spacing

- First Spacing: Normal distribution of fluid in the ICF and ECF


- Second Spacing: Abnormal accumulation of Interstitial Fluid- LEADS TO EDEMA


- Third Spacing- Abnormal Distributional shift of body fluids into transceullar compartments ex) ascites

Fluid Volume Deficit

- Abnormal loss thru skin, gi tract, kidney, burns


- 3rd spacing


- Sx: Dehydrated, Fatigue, Wt loss, dark urine, heart palpatation, weak pulse, poor skin turgor, sunken eyeballs, low output, BUN/Hct/Specific gravity will be elevated, confusion


- Nursing Intervention: Strict i&o, Daily wts, HOB 30 Degrees or less- water to brain, monitor vascular, respiratory

Fluid Volume Excess

- Excessive intake of sodium


-Pts at risk: CHF


-Sx: Increase RR, SOB, wt gain, seizure, coma, bounding pulse, crackles(lung sounds), Taut skin, BUN/Hct/Specific gravity low, Confusion


Rx: Diuretics fluid/sodium restriction


Nursing Interventions: Daily Wts, High fowlers (Easy breathing)

Hypoproteniemia

- Low Protein


- Caused by: Anorexia, Malnutrition


-Clinical Manifestations: Edema, slow healing, anemia, muscle loss, ascites


-Managment: High carb/protein diet, TPN/Enteral nutrition

Renal Regulation

- Kidneys are primary organs for regulating fluid and electrolyte balance


- Excretion of electrolytes occures


-Renal tubules are sites of action of ADH and Aldosterone


-Selective reabsoption of water and electrolytes

Hypothalamic Regulation

- Osmoreceptors in hypothalamus sense fluid deficit or increase in plasma osmolality


-Stimulate Thirst and antidiuretic hormone (adh) Release


- Result in increased free water

Pituitary Regulation

-Under control of hypothalamus, posterior pituitary releases ADH


- Stress nausea nictine and morphine also stimulate ADH release

Adrenal Cortical Regulation

-Adrenal cortex releases hormones to regulate both water and electrolytes


1. Glucocorticoids


2. Mineralcorticoids



Aldosterone is a mineralcorticoid with potent sodium- retaining and potassium excreting capability.

1 KG of weight (2.2 lbs) = _____ Of fluid

1 Liter

Respiratory Acidosis

- Increased Hydrogen ion concentration


- blood ph < 7.35


-Excess of carbonic acid


- Causes: anything that causes hypoventilation

Respiratory Alkalosis

- Decreased hydrogen ion concentration


- blood ph > 7.45


- decrease in carbonic acid


- Causes: hyperventilation

Metabolic acidosis

- Increase hydrogen ion or decrease in bicarbonate concentration


- Blood ph < 7.35


- Causes: chronic diarrhea, renal failure, DKA, drug overdose

Metabolic Alkalosis

- Loss of hydrogen ion os gain in base


- blood ph > 7.45


- Causes: excess intake of antacids, vomitting, or NG Suctioning

Sodium

- Lab values: 135-145 mEq/L


- Water balance, osmotic pressure of ECF, nueromuscular irritability, acid/base


- Attracts water


-Regulated in ECF by aldosterone and renal blood flow


-Neurological changes

Hypernatremia

- Due to decrease in water intake or increase in sodium intake


- High protein feedings with out water


- Sx: Intense Thirst, tenting, agitated, confused


- Rx: Tx underlying cause, isotonic to restore volume or hypotonic fluids, must reduse sodium levels gradulaly to avoid cerebral edema

Hyponatremia

- Most commmon electrolyte imbalance


- increase sodium excretion


-dilution of serum sodium


- results from loss of Na containing fluids or from excesss water


Sx: mental confusion, edema, wt gain


Rx: Loop diuretics, 0.9NS, foods with Na

Management of Hyponatremia

- Fluid restriction if caused by excess water


- If severe sx (seizure) occur, small amt of IV Hypertonic saline solution 3%NaCl is given


