Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
78 Cards in this Set
- Front
- Back
in liver or kidney disease how is the maintenance dose and the loading dose affected
|
maintenance dose will DECREASE
loading dose UNCHANGED |
|
what phase of metabolism do old peeps lose first?
|
Phase I
|
|
what drug is used to dx myasthenia gravis?
|
edrophonium
|
|
what drug is used for an atropine overdose and to treat glaucoma?
|
physostigmine
|
|
how do you treat an organophosphate poisoning?
|
atropine and pralidoxime
|
|
antidote for opioid OD?
|
naloxone/naltrexone
|
|
antidote for heparin OD?
|
protamine
|
|
antidote for benzo OD?
|
flumazenil
|
|
antidote for acetaminophen OD?
|
N-acetylcysteine
|
|
what drugs precipitate gout?
|
furosemide, thiazides
|
|
what are the two partial beta agonists that are NOT for angina?
|
pinolol, acebutolol
|
|
what drug that is used to lower lipids can worsen gout?
|
niacin
|
|
what drug used to decrease lipids can cause gall stones?
|
fibrates
|
|
antidote for Beta blocker OD?
|
glucagon
|
|
dont forget what theophylline does
|
PDE inhibitor used for long term asthma control
|
|
what drug given within 8 hours of acute spinal cord injury can prevent serious long term problems
|
methylprednisolone
|
|
a baby with abnormalities of the skull and face and hypoplasia of finger and toe nails is what disease due to what drug?
|
fetal hydantoin
due to phenytoin |
|
what do the -glitazone drugs do in diabetes?
|
increase the sensitivity of tissues to insulin by increasing the transcription of insulin responsive genes
|
|
benzene damages what?
|
bone marrow leading to pancytopenia
|
|
this drug acts as an GnRH antagonist when given in a continuous fashion and can be used to decrease the size of fibroids in chicks
|
leuprolide
|
|
this drug used for RA can cause retinal deposits
|
hydroxychloroquine
|
|
metronidazole can cause what side effect when mixed with alcohol
|
disulfuram-like reaction
|
|
what is the most feared side effect of macrolides?
|
QT prolongation
|
|
patient has strep and cant take penicillin...whats the next best drug?
|
macrolides
|
|
patients on MAOi's must avoid cheese and wines due to their containing what?
|
tyramine
|
|
what is the first line treatment for diabetes?
|
metformin
|
|
patient presents with sx's of confusion and visual problems...what have they likely OD'ed on and what is the antidote
|
antimuscarinic (like atropine or ipratropium)
give them a drug like physostigmine |
|
antidote for ethylene glycol poisoning?
|
fomepizole
|
|
whats the treatment for pseudomembranous colitis?
|
oral vancomycin
|
|
what is the MOA of tamsulosin
|
alpha 1 antagonist
|
|
what is the primary goal when using niacin?
|
to lower triglycerides
|
|
action of tropicamide?
|
muscarinic antagonist
|
|
how do muscarinic receptors on smooth muscle cause relaxation?
|
via causing the release of NO
|
|
methotrexate can cause macrocytic anemia
|
did ya know that? well now you do
|
|
drug of choice for C. dificil?
|
oral vancomycin
|
|
cyanide poisoning does what in the body?
|
inhibits cytrochrome oxidase
|
|
aspirin OD does what in the body?
|
uncouples ox phos
|
|
chalky white deposits under the skin are seen with what ailment?
|
gout
|
|
what drugs cause osteonecrosis of the jaw?
|
bisphosphonates (-dronates)
|
|
what drugs is a no-no for gout
|
salicylates
|
|
pinpoint pupils in a druggy equal OD with what? whats the antidote
|
opioids
noloxone, naltrexone |
|
what drug is first line for trigeminal neuralgia
|
carbamazepine
|
|
what is the MOA of lamotrigine
|
blocks voltage gated Na channels
|
|
drug that is 1st line for preggo chicks and kids that have seizures?
|
phenobarbitol
|
|
moa of valproic acid
|
inactivate Na channels, increase GABA concentration
|
|
first line for partial seizures?
|
ethosuximide
|
|
phenytoin does what to ladies upper lip?
|
hair growth (hirsutism)
|
|
why is valproic acid not for preggo chicks?
|
it can cause neural tube defects in da baby
|
|
what type of drug is thiopental
|
barbiturate
|
|
whats the most common drug for endoscopy
|
midazolam
|
|
donepezil and galantamine are what kind of drugs?
|
ACh-esterase inhibitors
|
|
halperidol plus -azines are what kind of drugs? what is the MOA
|
antipsychotics
they all block D2 receptors |
|
which antipsychotics cause corneal deposits and which cause retinal deposits
|
Chlorpromazine---Corneal deposits
Thioridazine---reTinal deposits |
|
confusion and hallucination in the elderly is a tox of what drugs?
|
TCA's
|
|
convulsions, coma, cardiotox (arrhythmias)
the 3 C's for tox with what drugs? |
TCAs
|
|
bulimia and social phobias are treated with what?
|
SSRIs
|
|
name the TCAs
|
clomipramine, amitriptyline, nortriptyline, amoxapine, doxepin, imipramine, desipramine
|
|
name the SSRIs
|
fluoxetine, paroxetine, sertraline, citalopram
|
|
bed wetting drug?
|
IMipramine
I'M a bed wetter first try desmopressin though |
|
dude eats a bunch of cheese and wine (fatty) then his BP skyrockets!!! what drug was he one (name 4 potential drugs)
|
selegiline, isocarboxazid, phenelzine, tranylcypromine
|
|
what is tamsulosin?
|
an alpha 1 antagonist used to treat BPH by inhibiting smooth muscle contraction
|
|
class and moa of alprazolam
|
benzodiazepine
agonist at the GABA receptor |
|
which binds the FK-binding protein and which binds mTOR
sirolimus and tacrolimus |
sirolimus---mTOR
tacrolimus---FK-binding protein |
|
what is the first sign of magnesium tox?
|
loss of DTRs
|
|
what anti seizure med is known for causing SLE
|
phenytoin
|
|
the nukes (didanosine, zidovudine) can incorporate themselves into DNA...the non-nukes (efavirenz, nevirapine, declaviridine) do not
|
remember that shiz
|
|
what is the antidote for serotonin syndrome
|
cyproheptadine
|
|
dude ODs on TCAs now his EKG is showing all sorts of whacky stuff...whats the treatment?
|
sodium bicarb (because of the cardio involvement)
|
|
non-anion gap hyperchloric metabolic acidosis is a consequence of what diuretic?
|
acetazolamide
|
|
what is first line for absence seizure treatment?
|
ethosuxamide or valproic acid
|
|
epilepsy drugs and their toxicities are HIGH YIELD for the test
|
LEARN THEM!!! DO IT!!! DO IT NOW!!
|
|
moa of baclofen (for cerebral palsy spasms)
|
binds GABA-b receptors and reduces the release of excitatory neurotransmitters.
|
|
whats first line for strep?
|
penicillin
|
|
what drug should be tried before imipramine for bed wetters?
|
desmopressin
|
|
this drug is good for treating intermittent claudication...its a PDE as well
|
cilostazol
|
|
patient is taking a drug for H. Pylori and now when he goes out in the sun he gets all red and itchy...whats the drug?
|
a tetracycline
|
|
whats the most common side effects of the SSRIs
|
weight gain, loss of libido, insomnia, nausea
|
|
H1 blockers used for allergies and what not have what side effects due to what
|
dry mouth, sedation
due to strong anti muscarinic activity |