Step 1- Microbiology: Viruses

Front 1

Live attenuated vaccines?

Back 1

Small Yellow Chickens with Sabin's and MMR get humoral and cell mediated immunity = small pox, yellow fever, chickenpx, Sabin's polio, and MMR

Front 2

Killed vaccines?

Back 2

RIP-A = rabies, Influ, Salk Polio, and HAV

Front 3

What vaccines shouldn't be given to people with egg allergies?

Back 3

Influenza, yellow fever (flavivirus), and caution with MMR

Front 4

Gingivostomatitis to oral lesions. Possibly keratoconjunctivitis or temporal lobe encephalitis

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HSV-1 = DS linear DNA virus with envelope from nuclear membrane (hangs out in the trigeminal ganglia)

Front 5

DDx for neonatal viral encephalitis?

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HSV
CMV

Front 6

Painful genital lesions that recur

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HSV2 = DS linear DNA virus with envelope from nuclear membrane (hangs out in the S2/3 ganglia)

Front 7

Shingles, encephalitis, pneumonia

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VZV = DS linear DNA virus with envelope from nuclear membrane (hang out in the dorsal root ganglia)

Front 8

Negative heterophile mononucleosis and esophagitis with owl's eye inclusions in infected cells

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CMV = Herpesvirus- DS linear DNA virus with envelope from nuclear membrane

Front 9

Fever HSM, pharyngitis, fatigue, and LAD with downy, atypical lymphocytes

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EBV = Herpesvirus- DS linear DNA virus with envelope from nuclear membrane

Front 10

Burkitts, nasopharyngeal ca, and oral hairy leukoplakia

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EBV = Herpesvirus- DS linear DNA virus with envelope from nuclear membrane

Front 11

High fevers in kids that still play followed by diffuse macular rash

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Roseola, HHV-6 = Herpesvirus- DS linear DNA virus with envelope from nuclear membrane

Front 12

Low grade vascular tumor with leukocyte infultrates associated with HIV+ and homosexuals

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Kaposi's sarcoma, HHV-8 = Herpesvirus- DS linear DNA virus with envelope from nuclear membrane

Front 13

Tzanck test revealing multinucleated giant cells with Cowdry A intranuclear inclusions

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HSV or VZV

Front 14

Acute/chronic hepatitis from a virus with reverse transcriptase

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HBV = DS partialy circular DNA virus

Front 15

Sore throat, pneumonia, conjunctivitis (pink eye) and diarrhea

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Adenovirus = DS linear naked DNA virus

Front 16

Kid with acute hemorrhagic cystitis

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#1 cause = Adenovirus = DS linear naked DNA virus

Front 17

Slapped cheeks rash and hydrops fetalis

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Parvovirus B19 = SS linear naked DNA virus (smallest, only SS DNA)

Front 18

Aplastic crises in sickle cell patient

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Parvovirus B19 = SS linear naked DNA virus (smallest, only SS DNA)

Front 19

Warts or cervical intraepithelial neoplasia

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HPV (papillomavirus) = DS circular naked DNA virus

Front 20

Progressive multifocal leukoencephalopathy in HIV pts

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JC virus (polyomavirus) = DS circular naked DNA virus

Front 21

Milksmaid blisters or benign umbillicated warts that regress spontaneously

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Poxvirus = DS DNA virus that doesn't replicate in the nucleus (largest = has it's own DNA-dep RNA polymerase)

Front 22

Foul smelling green diarrhea due to villous distruction (#1 cause of diarrhea in small children)

Back 22

Rotavirus (reovirus) = only DS RNA virus. Naked and segmented. (big in winter and day cares)

Front 23

Colorado tick fever

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Coltivirus (reovirus) = only DS RNA virus. Naked and segmented

Front 24

Flaccid paralysis due to LMN lesion due to destruction of the anterior horns

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Poliovirus (picornavirus) = SS+ linear naked RNA virus

Front 25

Summer cause of myocarditis and aspeptic meningitis

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Echovirus (picornavirus) = SS+ linear naked RNA virus