-If associated with fluid loss need to replace with appropriate fluids

Potassium

- Lab Values: 3.5-5.0 mEq/L


-Depolarization/repolarization of cardiac and skeletal muscle


-Major cation of ICF


- Metabolism of CHO and proteins(insulin and potassium are necessary to move glucose into the cells)

Hyperkalemia

- Hydrogen ion moves into the cell and pushes potassium out - Caused by excessive intake, renal failre, drugs, salt substitutes


- sx: Arrythmias, muscle cramps


- rx: Kayexalate- binds with k or insulin and glucose- moves k back in the cell - loop diuretics, dialyisis, calcium gluconate, IV sodium bicardbonate/IV insulin


- monitor ecg, electrolytes


HypoKalemia

- decreased intake, increase in renal excretion, gi excretion, diuretics


- sx: decrease function of muscles in heart, lung, GI


- rx: oral relplacement, iv replacement (no more than 10 meq/h)


- NEVER give iv push, monitor digoxin levels

Calcium

- lab values: 4.5-5.5 meq/l or 8.6-10 mg/dl


- most ca in bones and teeth


- only 1% is intravascular


- regulated by parathyyroid hormone (pth), calcitonin and vit d


- when hydrogen ions falls (alkalosis) more calcium is bound to protein- does not work

Hypercalcemia

- Causes: hyperparathyroidism, malginancy, prlong immobility


- sx: bone pain, flank pain, dysrrhythmias, personality changes


- RX: ivs, diuretics, calcitonin (promotes reuptake in the bones), weight bearing


- straing urine for calculi

Hypocalcemia

- renal failure, malabsorption


- sx: tetany, parethesia of lips and extremities, chvosteks sx, trousseau's sx, altered clotting, bradycardia


- rx: calcium gluconate


- seizure precautions


Magnesium

- Lab Values: 1.5-2.5 mEq/l


- Intracellular


- Eliminated by kindeys


-Magnesium and potassium levels increase/decrease together


-Causes cardiac arrest

Hypermagnesemia

- Renal Dysfunction or intake of antacids


- Premature labor or pregnancy induced hypertension


- sx: muscular weakness, hypotension, dimished reflexes, sedative effect


- rx: serium calcium, antagonizes magnesium; renal hydration, diuretics, IV calcium gluconate


-Nursing inteventions: assess DTR's

Hypomagnesemia

- usually kypokalemia or hypocalcemia, also alcoholics


-malabsorption, diarrhea, vomiting, bowel surgery, diuretics


-Sx: increased neuromuscular irritability, personality changes, seziures, tachycardia


-Rx: Magnesium replacement- oral or iv; avoid magnesium-based antacids/laxatives


-Nursing intevertions: assess for chvosteks and trousseau signs, seizure precautions

Hypovolemia

-can occur with loss of normal body fluids (diarrhea, fistual drainage, hemorrhage), decreased intake, or plasma-tointerstitial fluid shift


-S/S: Tachycardia, delayed capillary fill, decreased bp, thirst, orthostatic hypotension


-tx: balanced iv fluids, isotonic chloride, or blood

Hypervolemia

- may result from excessive intake of fluids, abnormal retention of fluids (chf) or interstitial to plasma fluid shift


- s/s: Rapid bounding pulse, edema, wheezes and crackles, distended nack veins


-tx: diuretics, fluid restriction, and sodium restriction

Urine pH and Specific Gravity Values

Range for pH- 4.6-8.2


SG: 1.005-1.010

Isotonic Fluids

- d5w (dextrose in water) - in a bag


-.9% NaCl (normal saline)


-Lactated ringers (lr)

Hypotonic fluids

- .45% ns (1/2 strength of NS)


