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85 Cards in this Set
- Front
- Back
Solute |
The substance dissolved in a given solution |
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Solvent |
the liquid in which a solute is dissolved to form a solution |
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Diffusion |
-Movements of solutes across a semipermable membrane down concentration gradients -Membrane seperating two areas must be permeable to substance for diffusion to occur |
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Osmosis |
-Movement of water between two compartments by a membrane permeable to water but not to solutes. - Water moves from one area of lesser solute concentration to a greater solute concentration - Major method of transporting fluids |
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Filtration |
The passage of fluid thru permable membrane- fluids move from an area of high pressure to one of lower pressure |
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Tonicity |
Measure of effective osmostic pressure of two solutions. |
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Hypotonic |
Lesser concentration of particles than plasma- causes a cell to burst. |
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Isotonic |
Has the same concentration of particles to plasma |
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Hypertonic |
Has greater concentration of particles than plasma because water moves out of the cell- causes cell to shrink. |
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Osmolarity |
Concentration of particles in a solution |
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Hydrostatic Pressure |
-Major force that pushes water out of vascular system at capillary level. -The "pushing" force |
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Osmotic Pressure (oncotic) |
-The Pulling force - Osmotic pressure exerted by colloids in solution - Protein is major colloid in vascular system
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Crystalloid |
A substance that when dissolved, forms a true solution and is able to pass through a semipermable membrane. |
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Colloid |
A large solute particle such as plasma proteins |
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Intracellular Fluid ICF |
-Fluid within the cells - 70% of body wt/40% of adults weight |
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Extracellular Fluid ECF |
-Fluid is all the fluid outside the cells; 30% of total body wt/20% adult body wt -2 major components- Intravascular & Interstitial fluid -Transcellular |
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Intravascular Fluid |
Plasma in the liquid compnent of blood |
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Interstitial Fluid |
Surrounds tissue cells and lymph |
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Transcellular Fluid |
small amount of fluid in: Cerebrospinal, pericardial, pericardial, synovial fluids, peritoneal spaces |
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Sources of Fluid for the body |
- Ingested Fluids - Food - Products of metabolism |
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Permability |
the state or quality of a material or membrane that causes it to allow liquids or gases to pass through it. |
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Semipermeable |
allowing certain substances to pass through it but not others, especially allowing the passage of a solvent but not of certain solutes. |
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Active Transport |
-Process in which molecule move against concentration gradient - ATP is energy source |
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Edema is the result of..... |
-Plasma (vascular space) to interstitial fluid shift - Elevation of hydrostatis pressure - decrease in plasma oncotic pressure -Elevation of interstitial oncotic pressure |
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Hypovolemia |
-Isotonic Fluid Loss -Loss of both water and solutes in the same proportion from the ECF space |
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Interstitial Fuild to Plasma Fluid Shift |
- Wearing compression stockings or hose is therapeutic action on this effect |
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Fluid Spacing |
- First Spacing: Normal distribution of fluid in the ICF and ECF - Second Spacing: Abnormal accumulation of Interstitial Fluid- LEADS TO EDEMA - Third Spacing- Abnormal Distributional shift of body fluids into transceullar compartments ex) ascites |
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Fluid Volume Deficit |
- Abnormal loss thru skin, gi tract, kidney, burns - 3rd spacing - Sx: Dehydrated, Fatigue, Wt loss, dark urine, heart palpatation, weak pulse, poor skin turgor, sunken eyeballs, low output, BUN/Hct/Specific gravity will be elevated, confusion - Nursing Intervention: Strict i&o, Daily wts, HOB 30 Degrees or less- water to brain, monitor vascular, respiratory |
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Fluid Volume Excess |
- Excessive intake of sodium -Pts at risk: CHF -Sx: Increase RR, SOB, wt gain, seizure, coma, bounding pulse, crackles(lung sounds), Taut skin, BUN/Hct/Specific gravity low, Confusion Rx: Diuretics fluid/sodium restriction Nursing Interventions: Daily Wts, High fowlers (Easy breathing) |
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Hypoproteniemia |
- Low Protein - Caused by: Anorexia, Malnutrition -Clinical Manifestations: Edema, slow healing, anemia, muscle loss, ascites -Managment: High carb/protein diet, TPN/Enteral nutrition |
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Renal Regulation |
- Kidneys are primary organs for regulating fluid and electrolyte balance - Excretion of electrolytes occures -Renal tubules are sites of action of ADH and Aldosterone -Selective reabsoption of water and electrolytes |