Front 26

Common cold

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Rhinovirus (picornavirus) = SS+ linear naked RNA virus
Coronavirus (SS + linear RNA - also causes SARS in Asians)

Front 27

Rash on hands and feet with pharyngitis, myocarditis, or meningitis

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CoxsackieA (picornavirus) = SS+ linear naked RNA virus

Front 28

Acute viral hepatitis with no carriers, spread fecal-oral

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HAV (picornavirus) = SS+ linear naked RNA virus

Front 29

Acute viral hepatitis spread by water-borne epidemics and deadly to pregos

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HEV (Hepevirus) = SS+ linear naked RNA virus

Front 30

n/v/d classically associated with cruise ships

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Norwalk virus (calicivirus) = SS+ linear naked RNA virus

Front 31

High fever with black vomiting and jaundice transmitted by mosquitos

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Yellow fever (flavivirus) = SS+ linear RNA virus

Front 32

Summer flu-like sx spread by mosquitos with 1/150 getting severe meningitis/encephalitis

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West Nile virus (flavivirus) = SS+ linear RNA virus

Bird reservoir

Front 33

Fever, post auricular/suboccipital LSD, arthralgias and rash spreading from head to toe

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German measles = rubella (togavirus) = SS+ linear RNA virus

Front 34

PDA, deafness, and cataracts from maternal infection while in utero

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German measles = rubella (togavirus) = SS+ linear RNA virus

Front 35

T-cell leukemia

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HTLV (retrovirus) = SS+ linear RNA virus

Front 36

Flu

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Orthomyxovirus = SS- linear segmented RNA virus

Front 37

Barking seal cough with inspiratory stridor in kid <3 yrs with narrowed trachea on xray

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Croup = parainfluenza (paramyoxovirus) = SS- linear syncytia forming RNA virus
Tx = dexamethasone or epi

Front 38

Bronchiolitis with brassy cough, wheezing and respiratory distress in a kid <2yrs

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RSV (paramyoxovirus) = SS- linear syncytia forming RNA virus

Tx with albuterol/epi NOT steroids or ribavirin

Front 39

Cough, runny nose, conjuctivitis.
Red spots with whit enter on buccal mucosa + rash that spreads head to toe

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Measles = Rubeola (paramyoxovirus) = SS- linear syncytia forming RNA virus

Front 40

Complications = subacute sclerosing panencephalopathy or giant cell pneumonia

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Measles = Rubeola (paramyoxovirus) = SS- linear syncytia forming RNA virus

Front 41

Parotitis, orchitis, and aspetic meningitis

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Mumps (paramyoxovirus) = SS- linear syncytia forming RNA virus

Front 42

Fever to photophobia and hydrophobia to coma to death (likes the hippocampal neurons the best!)

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Rabies (bullet shaped with negri bodies and long incubation period) = Rhabdovirus = SS- linear RNA virus

Front 43

African hemorrhagic fever with DIC

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Ebola/Marburg (filovirus) = SS- linear RNA virus

Front 44

Lymphocytic choriomeningitis or encephalitis spread by mice

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LCMV/Lassa fever (respectfully = arenavirus) = SS- circular segmented RNA virus

Front 45

Chronic blood-borne hepatitis with no vaccine due to antigenic variability in the membrane

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HCV (flavivirus) = SS+ liner RNA virus

Front 46

Hemorrhagic fever and pneumonia from mice

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Hantavirus (bunyavirus) = SS- circular segmented RNA virus

Front 47

California encephalitis, Rift Valley fever, and Crimean hemorrhagic fever

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Bunyaviruses = SS- circular segmented RNA virus (Bunny hate crimes in rift valley california)

Front 48

Defective virus that want's to cause hepatitis but require's B's envelope to do so

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HDV (deltavirus) = SS- circular RNA virus (superinfection worse than coinfection)

Front 49

Which RNA viruses have circular capsids? (generally)

Back 49

(-) strand RNA
Coronavirus