Hypertonic Fluids

-D5.45%NSS


-D10%W


-D2.25%NS


-D5.9%NSS

Infiltration

- Escape of fluid into subcutaneous tissue


-dislodged cannula


-penetrated vessel wall


-Swelling, edema, pallor, coldness or pain around infusion


-D/C, Restart IV

Phlebitis

- inflammation of a vein related to a chemical, mechanical or bacterical irritation


- Mechanical: from needle or cath


-Chemical: related to infusate


-Bacterial: poor aseptic tech/contamination


-Red, warm, pain, swelling

Normal saline

- 0.9% NaCl in water


- Isotonic


-Increases circulating plasma volume when red cells are adequate


-Replaces losses without altering fluid concentrations


Helpful Na+ replacement

1/2 Normal Saline

- .45% NaCl in water


-Hypotonic


- Raises total fluid volume


- Useful for daily maintenance of body fluid, helpful for establishing renal function, fluid replacement for clients who dont need extra glucose (diabetics)

Lactacted ringers (LR)

-Normal Saline with electrolytes and buffer


- isotonic


- replasces fluid and buffers pH


- normal saline with k+, ca++, and lactate (buffer)


-Often seen with surgery

D5W

- DEXTROSE 5% in 0.9% saline


-isotonic (in bag) Physiologically hypotonic


-Raises total fluid volume, helpful in hydrating and excretory purposes


-Provides 170-200 calories/1000cc for energy

S1 Heart Sound

- At the beginning of systole (end of diastole).


- Related to the closure of the mitral and tricuspid valves.


S2 Heart Sound

- At the beginning of Diastole (end of systole).


- Related to the closure of the aortic and pulmonic valves.

S3 Heart Sound

- Ken-tuc-ky- extra sound can be normal in children, late pregnancy or High CO; rarley heard in older adults- associated with CHF

S4 Heart Sound

- ten-nes-see- extra sound can be normal in athletes and elderly- usually abnormal assocaited with CAD, HTN,MI, Aortic or pulmonic stenosis

Preload

degree of stretch on the ventricles

Afterload

it is the aortic pressure the l ventricle muscle must overcome to eject blood

Sites for Cardiac Ausculations

1. Aortic- second r intercostal space


2. Pulmonic- second l intercostal space


3. Erb's Point- 3rd l intercostal space


4. Tricuspid- 4th l intercostal space


5. Mitral- 5th l intercostal space

MONA

-moprhine


-oxygen


-nitroglycerin


-aspirin

Systole

the phase of the heartbeat when the heart contracts and pumps blood from the chambers into the arteries

Diastole

The pahse of the hearbest when the muscle relaxes and allows chambers to fill with blood

Palpitation

A noticable rapid, strong, or irregular heartbeat

Murmur

abnormal sound during heartbeat cycle, such as whooshing or swishing- made by turbulent blood in or near your heart

Atreriosclerosis

the thickening and hardening of the walls of the arteries

Atherosclerosis

deposition of plaques of fatty material on their inner walls

Bruit

the unusual sound that blood makes when it rushes past obstruction (called turbulent flow) in an artery when the sound is ausculated with the bell portion of the stethoscope

Function of the lymphatic system

-Maintain fluid and protein balance


- Fight infections


PItting Edema Scale

+1 slight pitting, 2 mm depression


+2 increasing pitting, 4mm depression


+3 deeper pitting, 6 mm depresion, obvious


+4 severe pitting, 8mm depression

Peripheral pulse sites

1. Temporal


2. carotid


3. brachial


4. radial


5. femoral


6. Popliteal


7. posterior tibial


8.pedal

Grading of Pulses

0 absent


+1 weak, thready


+2 weak


+3 normal


+4 bounding

Blood tests to evaluate risks for PAD

-Arterial Disease:


Lipid levels


HgB A1C for diabetic patients


C reactive protein and homeosysteine levels


-Venous:


D-Dimer

6 p's of arterial occlusion

Pain


Pallor


Pulselessness


Poikilothermic (coldness)


Paralysis


Paresthesia