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Hypothalamic Regulation |
- Osmoreceptors in hypothalamus sense fluid deficit or increase in plasma osmolality -Stimulate Thirst and antidiuretic hormone (adh) Release - Result in increased free water |
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Pituitary Regulation |
-Under control of hypothalamus, posterior pituitary releases ADH - Stress nausea nictine and morphine also stimulate ADH release |
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Adrenal Cortical Regulation |
-Adrenal cortex releases hormones to regulate both water and electrolytes 1. Glucocorticoids 2. Mineralcorticoids
Aldosterone is a mineralcorticoid with potent sodium- retaining and potassium excreting capability. |
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1 KG of weight (2.2 lbs) = _____ Of fluid |
1 Liter |
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Respiratory Acidosis |
- Increased Hydrogen ion concentration - blood ph < 7.35 -Excess of carbonic acid - Causes: anything that causes hypoventilation |
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Respiratory Alkalosis |
- Decreased hydrogen ion concentration - blood ph > 7.45 - decrease in carbonic acid - Causes: hyperventilation |
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Metabolic acidosis |
- Increase hydrogen ion or decrease in bicarbonate concentration - Blood ph < 7.35 - Causes: chronic diarrhea, renal failure, DKA, drug overdose |
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Metabolic Alkalosis |
- Loss of hydrogen ion os gain in base - blood ph > 7.45 - Causes: excess intake of antacids, vomitting, or NG Suctioning |
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Sodium |
- Lab values: 135-145 mEq/L - Water balance, osmotic pressure of ECF, nueromuscular irritability, acid/base - Attracts water -Regulated in ECF by aldosterone and renal blood flow -Neurological changes |
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Hypernatremia |
- Due to decrease in water intake or increase in sodium intake - High protein feedings with out water - Sx: Intense Thirst, tenting, agitated, confused - Rx: Tx underlying cause, isotonic to restore volume or hypotonic fluids, must reduse sodium levels gradulaly to avoid cerebral edema |
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Hyponatremia |
- Most commmon electrolyte imbalance - increase sodium excretion -dilution of serum sodium - results from loss of Na containing fluids or from excesss water Sx: mental confusion, edema, wt gain Rx: Loop diuretics, 0.9NS, foods with Na |
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Management of Hyponatremia |
- Fluid restriction if caused by excess water - If severe sx (seizure) occur, small amt of IV Hypertonic saline solution 3%NaCl is given -If associated with fluid loss need to replace with appropriate fluids |
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Potassium |
- Lab Values: 3.5-5.0 mEq/L -Depolarization/repolarization of cardiac and skeletal muscle -Major cation of ICF - Metabolism of CHO and proteins(insulin and potassium are necessary to move glucose into the cells) |
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Hyperkalemia |
- Hydrogen ion moves into the cell and pushes potassium out - Caused by excessive intake, renal failre, drugs, salt substitutes - sx: Arrythmias, muscle cramps - rx: Kayexalate- binds with k or insulin and glucose- moves k back in the cell - loop diuretics, dialyisis, calcium gluconate, IV sodium bicardbonate/IV insulin - monitor ecg, electrolytes
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HypoKalemia |
- decreased intake, increase in renal excretion, gi excretion, diuretics - sx: decrease function of muscles in heart, lung, GI - rx: oral relplacement, iv replacement (no more than 10 meq/h) - NEVER give iv push, monitor digoxin levels |
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Calcium |
- lab values: 4.5-5.5 meq/l or 8.6-10 mg/dl - most ca in bones and teeth - only 1% is intravascular - regulated by parathyyroid hormone (pth), calcitonin and vit d - when hydrogen ions falls (alkalosis) more calcium is bound to protein- does not work |
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Hypercalcemia |
- Causes: hyperparathyroidism, malginancy, prlong immobility - sx: bone pain, flank pain, dysrrhythmias, personality changes - RX: ivs, diuretics, calcitonin (promotes reuptake in the bones), weight bearing - straing urine for calculi |
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Hypocalcemia |
- renal failure, malabsorption - sx: tetany, parethesia of lips and extremities, chvosteks sx, trousseau's sx, altered clotting, bradycardia - rx: calcium gluconate - seizure precautions
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Magnesium |
- Lab Values: 1.5-2.5 mEq/l - Intracellular - Eliminated by kindeys -Magnesium and potassium levels increase/decrease together -Causes cardiac arrest |
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Hypermagnesemia |
- Renal Dysfunction or intake of antacids - Premature labor or pregnancy induced hypertension - sx: muscular weakness, hypotension, dimished reflexes, sedative effect - rx: serium calcium, antagonizes magnesium; renal hydration, diuretics, IV calcium gluconate -Nursing inteventions: assess DTR's |
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Hypomagnesemia |
- usually kypokalemia or hypocalcemia, also alcoholics -malabsorption, diarrhea, vomiting, bowel surgery, diuretics -Sx: increased neuromuscular irritability, personality changes, seziures, tachycardia -Rx: Magnesium replacement- oral or iv; avoid magnesium-based antacids/laxatives -Nursing intevertions: assess for chvosteks and trousseau signs, seizure precautions |
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Hypovolemia |
-can occur with loss of normal body fluids (diarrhea, fistual drainage, hemorrhage), decreased intake, or plasma-tointerstitial fluid shift -S/S: Tachycardia, delayed capillary fill, decreased bp, thirst, orthostatic hypotension -tx: balanced iv fluids, isotonic chloride, or blood |
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Hypervolemia |
- may result from excessive intake of fluids, abnormal retention of fluids (chf) or interstitial to plasma fluid shift - s/s: Rapid bounding pulse, edema, wheezes and crackles, distended nack veins -tx: diuretics, fluid restriction, and sodium restriction |
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Urine pH and Specific Gravity Values |
Range for pH- 4.6-8.2 SG: 1.005-1.010 |
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Isotonic Fluids |
- d5w (dextrose in water) - in a bag -.9% NaCl (normal saline) -Lactated ringers (lr) |
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Hypotonic fluids |
- .45% ns (1/2 strength of NS)
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Hypertonic Fluids |
-D5.45%NSS -D10%W -D2.25%NS -D5.9%NSS |
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Infiltration |
- Escape of fluid into subcutaneous tissue -dislodged cannula -penetrated vessel wall -Swelling, edema, pallor, coldness or pain around infusion -D/C, Restart IV |
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Phlebitis |
- inflammation of a vein related to a chemical, mechanical or bacterical irritation - Mechanical: from needle or cath -Chemical: related to infusate -Bacterial: poor aseptic tech/contamination -Red, warm, pain, swelling |
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Normal saline |
- 0.9% NaCl in water - Isotonic -Increases circulating plasma volume when red cells are adequate -Replaces losses without altering fluid concentrations Helpful Na+ replacement |
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1/2 Normal Saline |
- .45% NaCl in water -Hypotonic - Raises total fluid volume - Useful for daily maintenance of body fluid, helpful for establishing renal function, fluid replacement for clients who dont need extra glucose (diabetics) |
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Lactacted ringers (LR) |
-Normal Saline with electrolytes and buffer - isotonic - replasces fluid and buffers pH - normal saline with k+, ca++, and lactate (buffer) -Often seen with surgery |
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D5W |
- DEXTROSE 5% in 0.9% saline -isotonic (in bag) Physiologically hypotonic -Raises total fluid volume, helpful in hydrating and excretory purposes -Provides 170-200 calories/1000cc for energy |
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S1 Heart Sound |
- At the beginning of systole (end of diastole). - Related to the closure of the mitral and tricuspid valves.
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S2 Heart Sound |
- At the beginning of Diastole (end of systole). - Related to the closure of the aortic and pulmonic valves. |
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S3 Heart Sound |
- Ken-tuc-ky- extra sound can be normal in children, late pregnancy or High CO; rarley heard in older adults- associated with CHF |
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S4 Heart Sound |
- ten-nes-see- extra sound can be normal in athletes and elderly- usually abnormal assocaited with CAD, HTN,MI, Aortic or pulmonic stenosis |
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Preload |
degree of stretch on the ventricles |
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Afterload |
it is the aortic pressure the l ventricle muscle must overcome to eject blood |
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Sites for Cardiac Ausculations |
1. Aortic- second r intercostal space 2. Pulmonic- second l intercostal space 3. Erb's Point- 3rd l intercostal space 4. Tricuspid- 4th l intercostal space 5. Mitral- 5th l intercostal space |
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MONA |
-moprhine -oxygen -nitroglycerin -aspirin |
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Systole |
the phase of the heartbeat when the heart contracts and pumps blood from the chambers into the arteries |
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Diastole |
The pahse of the hearbest when the muscle relaxes and allows chambers to fill with blood |
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Palpitation |
A noticable rapid, strong, or irregular heartbeat |
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Murmur |
abnormal sound during heartbeat cycle, such as whooshing or swishing- made by turbulent blood in or near your heart |
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Atreriosclerosis |
the thickening and hardening of the walls of the arteries |
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Atherosclerosis |
deposition of plaques of fatty material on their inner walls |
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Bruit |
the unusual sound that blood makes when it rushes past obstruction (called turbulent flow) in an artery when the sound is ausculated with the bell portion of the stethoscope |
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Function of the lymphatic system |
-Maintain fluid and protein balance - Fight infections
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PItting Edema Scale |
+1 slight pitting, 2 mm depression +2 increasing pitting, 4mm depression +3 deeper pitting, 6 mm depresion, obvious +4 severe pitting, 8mm depression |
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Peripheral pulse sites |
1. Temporal 2. carotid 3. brachial 4. radial 5. femoral 6. Popliteal 7. posterior tibial 8.pedal |
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Grading of Pulses |
0 absent +1 weak, thready +2 weak +3 normal +4 bounding |
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Blood tests to evaluate risks for PAD |
-Arterial Disease: Lipid levels HgB A1C for diabetic patients C reactive protein and homeosysteine levels -Venous: D-Dimer |
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6 p's of arterial occlusion |
Pain Pallor Pulselessness Poikilothermic (coldness) Paralysis Paresthesia |